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Klinikum Wuerzburg Mitte gGmbH

Research site

Germany Salvatorstrasse 7, Frauenland, 97074 Wuerzburg, Germany

  • 10 trials recruiting
  • Non-small cell lung cancer · Myasthenia gravis · Non-small cell lung cancer metastatic
  • Adult patients

About Specializations

Main research areas of the site

Neoplasms (Oncology)

At Klinikum Wuerzburg Mitte gGmbH, investigators are studying metastatic non‑small cell lung cancer with the aim of testing new targeted agents and immunotherapy combinations to improve survival outcomes.

  • Evaluation of ROS1‑positive tumor targeting therapies
  • Combination of checkpoint inhibitors with antibody‑drug conjugates
  • Assessment of progression‑free survival as a primary endpoint
  • Comparison of overall survival benefits across treatment arms

Results are expected to shape future lung‑cancer treatment guidelines and provide new options for patients with advanced disease.

Nervous System Diseases

The research team is also dedicated to advancing care for multiple sclerosis, focusing on the long‑term safety and tolerability of oral therapies for both relapsing and progressive forms of the disease.

  • Long‑term safety monitoring of BTK inhibitor treatment
  • Inclusion of relapsing‑remitting and progressive patient cohorts
  • Evaluation of neurological function preservation
  • Impact on patients’ quality of life and daily activities

Findings will help clinicians choose safer, more effective strategies for managing chronic nervous‑system disorders.

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Site location
Salvatorstrasse 7, Frauenland97074 WuerzburgGermany
Recruiting now
10 trials
Conditions studied
23

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Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
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Quick filters

30 clinical trials

Countries:GermanyGermany
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Sponsor:Sanofi Vaccines US Inc.

Phase III Randomized Study of Rilvegostomig vs. Pembrolizumab with Platinum-based Chemotherapy in PD-L1 Expressing Metastatic Squamous NSCLC

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:AstraZeneca AB

Study comparing rilvegostomig plus chemotherapy versus pembrolizumab plus chemotherapy for first-line treatment in patients with metastatic non-squamous lung cancer with PD-L1 expression

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:AstraZeneca AB

Adjuvant Therapy with RO7435846 (divarasib) versus Pembrolizumab or Nivolumab or Observation in Patients After Surgery for Stage II‑III KRAS G12C NSCLC

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Divarasib
  • Sponsor:F. Hoffmann-La Roche AG

A Study of Depemokimab Compared to Placebo in Adults with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Depemokimab
  • Sponsor:Glaxosmithkline Research & Development Limited

A Study of IMVT-1402 in Adults with Chronic Inflammatory Demyelinating Polyneuropathy to Prevent Disease Relapse

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Imeroprubart
  • Sponsor:Immunovant Sciences GmbH

Study of IMVT-1402 in Adults with Mild to Severe Generalized Myasthenia Gravis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Imeroprubart
  • Sponsor:Immunovant Sciences GmbH

Study of BMS-986368 to treat muscle stiffness in people with Multiple Sclerosis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:CC-97489
  • Sponsor:Celgene Corp.

Study of Amivantamab, Lazertinib, and Pemetrexed for Patients with Advanced or Metastatic Solid Tumors, Including EGFR-Mutated Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Amivantamab
  • Sponsor:Janssen Cilag International

Study on Long-Term Safety of Tolebrutinib and Teriflunomide for Patients with Multiple Sclerosis

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Teriflunomide
  • Sponsor:Sanofi-Aventis Recherche & Developpement

K-ras gene mutation+2

Not yet recruiting

Study of divarasib and pembrolizumab compared to standard chemotherapy in previously untreated KRAS G12C-mutated advanced non-small cell lung cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:F. Hoffmann-La Roche AG

Study on Datopotamab Deruxtecan and Rilvegostomig for Stage I Non-Small Cell Lung Cancer Patients with ctDNA-Positive or High-Risk Features

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:AstraZeneca AB
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