A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis
- Substances:–
Czechia- Participants:18–64 years
- Sponsor:Zenas Biopharma (USA) LLC
Rare diseases
Investigational molecules
Locations
Havlickovo Nabrezi 600, 760 01 Zlin, Czechia
Krajska Nemocnice T Bati a.s. in Zlin, Czechia specialises in clinical trials of conditions such as Multiple sclerosis, Arteriosclerosis, Relapsing multiple sclerosis, Squamous cell carcinoma of head and neck, and other specialisations. This site conducts important research.
The clinic conducts studies aimed at improving procedural safety and diagnostic accuracy for acute conditions, evaluating novel fluid‑management strategies during neurosurgery and assessing minimally invasive approaches for stroke and pulmonary embolism.
Krajska Nemocnice T Bati a.s. supports these technique‑focused trials to enhance patient outcomes.
Trials target major heart and vascular events, testing innovative anti‑inflammatory and antithrombotic agents to reduce recurrence of myocardial infarction and prevent ischemic stroke after acute episodes.
Research at the oncology clinic integrates cardiovascular expertise to address these life‑threatening conditions.
Studies evaluate the long‑term efficacy of biologic therapies for inflammatory bowel disorders, aiming to induce remission and improve quality of life for patients with Crohn’s disease and ulcerative colitis.
The site’s multidisciplinary team collaborates to bring cutting‑edge treatments to patients with gastrointestinal inflammation.
Oncologic trials explore targeted and immunotherapies for various solid tumours, seeking better response rates and longer progression‑free survival in conditions such as non‑small cell lung cancer, ER+/HER2‑ advanced breast cancer, and head and neck squamous cell carcinoma.
Krajska Nemocnice T Bati a.s.’s oncology clinic leverages these trials to expand therapeutic options for cancer patients.
Investigations focus on disease‑modifying agents for multiple sclerosis, aiming to slow disability progression and reduce relapse rates in both relapsing‑remitting and secondary progressive forms.
Through these studies, the clinic contributes to advancing neuro‑immunology treatments.
Clinical trials currently enrolling participants at this site.
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