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Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy

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Poland Alpejska 42, 04-628 Warsaw, Poland

  • 23 trials recruiting
  • Arteriosclerosis · Atrial fibrillation · Hypertension
  • Adult patients

About Specializations

Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy in Warsaw, Poland specialises in clinical trials of conditions such as Arteriosclerosis, Atrial fibrillation, Hypertension, Cardiac failure, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases

At the Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego, the epidemiology department advances research on cardiovascular diseases by evaluating new therapeutic approaches and assessing their impact on clinical outcomes.

  • Heart failure with preserved or reduced ejection fraction
  • Hypertrophic cardiomyopathy and atrial fibrillation
  • Coronary artery disease and atherosclerotic risk
  • Hypertension, including resistant forms
  • Arrhythmogenic and dilated cardiomyopathies
  • Acute myocardial infarction and post‑event risk reduction

The initiative leverages extensive patient registries to uncover risk patterns and fosters multicenter collaborations throughout Europe.

Nutritional and Metabolic Diseases

Research at the institute focuses on nutritional and metabolic diseases, seeking to improve prevention strategies and evaluate therapies that address obesity, diabetes, and related metabolic disorders.

  • Obesity and overweight in individuals with cardiovascular risk
  • Prediabetes management in patients with coronary artery disease
  • Type 2 diabetes treatment with emerging agents
  • Hyperlipidemia and lipoprotein(a) lowering interventions
  • Uric acid metabolism and its cardiovascular implications

By integrating metabolic profiling, the program aims to identify early biomarkers and support lifestyle‑focused interventions alongside pharmacologic options.

Respiratory Tract Diseases

The epidemiology unit also investigates respiratory tract diseases, emphasizing the interplay between breathing disorders and heart health while testing novel diagnostic and therapeutic measures.

  • Obstructive sleep apnea in overweight adults
  • Pulmonary hypertension secondary to heart failure with preserved ejection fraction
  • Impact of chronic respiratory conditions on cardiovascular outcomes

Collaborative efforts with pulmonology specialists enable comprehensive assessments and the development of integrated care pathways for affected patients.

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Site location
Alpejska 4204-628 WarsawPoland
Recruiting now
23 trials
Conditions studied
39
Partner status
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Ongoing trials

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55 clinical trials

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Zilebesiran
  • Sponsor:Alnylam Pharmaceuticals Inc.

Study of laroprovstat (AZD0780) to reduce heart attack, stroke and vascular complications in patients with atherosclerotic cardiovascular disease or high risk of developing it

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Sponsor:Astrazeneca AB

Study of maridebart cafraglutide to reduce cardiovascular problems in overweight or obese patients with atherosclerotic cardiovascular disease

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:Astrazeneca AB

Study on Selatogrel for Preventing Heart Attack in Patients with Recent Heart Attack History

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Selatogrel
  • Sponsor:Viatris Innovation GmbH

Study on the Use of SYN2, Adenosine, and Regadenoson for Diagnosing Coronary Artery Disease in Patients with Suspected Heart Conditions

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Adenosine

A Phase 3 Randomized, Double-blind,Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants with Obstructive Sleep Apnea not on Positive Airway Pressure Therapy and Living with Overweight or Obesity (MARITIME-OSA-2)

InvestigationalNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.

Effect of elecoglipron plus dapagliflozin on cardiovascular outcomes in adults with heart failure with preserved or mildly reduced ejection fraction (HFpEF/HFmrEF)

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:Astrazeneca AB

Iron deficiency

Recruiting

Effect of Ferric Carboxymaltose, Ferrous Sulfate, and Sodium Chloride vs Placebo on Physical Performance in Frail Elderly with Iron Deficiency and Cardiovascular Disease

Registered drug
Countries:PolandPoland
  • Participants:65+ years
  • Substances:Sodium Chloride
  • Sponsor:Wroclaw Medical University

Cardiac failure+1

Recruiting

Study of Zenagamtide (NNC0487-0111) versus placebo in patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Sponsor:Novo Nordisk A/S

Study of Maridebart Cafraglutide for Adults with Obstructive Sleep Apnea and Overweight or Obesity Who Use Positive Airway Pressure Therapy

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.

A Study of Danicamtiv for Adults with Symptomatic Genetic and Familial Dilated Cardiomyopathy to Test if it Improves Heart Function and Exercise Ability

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Danicamtiv
  • Sponsor:Kardigan Inc.
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