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Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im Prof. Dr Hab. Med. Eleonory Reicher

Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im Prof. Dr Hab. Med. Eleonory Reicher

Research site

Poland Ul. Spartanska 1, 02-637 Warsaw, Poland

  • 31 trials recruiting
  • Sjogren's syndrome · Systemic lupus erythematosus · Psoriatic arthropathy
  • Adults and children

About the site

Centrum Wsparcia Badań Klinicznych - CWBK (Clinical Trials Support Center) of the National Institute of Geriatrics, Rheumatology and Rehabilitation (NIGRiR) is a site conducting clinical trials in fields such as: rheumatology, immunology, neurology, cardiology, orthopedics, rehabilitation, pulmonology, and dermatology. In our modern center, clinical trials are conducted at the highest standard and with maximum comfort for patients.

CWBK, as a highly specialized unit, conducts clinical trials for patients from all over Poland, with particular attention to those who present diagnostic and therapeutic challenges, for whom participation in clinical trials may be the only chance to improve health, slow disease progression, or achieve remission.

The mission of CWBK’s experienced medical teams – doctors and nurses – is to ensure patients have access to modern forms of treatment, improving their health and quality of life, while maintaining the highest global standards of safety and respect for patient rights. The medical staff at CWBK is supported by a team of qualified administrative professionals experienced in managing medical and laboratory documentation in accordance with Good Clinical Practice (GCP) guidelines.

CWBK is actively involved in scientific and clinical initiatives with national and international research communities, paving the way for new projects, diagnostic methods, and future treatment solutions – namely, personalized medicine. The opportunity for these patients to participate in clinical trials not only opens access to drugs and therapies not financed by the National Health Fund (NFZ) but also reduces the cost of accessing and delivering treatment.

About Specializations

Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im Prof. Dr Hab. Med. Eleonory Reicher in Warsaw, Poland specialises in clinical trials of conditions such as Sjogren's syndrome, Systemic lupus erythematosus, Psoriatic arthropathy, Axial spondyloarthritis, and other specialisations. This site conducts important research.

Main research areas of the site

Interstitial Lung Disease

The medical center is at the forefront of research in interstitial lung disease associated with systemic connective tissue diseases and hypersensitivity. The focus is on evaluating the efficacy of novel therapies like pirfenidone and nintedanib, aiming to improve patient outcomes and quality of life.

  • Systemic Connective Tissue Disease
  • Hypersensitivity Pneumonitis

Through rigorous clinical trials, the center is advancing the understanding of these complex conditions, contributing to the development of more effective treatment protocols.

Systemic Lupus Erythematosus (SLE)

Specializing in Systemic Lupus Erythematosus, the center conducts extensive research to assess the safety and efficacy of innovative treatments like ESK-001 and deucravacitinib. These studies aim to enhance disease management and patient care.

  • British Isles Lupus Assessment Group (BILAG)
  • Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)

The center's work is pivotal in developing new therapeutic strategies that address the diverse manifestations of SLE.

Psoriatic and Axial Spondyloarthritis

Research at the center includes a focus on psoriatic arthritis and axial spondyloarthritis, with studies on treatments like secukinumab and filgotinib. These efforts aim to improve long-term safety and efficacy in managing these chronic conditions.

  • Chronic Plaque Psoriasis
  • Ankylosing Spondylitis

By exploring new treatment avenues, the center is enhancing therapeutic options for patients with these debilitating diseases.

Osteoarthritis

The center is pioneering research in knee osteoarthritis, focusing on the regenerative potential of treatments like RHH646. This research aims to provide innovative solutions for cartilage repair and pain management.

  • Articular Cartilage Regeneration
  • Long-term Safety and Tolerability

These studies are crucial in developing therapies that can significantly improve the quality of life for osteoarthritis patients.

Polymyalgia Rheumatica

Focusing on polymyalgia rheumatica, the center evaluates the efficacy of secukinumab in combination with glucocorticoid taper regimens. This research is vital for advancing treatment strategies for patients experiencing relapses.

  • Glucocorticoid Taper Regimen
  • Sustained Remission

The center's work is instrumental in refining therapeutic approaches to achieve better patient outcomes.

Atrial Fibrillation

In the field of atrial fibrillation, the center is investigating the efficacy of abelacimab in reducing the risk of ischemic stroke. This research is crucial for patients unsuitable for traditional oral anticoagulation therapy.

  • Ischemic Stroke Prevention
  • Anticoagulation Alternatives

Through these studies, the center is contributing to safer and more effective management of atrial fibrillation.

Dermatomyositis and Polymyositis

The center is advancing research in dermatomyositis and polymyositis, focusing on treatments like enpatoran and brepocitinib. These studies aim to improve muscle function and reduce disease activity.

  • American College of Rheumatology (ACR) Criteria
  • European League Against Rheumatism (EULAR) Criteria

By exploring new therapeutic options, the center is enhancing care for patients with these inflammatory myopathies.

IgG4-Related Disease

Research at the center includes a focus on IgG4-related disease, with studies on the effects of obexelimab. This research is essential for understanding and managing disease flares effectively.

  • Glucocorticoid Therapy
  • Long-term Safety and Tolerability

The center's work is pivotal in developing targeted therapies for this complex condition.

Gout and Hyperuricemia

The center is at the forefront of research in gout and hyperuricemia, evaluating the efficacy of tigulixostat compared to allopurinol. This research aims to optimize uric acid management and improve patient outcomes.

  • Uric Acid Reduction
  • Comparative Efficacy Studies

Through these studies, the center is enhancing therapeutic strategies for managing gout effectively.

Sjögren's Syndrome

Specializing in Sjögren's syndrome, the center conducts research on treatments like deucravacitinib and efgartigimod. These studies focus on improving disease activity and long-term safety.

  • ESSDAI Improvement
  • Long-term Safety Studies

The center's work is crucial in developing effective management strategies for this autoimmune condition.

Giant Cell Arteritis

Research at the center includes a focus on giant cell arteritis, comparing the efficacy of etanercept and methotrexate. This research is vital for achieving steroid-free remission in patients.

  • Steroid-free Remission
  • Comparative Treatment Efficacy

Through these studies, the center is enhancing therapeutic options for managing giant cell arteritis.

Androgenetic Alopecia

The center is pioneering research in androgenetic alopecia, focusing on the efficacy and safety of clascoterone solution. This research aims to provide innovative solutions for hair loss management.

  • Hair Regrowth Efficacy
  • Safety and Tolerability

These studies are crucial in developing therapies that can significantly improve the quality of life for patients with hair loss.

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Site location
Ul. Spartanska 102-637 WarsawPoland
Recruiting now
31 trials
Conditions studied
49

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
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Quick filters

86 clinical trials

Obesity+2

Recruiting

Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease

Investigational
Countries:PolandPoland
  • Participants:18–64 years
  • Substances:POLYPEPTIDE CONSISTING OF A GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST AND AN AMYLIN RECEPTOR AGONIST, CONNECTED BY A LINKER WITH 4 GLYCINE RESIDUES, AND CONNECTED TO A C18 FATTY ACID SIDE CHAIN
  • Sponsor:Novo Nordisk A/S

Evaluation of Anifrolumab Subcutaneous Treatment in Immunosuppressant‑Naïve and Biologic‑Naïve Patients with Systemic Lupus Erythematosus

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Anifrolumab
  • Sponsor:AstraZeneca AB

Long-Term Safety and Efficacy of Zasocitinib in Adults with Active Psoriatic Arthritis

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Zasocitinib
  • Sponsor:Takeda Development Center Americas Inc.

Obesity+2

Recruiting

A study to evaluate the effects of zenagamtide on weight and pain in patients with overweight or obesity and knee osteoarthritis

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:POLYPEPTIDE CONSISTING OF A GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST AND AN AMYLIN RECEPTOR AGONIST, CONNECTED BY A LINKER WITH 4 GLYCINE RESIDUES, AND CONNECTED TO A C18 FATTY ACID SIDE CHAIN
  • Sponsor:Novo Nordisk A/S

Obesity+2

Recruiting

A study to evaluate the efficacy and safety of zenagamtide in people with overweight or obesity and knee osteoarthritis

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:POLYPEPTIDE CONSISTING OF A GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST AND AN AMYLIN RECEPTOR AGONIST, CONNECTED BY A LINKER WITH 4 GLYCINE RESIDUES, AND CONNECTED TO A C18 FATTY ACID SIDE CHAIN
  • Sponsor:Novo Nordisk A/S

Psoriasis

Recruiting

Long-term safety study of deucravacitinib compared to ustekinumab in adults with moderate to severe plaque psoriasis

Registered drugNo placebo
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Deucravacitinib
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Study of vicadrostat and empagliflozin combination in patients with type 2 diabetes, high blood pressure and cardiovascular disease

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:BI 690517
  • Sponsor:Boehringer Ingelheim Espana S.A.

Dermatomyositis+1

Recruiting

Study on Anifrolumab for Adults with Polymyositis or Dermatomyositis

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Anifrolumab
  • Sponsor:AstraZeneca AB

Study on the Effectiveness of Abelacimab for High-Risk Atrial Fibrillation Patients Unsuitable for Oral Anticoagulation

Investigational
Countries:PolandPoland
  • Participants:65+ years
  • Substances:Abelacimab
  • Sponsor:Anthos Therapeutics Inc.

Phase III trial evaluating ianalumab with background drug combination in patients with Sjögren's disease

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Emtricitabine
  • Sponsor:Novartis Pharma AG

Tulisokibart for Psoriatic Arthritis in Adults

Investigational
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Tulisokibart
  • Sponsor:Merck Sharp & Dohme LLC

A study to evaluate the safety and effects of inebilizumab in children and adolescents with immunoglobulin G4-related disease

Registered drugNo placebo
Countries:PolandPoland
  • Participants:0–17 years
  • Substances:Inebilizumab
  • Sponsor:Amgen Inc.
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