A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis
- Substances:–
Poland- Participants:18–64 years
- Sponsor:Zenas Biopharma (USA) LLC
Rare diseases
Investigational molecules
Locations
Ul. Polnocna 8/3, 20-064 Lublin, Poland
Niepubliczny Zaklad Opieki Zdrowotnej Neuromed M. I M. Nastaj. sp.p. in Lublin, Poland specialises in clinical trials of conditions such as Dementia Alzheimer's type, Partial seizures, Non-small cell lung cancer, Parkinson's disease, and other specialisations. This site conducts important research.
The Neuromed site is conducting studies on inflammatory bowel conditions, notably moderate to severe ulcerative colitis, aiming to assess long‑term safety and therapeutic benefit of novel oral agents.
With a total of 36 trials and 11 investigators, the Lublin‑based centre contributes to advancing gastrointestinal therapy in Poland.
Research at Neuromed includes autoimmune disorders such as generalized myasthenia gravis and primary immune thrombocytopenia, focusing on new antibody‑targeted treatments and safety profiling.
The hospital’s multidisciplinary team evaluates innovative immunotherapies to enhance patient outcomes.
The centre is active in oncology trials, particularly for non‑small cell lung cancer with EGFR mutations and HER2‑positive breast cancer, testing targeted agents and combination regimens.
Leveraging its hospital setting, Neuromed supports cutting‑edge cancer research for patients across the region.
Studies at Neuromed address movement and seizure disorders, including Parkinson's disease with motor fluctuations and focal epilepsy, evaluating new oral and injectable therapies.
The site’s neurologists collaborate with 11 investigators to advance neuro‑therapeutic options.
In the respiratory domain, Neuromed focuses on advanced lung cancers, studying advanced/metastatic non‑small cell lung cancer and exploring sequential chemotherapy‑immunotherapy approaches.
These trials complement the centre’s broader oncology program and serve the Lublin patient community.
The facility investigates dermatologic reactions linked to cancer therapy, such as skin toxicities associated with epidermal growth factor receptor inhibitors, aiming to improve management and patient comfort.
By integrating dermatology expertise, Neuromed enhances supportive care for oncology patients.
Clinical research at Neuromed includes neuropsychiatric conditions, notably agitation associated with Alzheimer's disease and psychosis in dementia, testing novel oral compounds for symptom control.
These trials reflect the centre’s commitment to improving mental health care for older adults in Poland.
Clinical trials currently enrolling participants at this site.
PolandOrelabrutinib in Patients with Primary Progressive Multiple Sclerosis
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