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Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie-Panstwowy Instytut Badawczy

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Poland Ul. Garncarska 11, 31-115 Cracow, Poland

  • 8 trials recruiting
  • Malignant melanoma · Triple negative breast cancer · Hormone receptor positive breast cancer
  • Adults and children

About Specializations

Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie-Panstwowy Instytut Badawczy in Cracow, Poland specialises in clinical trials of conditions such as Malignant melanoma, Triple negative breast cancer, Hormone receptor positive breast cancer, Renal cell carcinoma, and other specialisations. This site conducts important research.

Main research areas of the site

Triple Negative Breast Cancer (TNBC)

The Department of Clinical Oncology at the Narodowy Instytut Onkologii is conducting studies that assess new immunotherapy approaches for triple‑negative breast cancer. Trials focus on measuring complete tumor disappearance after surgery and tracking survival without disease recurrence.

  • Pathologic complete response evaluation
  • Event‑free survival analysis
  • Neoadjuvant and adjuvant immunotherapy
  • Combination of checkpoint inhibitor with chemotherapy

Patients benefit from cutting‑edge treatment options while researchers gather data to improve long‑term outcomes.

Renal Cell Carcinoma

Investigators are testing the effectiveness of a checkpoint inhibitor as a single‑agent adjuvant therapy after surgical removal of the kidney. The study aims to determine whether this approach can extend overall survival for patients with renal cell carcinoma.

  • Adjuvant therapy after nephrectomy
  • Overall survival measurement
  • Safety and tolerability assessment
  • Long‑term disease‑free monitoring

The research supports the institute’s commitment to advancing care for patients with advanced kidney cancers.

Advanced Tumor Research

Across multiple solid tumor types, the clinic evaluates novel immunotherapeutic agents to improve response rates and survival. Studies include patients with advanced tumors and assess disease‑free and overall outcomes.

  • Evaluation of disease‑free survival
  • Overall survival endpoints
  • Biomarker-driven patient selection
  • Safety profiling of emerging treatments

The site’s multidisciplinary team collaborates to bring innovative therapies from bench to bedside.

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Site location
Ul. Garncarska 1131-115 CracowPoland
Recruiting now
8 trials
Conditions studied
22
Partner status
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More sites in CracowPoland

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
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21 clinical trials

Study of GSK5764227 alone and in combination for patients with previously treated advanced gastrointestinal tumors that cannot be removed by surgery or have spread

InvestigationalNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:GSK5764227
  • Sponsor:Glaxosmithkline Research & Development Limited

Study on the Long-term Safety and Efficacy of Pembrolizumab and Lenvatinib for Patients with Advanced Tumors

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Favezelimab
  • Sponsor:Merck Sharp & Dohme LLC

Study of nivolumab plus drug combination versus standard first-line therapy in patients with advanced Hodgkin lymphoma

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Brentuximab Vedotin

Long-term Safety Study of Vusolimogene Oderparepvec, RP2, and RP3 in Patients with Melanoma, Liver Cancer, or Advanced Solid Tumors

InvestigationalNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:RP2
  • Sponsor:Replimune Group Inc.

Endometrial cancer+1

Recruiting

A study comparing BNT323 with chemotherapy in patients with HER2-expressing recurrent endometrial cancer who received previous treatment

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:DB-1303
  • Sponsor:BioNTech SE

Study of sacituzumab tirumotecan, pembrolizumab and chemotherapy combination for early-stage triple-negative breast cancer or hormone receptor-low positive/HER2-negative breast cancer

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Merck Sharp & Dohme LLC

Vusolimogene Oderparepvec with Nivolumab for Advanced Melanoma Patients Whose Cancer Progressed After Previous Immunotherapy Treatments

Registered drugNo placebo
Countries:PolandPoland
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Dacarbazine Citrate
  • Sponsor:Replimune Group Inc.

Study of Sacituzumab Tirumotecan and Pembrolizumab for Patients with Triple-Negative Breast Cancer Post-Surgery

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Merck Sharp & Dohme LLC

Malignant peritoneal neoplasm+2

Not yet recruiting

Study on Bevacizumab Dose Equivalence for Patients with Ovarian, Fallopian Tube, or Peritoneal Cancer Using Bevacizumab, Olaparib, Carboplatin, and Paclitaxel

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Agencja Badań Medycznych

Study of Pembrolizumab and Axitinib Combination Versus Sunitinib for Patients with Advanced or Metastatic Kidney Cancer

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Axitinib
  • Sponsor:Merck Sharp & Dohme LLC

Breast cancer+2

Not recruiting

Gedatolisib plus drug combination for HR‑positive, HER2‑negative advanced breast cancer patients whose disease progressed after CDK4/6 inhibitor therapy

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Alpelisib
  • Sponsor:Celcuity Inc.

Malignant melanoma

Not recruiting

Study on Ceralasertib and Durvalumab for Patients with Advanced Melanoma Resistant to PD-(L)1 Therapy

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Ceralasertib
  • Sponsor:AstraZeneca AB
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