A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis
- Substances:–
Poland- Participants:18–64 years
- Sponsor:Zenas Biopharma (USA) LLC
Rare diseases
Investigational molecules
Locations
Ul. Gładka 22, 02-172 Warsaw, Poland
Mtz Clinical Research Powered By Pratia in Warsaw, Poland specialises in clinical trials of conditions such as Migraine, Partial seizures, Myelodysplastic syndrome, Major depression, and other specialisations. This site conducts important research.
The Clinical Unit at Mtz Clinical Research Powered By Pratia is conducting studies focused on disorders of the nervous system, aiming to test innovative treatments that improve neurological function and quality of life.
Across 81 trials, 52 investigators are exploring disease‑modifying approaches for these conditions, offering patients access to cutting‑edge therapeutic options.
Research at the site spans solid tumors and blood cancers, evaluating novel agents that target tumor growth and improve survival outcomes.
The program includes combination regimens and immunotherapy strategies, reflecting a commitment to advancing cancer care in Warsaw.
The facility is engaged in trials that assess cardiovascular risk reduction and metabolic disease management, testing therapies that aim to lower events and improve metabolic parameters.
With a strong focus on heart failure and lipid‑lowering agents, the trials support personalized cardiovascular therapy for diverse patient populations.
Studies at the Warsaw site target conditions driven by immune dysregulation, evaluating biologics and small molecules that modulate immune pathways.
The trials aim to reduce disease activity and improve patient‑reported outcomes, positioning the center as a hub for immune‑targeted research.
The clinical program includes investigations of new agents for chronic inflammatory skin conditions, seeking to achieve faster symptom relief and long‑term disease control.
By testing targeted inhibitors and biologics, the site contributes to expanding therapeutic choices for patients with difficult‑to‑treat skin diseases.
Research efforts encompass viral infections and respiratory conditions, focusing on preventive vaccines and antiviral therapies to reduce disease burden.
These studies aim to enhance immunity and provide effective treatment options for both acute and chronic respiratory infections.
The site’s psychiatric portfolio investigates novel interventions for mood and anxiety disorders, targeting symptom reduction and relapse prevention.
By integrating pharmacologic and behavioral endpoints, the trials support a holistic approach to mental health care.
Clinical trials currently enrolling participants at this site.
PolandLong‑Term Safety and Efficacy of SPY001-001, SPY002 and SPY003 in Adults with Ulcerative Colitis
PolandOrelabrutinib in Patients with Primary Progressive Multiple Sclerosis
PolandLong-Term Safety and Efficacy of Zasocitinib in Adults with Active Psoriatic Arthritis
PolandA Study of Long-acting Antibodies SPY001-001 and SPY002 Alone and Combined for Adults with Moderate to Severe Ulcerative Colitis
PolandStudy of SPN-817 (Huperzine A) in Adults with Focal Onset Seizures: Testing Safety and Effectiveness of Treatment
PolandStudy of vicadrostat and empagliflozin combination in patients with type 2 diabetes, high blood pressure and cardiovascular disease
PolandStudy of Zasocitinib and Apremilast for Adults with Active Psoriatic Arthritis Who Have Not Used Biologic Medicines
PolandStudy on Seltorexant for Adults and Elderly with Major Depressive Disorder and Insomnia Symptoms
PolandStudy on the Effects of Pegozafermin for Patients with Nonalcoholic Steatohepatitis (NASH) and Fibrosis
PolandStudy on BI 690517 and Empagliflozin for Patients with Heart Failure and Preserved Ejection Fraction
PolandStudy of Pegozafermin Treatment for Patients with Liver Cirrhosis due to Metabolic Dysfunction-Associated Steatohepatitis (MASH)
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