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North Estonia Medical Centre Foundation

Verified siteinfo

Estonia J. Sutiste Tee 19, Mustamae Linnaosa, 13419 Tallin, Estonia

  • 28 trials recruiting
  • Psoriatic arthropathy · Non-small cell lung cancer · Acute myeloid leukaemia
  • Adults and children

About Specializations

North Estonia Medical Centre Foundation in Tallin, Estonia specialises in clinical trials of conditions such as Psoriatic arthropathy, Non-small cell lung cancer, Acute myeloid leukaemia, Arteriosclerosis, and other specialisations. This site conducts important research.

Main research areas of the site

Kidney Disease Research

The North Estonia Medical Centre Foundation’s nephrology unit is testing innovative treatments to reduce proteinuria and protect renal function in patients with immunoglobulin A nephropathy and other glomerular disorders.

  • Immunoglobulin A nephropathy
  • Focal segmental glomerulosclerosis
  • Chronic kidney disease
  • End‑stage kidney disease on dialysis
  • Proteinuria reduction strategies

These studies aim to improve long‑term outcomes for individuals with chronic kidney disease and those receiving dialysis.

Cancer and Hematology Trials

Researchers are evaluating new immunotherapies and targeted agents to extend survival in a range of malignancies, including non‑small cell lung cancer and hematologic cancers.

  • Non‑small cell lung cancer
  • Gastric and gastroesophageal adenocarcinoma
  • Metastatic castration‑resistant prostate cancer
  • Acute myeloid leukemia
  • Multiple myeloma
  • Colorectal cancer

The goal is to assess the efficacy of novel drug combinations and improve disease‑free survival across solid tumors and blood cancers.

Cardiovascular and Metabolic Studies

The centre is conducting trials that explore innovative anticoagulants and lipid‑lowering therapies to lower the risk of major cardiovascular events in high‑risk populations, such as those with atrial fibrillation or elevated genetic risk.

  • Atherosclerotic cardiovascular disease
  • Atrial fibrillation
  • Hypercholesterolemia
  • High polygenic risk for coronary artery disease
  • LDL‑cholesterol reduction

These investigations seek to demonstrate reductions in heart attacks, strokes, and cardiovascular mortality.

Autoimmune and Inflammatory Disorders

Ongoing studies focus on biologic and small‑molecule agents designed to control inflammation in conditions such as psoriatic arthritis and inflammatory bowel disease.

  • Psoriatic arthritis
  • Rheumatoid arthritis
  • Moderate to severe ulcerative colitis
  • Crohn's disease
  • Plaque psoriasis

The purpose of these trials is to achieve better symptom control, reduce disease flares, and improve patients’ quality of life.

Infectious and Respiratory Disease Research

The site is evaluating new antimicrobial and antifibrotic compounds to treat serious infections and progressive lung diseases, including complicated urinary tract infections and fibrotic interstitial lung disorders.

  • Complicated urinary tract infection
  • Chronic obstructive pulmonary disease
  • Idiopathic pulmonary fibrosis
  • Progressive fibrosing interstitial lung disease
  • Pulmonary emphysema due to Alpha‑1 antitrypsin deficiency

These trials aim to improve infection cure rates and slow lung function decline in affected patients.

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Site location
J. Sutiste Tee 19, Mustamae Linnaosa13419 TallinEstonia
Recruiting now
28 trials
Conditions studied
67
Partner status
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86 clinical trials

Long-Term Safety and Efficacy of Zasocitinib in Adults with Active Psoriatic Arthritis

Investigational
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:Zasocitinib
  • Sponsor:Takeda Development Center Americas Inc.

Study of sotorasib, panitumumab and a drug combination for patients with metastatic colorectal cancer with KRAS p.G12C mutation.

Registered drugNo placebo
Countries:EstoniaEstonia
  • Participants:18–64 years
  • Substances:Bevacizumab
  • Sponsor:Amgen Inc.

Study of Zasocitinib and Apremilast for Adults with Active Psoriatic Arthritis Who Have Not Used Biologic Medicines

Registered drug
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:Apremilast
  • Sponsor:Takeda Development Center Americas Inc.

Study on Selatogrel for Preventing Heart Attack in Patients with Recent Heart Attack History

Investigational
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:Selatogrel
  • Sponsor:Viatris Innovation GmbH

Study on Clazakizumab for Heart Disease in Adults with End-Stage Kidney Disease on Dialysis

Investigational
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:Clazakizumab
  • Sponsor:CSL Behring LLC

Study on the Effectiveness of Abelacimab for High-Risk Atrial Fibrillation Patients Unsuitable for Oral Anticoagulation

Investigational
Countries:EstoniaEstonia
  • Participants:65+ years
  • Substances:Abelacimab
  • Sponsor:Anthos Therapeutics Inc.

A double‑blind, placebo‑controlled trial of oral BI 1015550 in patients with systemic sclerosis

Investigational
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:BI 1015550
  • Sponsor:Boehringer Ingelheim Espana S.A.

Phase II Study of Teclistamab Plus Pomalidomide in Patients with Relapsed/Refractory Multiple Myeloma After 1–3 Prior Therapies

Registered drugNo placebo
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:Pomalidomide
  • Sponsor:Odense University Hospital

A Study of BI 764532, Atezolizumab, Carboplatin, and Etoposide in Patients With Extensive-Stage Small Cell Lung Cancer

Registered drugNo placebo
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:Atezolizumab
  • Sponsor:Boehringer Ingelheim Espana S.A.

Study of blinatumomab and a drug combination for older adults with newly diagnosed Philadelphia-negative B-cell precursor Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:Asparaginase
  • Sponsor:Amgen Inc.

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Sponsor:Eli Lilly & Co.

Study of glepaglutide compared to placebo for patients with short bowel syndrome with intestinal failure

Investigational
Countries:EstoniaEstonia
  • Participants:18–64 years · 65+ years
  • Substances:Glepaglutide
  • Sponsor:Zealand Pharma A/S
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