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Kempenhaeghe

Research site

The Netherlands Sterkselseweg 65, 5591 VE Heeze, The Netherlands

  • 8 trials recruiting
  • Partial seizures · Narcolepsy · Generalised tonic-clonic seizure
  • Adults and children

About Specializations

Kempenhaeghe in Heeze, The Netherlands specialises in clinical trials of conditions such as Partial seizures, Narcolepsy, Generalised tonic-clonic seizure, Epilepsy, and other specialisations. This site conducts important research.

Main research areas of the site

Epilepsy Therapeutics Research

The Sleep Medicine Centre at Kempenhaeghe is advancing treatment options for epilepsy. Studies aim to lower seizure counts and evaluate long‑term safety of emerging medicines.

  • Refractory epilepsy
  • Primary generalized tonic‑clonic seizures
  • Focal onset seizures
  • Dravet syndrome and Lennox‑Gastaut syndrome
  • Idiopathic generalized epilepsy
  • Adjunctive cannabidiol therapy
  • Novel oral agents such as XEN1101 and BHV‑7000

A total of nine trials involving five investigators are currently recruiting or ongoing, offering patients access to cutting‑edge interventions while generating data that could reshape seizure management.

Sleep and Neurological Conditions

Research at the centre also addresses sleep disturbances that accompany neurological disease. The goal is to improve sleep quality and overall wellbeing through targeted therapies.

  • Insomnia management in adults
  • Sleep quality in multiple sclerosis
  • Impact of cannabidiol on sleep patterns
  • Non‑pharmacologic sleep interventions
  • Sleep monitoring in patients with epilepsy

By integrating sleep assessments into epilepsy trials, the site provides a holistic view of patient health, supporting better outcomes for both seizure control and restorative rest.

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Site location
Sterkselseweg 655591 VE HeezeThe Netherlands
Recruiting now
8 trials
Conditions studied
9

More sites in HeezeThe Netherlands

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

14 clinical trials

Narcolepsy

Recruiting

Phase 3 Randomized, Double‑Blind, Placebo‑Controlled Study of ALKS 2680 for Excessive Daytime Sleepiness in Adults with Narcolepsy Type 2

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:ALKS 2680
  • Sponsor:Alkermes Inc.

Narcolepsy

Recruiting

Phase 3 Randomized Study of ALKS 2680 for Excessive Daytime Sleepiness in Adults with Narcolepsy Type 1

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:ALKS 2680
  • Sponsor:Alkermes Inc.

Study on the Safety of BHV-7000 for Adults with Hard-to-Treat Focal Onset Epilepsy

InvestigationalNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:BHV-7000
  • Sponsor:Biohaven Therapeutics Ltd.

Narcolepsy+1

Recruiting

Long-Term Study on the Safety and Effects of ALKS 2680 for Patients with Narcolepsy Type 1 and Type 2

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:ALKS 2680
  • Sponsor:Alkermes Inc.

Epilepsy

Recruiting

Study on Cannabidiol and Dronabinol for Children with Refractory Epilepsy

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:0–17 years
  • Substances:Cannabidiol
  • Sponsor:Universitair Medisch Centrum Utrecht

Study on the Long-term Safety and Tolerability of Azetukalner for Patients with Epilepsy, Including Focal-onset and Primary Generalized Tonic-Clonic Seizures

InvestigationalNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Study on the Effects of Azetukalner in Patients with Focal-Onset Seizures

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Study on the Effects of XEN1101 and Placebo for Patients with Primary Generalized Tonic-Clonic Seizures

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Partial seizures

Not yet recruiting

Study on the Effectiveness and Safety of BHV-7000 for Adults with Refractory Focal Onset Epilepsy

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:BHV-7000
  • Sponsor:Biohaven Therapeutics Ltd.

Study on BHV-7000 for Patients with Generalized Tonic-clonic Seizures in Idiopathic Generalized Epilepsy

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:BHV-7000
  • Sponsor:Biohaven Therapeutics Ltd.

Insomnia

Not recruiting

Study on the Effect of Cannabidiol (CBD) on Sleep Quality in Multiple Sclerosis Patients with Insomnia

Investigational
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Cannabidiol
  • Sponsor:Wageningen Research Stichting

Study on Long-Term Safety of Soticlestat for Patients with Dravet or Lennox-Gastaut Syndromes

InvestigationalNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:0–17 years · 18–64 years
  • Substances:Soticlestat
  • Sponsor:Takeda Development Center Americas Inc.
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