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Narodni Ustav Dusevniho Zdravi

Research site

Czechia Topolova 748, 250 67 Klecany, Czechia

  • 7 trials recruiting
  • Major depression · Narcolepsy · Schizophrenia
  • Adult patients

About Specializations

Narodni Ustav Dusevniho Zdravi in Klecany, Czechia specialises in clinical trials of conditions such as Major depression, Narcolepsy, Schizophrenia, Anxiety, and other specialisations. This site conducts important research.

Main research areas of the site

Neurodegenerative & Motor Disorders

The clinic at Narodni Ustav Dusevniho Zdravi is conducting studies on conditions such as multiple sclerosis, amyotrophic lateral sclerosis, and atypical Parkinsonian disorders including multiple system atrophy, progressive supranuclear palsy, and corticobasal syndrome. Trials aim to evaluate novel therapeutic approaches and assess safety of emerging treatments.

  • Novel disease-modifying agents
  • Neuroprotective strategies
  • Symptom management
  • Biomarker discovery

Emphasis on integrating advanced diagnostic techniques and patient‑centered outcomes.

Psychiatric & Treatment‑Resistant Disorders

Research at the site focuses on severe mental health illnesses such as major depressive disorder, treatment‑resistant depression, and treatment‑resistant schizophrenia. The objective is to test innovative compounds and psychedelic‑assisted therapies for rapid symptom relief and long‑term safety.

  • Adjunctive antidepressant therapies
  • Psychedelic‑assisted psychotherapy
  • New antipsychotic agents
  • Safety monitoring in chronic use

Collaboration with multidisciplinary teams ensures comprehensive evaluation of both efficacy and tolerability.

Respiratory & Comorbid Disease Research

Clinical investigations include patients with chronic obstructive pulmonary disease who also suffer from depressive symptoms, exploring how mental health interventions can improve overall wellbeing.

  • Depression management in COPD
  • Integrated care models
  • Impact of mental health on respiratory outcomes
  • Patient‑reported outcome measures

The program leverages the clinic’s expertise in both pulmonary care and psychosocial support.

Diagnostic & Therapeutic Techniques

The institution is advancing analytical, diagnostic and therapeutic equipment to support trials across multiple disease areas, enabling precise measurement of treatment effects.

  • Advanced imaging biomarkers
  • Digital health monitoring
  • Standardized rating scales
  • Safety assessment protocols

These tools are applied across neurodegenerative, psychiatric, and respiratory studies to enhance data quality.

Behavioral & Psychological Phenomena

Studies examine the underlying behavioral mechanisms and psychological phenomena associated with chronic illness, aiming to refine supportive interventions.

  • Behavioral therapy integration
  • Coping strategies in chronic disease
  • Quality‑of‑life assessments
  • Psychiatric comorbidity profiling

Findings inform personalized care pathways within the clinic’s multidisciplinary framework.

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Site location
Topolova 748250 67 KlecanyCzechia
Recruiting now
7 trials
Conditions studied
10

More sites in KlecanyCzechia

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

14 clinical trials

Narcolepsy

Recruiting

Phase 3 Randomized, Double‑Blind, Placebo‑Controlled Study of ALKS 2680 for Excessive Daytime Sleepiness in Adults with Narcolepsy Type 2

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:ALKS 2680
  • Sponsor:Alkermes Inc.

Narcolepsy

Recruiting

Phase 3 Randomized Study of ALKS 2680 for Excessive Daytime Sleepiness in Adults with Narcolepsy Type 1

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:ALKS 2680
  • Sponsor:Alkermes Inc.

Schizophrenia

Recruiting

Study of evenamide as add-on treatment for patients with treatment-resistant schizophrenia not adequately controlled by current antipsychotic medications

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Evenamide
  • Sponsor:Newron Pharmaceuticals S.p.A.

Safety and Tolerability Study of NBI-1065845 as Additional Treatment for Adults with Major Depressive Disorder

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:9-(4-CYCLOHEXYLOXYPHENYL)-7-METHYL-3,4-DIHYDROPYRAZINO[2,1-C][1,2,4]THIADIAZINE 2,2-DIOXIDE
  • Sponsor:Neurocrine Biosciences Inc.

Narcolepsy+1

Recruiting

Long-Term Study on the Safety and Effects of ALKS 2680 for Patients with Narcolepsy Type 1 and Type 2

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:ALKS 2680
  • Sponsor:Alkermes Inc.

Depression

Recruiting

Study on Psilocybin, Ketamine, and Midazolam for Treating Depression in Cancer Patients

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Midazolam
  • Sponsor:Narodni Ustav Dusevniho Zdravi

Palliative care+1

Recruiting

Study of psilocybin therapy for psychological distress in patients with COPD, ALS, multiple sclerosis, or atypical Parkinson's disorders

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Psilocybine
  • Sponsor:Universitair Medisch Centrum Groningen

Anxiety

Not yet recruiting

Efficacy of Etifoxine in Adults with Adjustment Disorder with Anxiety: A Randomized, Double‑Blind, Placebo‑Controlled Trial

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Etifoxine Hydrochloride
  • Sponsor:Biocodex

Schizophrenia

Not recruiting

Study on Long-Term Safety of Iclepertin for Patients with Schizophrenia Who Completed Previous Trials

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years
  • Substances:Iclepertin
  • Sponsor:Boehringer Ingelheim International GmbH

Major depression

Not recruiting

Testing Ulotaront Added to Antidepressants for Adults with Major Depressive Disorder Who Did Not Respond Well to Initial Treatment

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Citalopram
  • Sponsor:Otsuka Pharmaceutical Development & Commercialization Inc.

Major depression

Not recruiting

Study on the Safety and Effectiveness of Aticaprant with Antidepressants for Adults and Elderly with Major Depressive Disorder

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Aticaprant
  • Sponsor:Janssen Cilag International

Major depression

Not recruiting

Study on Psilocybin, Ketamine, and Midazolam for Patients with Treatment-Resistant Depression

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years
  • Substances:Midazolam
  • Sponsor:Narodni Ustav Dusevniho Zdravi
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