Cardiovascular Diseases

Klinische Forschung Dresden GmbH is advancing the understanding of cardiovascular disease through a series of therapeutic trials.

  • Atherosclerotic cardiovascular disease
  • Atrial fibrillation
  • Heart failure
  • Hypertension
  • Elevated lipoprotein(a)
  • Uncontrolled resistant hypertension

The focus is on evaluating new agents that lower the risk of stroke, myocardial infarction and improve blood‑pressure control.

Digestive System Diseases

Research efforts target functional gastrointestinal disorders, notably irritable bowel syndrome.

  • Diarrhoea‑predominant irritable bowel syndrome
  • Mixed‑type irritable bowel syndrome
  • Chronic functional bowel discomfort

Trials aim to test novel therapies that enhance gut motility and reduce symptom burden.

Hormonal diseases

The site investigates conditions driven by hormonal imbalance, including female androgenetic alopecia.

  • Female androgenetic alopecia
  • Hormone‑imbalanced hair loss in women

Studies assess oral minoxidil combined with topical formulations to promote hair regrowth.

Immune System Diseases

Clinical programs address immune‑mediated disorders such as chronic spontaneous urticaria.

  • Chronic spontaneous urticaria
  • Moderate to severe plaque psoriasis
  • Seasonal allergic rhinitis

The objective is to evaluate biologics and small molecules that achieve rapid symptom control and durable remission.

Musculoskeletal Diseases

Trials focus on joint health and pain management, highlighted by research on knee osteoarthritis.

  • Knee osteoarthritis
  • Chronic non‑specific low back pain
  • Musculoskeletal chronic pain

Efforts aim to identify treatments that reduce pain intensity and improve functional capacity.

Nervous System Diseases

Neurological studies include investigations of diabetic peripheral neuropathic pain.

  • Diabetic peripheral neuropathic pain
  • Chronic neuropathic pain
  • Insomnia disorder

The goal is to provide more effective analgesic options and improve sleep quality for affected patients.

Nutritional and Metabolic Diseases

Research targets metabolic health challenges, with a focus on obesity and dyslipidaemia.

  • Obesity
  • Hyperlipidemia
  • Elevated lipoprotein(a)

Studies evaluate weight‑loss agents and lipid‑lowering therapies to diminish cardiovascular risk.

Respiratory Tract Diseases

The centre conducts respiratory investigations, including an influenza vaccine study.

  • Influenza
  • Chronic obstructive pulmonary disease
  • Refractory chronic cough
  • Respiratory syncytial virus infection

Objectives are to improve vaccine efficacy and to alleviate persistent cough symptoms.

Skin and Connective Tissue Diseases

Dermatologic research centers on inflammatory skin conditions, especially plaque psoriasis.

  • Moderate to severe plaque psoriasis
  • Chronic spontaneous urticaria
  • Therapy‑resistant chronic venous ulcers

Trials test biologics, small molecules and advanced wound‑healing products to achieve clear skin and ulcer closure.

Virus Diseases

Antiviral efforts include evaluation of an mRNA influenza vaccine and other respiratory viruses.

  • Influenza
  • Respiratory syncytial virus (RSV)
  • Human metapneumovirus (hMPV)
  • RSV lower respiratory tract disease

The aim is to enhance immune protection in older adults and reduce virus‑related morbidity.

Behavioral Disciplines and Activities

Behavioral studies explore lifestyle‑related conditions, with emphasis on sleep disorders.

  • Insomnia disorder
  • Alcohol use disorder
  • Seasonal allergic rhinitis (behavioral impact)

Research evaluates both pharmacologic and non‑pharmacologic interventions to improve daily functioning.

Mental Disorders

Mental health trials focus on mood disorders, particularly major depressive disorder.

  • Mild to moderate major depressive disorder
  • Alcohol use disorder
  • Depressive symptoms associated with chronic pain

The objective is to identify effective treatments that alleviate depressive symptoms while maintaining a favorable safety profile.