Multiprofile Hospital For Active Treatment Ivan Skenderov EOOD

The Clinic of Cardiology at Multiprofile Hospital For Active Treatment Ivan Skenderov EOOD focuses on innovative studies aimed at improving outcomes for patients with heart failure and related conditions.

• Evaluation of a novel therapy (JTT-861) for heart failure with reduced ejection fraction
• Combination of vicadrostat and empagliflozin to reduce cardiovascular death and hospitalisation
• Investigation of NNC0487-0111 in HFpEF and obesity

These trials aim to test new treatments, assess safety, and measure impacts on hospitalization and mortality, offering hope for better management of chronic cardiac conditions.

Research at the site includes studies targeting the early treatment of acute myocardial infarction (AMI) to lower the risk of future cardiovascular events.

• Self‑administered selatogrel for rapid symptom relief in suspected AMI
• Monthly ziltivekimab injections to reduce inflammation and major adverse cardiovascular events after AMI
• Exploration of inflammatory pathways (IL‑6) as a therapeutic target in post‑AMI patients

The primary goal is to demonstrate efficacy and safety of these approaches, potentially shaping new standards for post‑heart‑attack care.