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Istituto Oncologico Veneto

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Italy Via Gattamelata 64, 35128 Padua, Italy

  • 157 trials recruiting
  • Non-small cell lung cancer · Breast cancer · Colorectal cancer metastatic
  • Adults and children

About Specializations

Istituto Oncologico Veneto in Padua, Italy specialises in clinical trials of conditions such as Non-small cell lung cancer, Breast cancer, Colorectal cancer metastatic, Malignant melanoma, and other specialisations. This site conducts important research.

Main research areas of the site

Non-Small Cell Lung Cancer (NSCLC)

The medical center is at the forefront of research in Non-Small Cell Lung Cancer (NSCLC), focusing on innovative therapies that target specific genetic markers and immune checkpoints. The center's studies explore the efficacy of novel combinations of immunotherapy and targeted agents to improve patient outcomes.

  • Anti-TIGIT and Anti-PD-L1 Antibodies
  • Combination Therapies with Osimertinib
  • Advanced Immunotherapy Combinations

These efforts contribute significantly to the development of personalized treatment strategies, enhancing progression-free survival and overall survival rates in NSCLC patients.

Colorectal Cancer

Research at the center includes advanced studies on Stage IV Colorectal Cancer, with a focus on adjuvant therapies that aim to improve disease-free survival. The center is pioneering approaches that integrate novel therapeutic agents to target residual disease post-surgery.

  • Adjuvant Therapy Innovations
  • Targeted Molecular Therapies

These studies are crucial in advancing the understanding of colorectal cancer management and improving long-term patient outcomes.

Melanoma

The center is actively involved in cutting-edge research on Advanced Melanoma, including studies on brain metastases and PD-1 refractory cases. The focus is on evaluating the safety and efficacy of novel immunotherapy combinations to enhance treatment response rates.

  • Immunotherapy Combinations
  • Brain Metastasis Management

These initiatives are pivotal in developing new therapeutic options for melanoma patients, particularly those with challenging metastatic conditions.

Renal Cell Carcinoma

Research efforts at the center include comprehensive studies on Metastatic Renal Cell Carcinoma, focusing on the efficacy and safety of novel drug combinations. The center is exploring innovative treatment regimens to improve patient survival and quality of life.

  • Combination Immunotherapy
  • Targeted Therapy Approaches

These studies are instrumental in advancing therapeutic strategies for renal cell carcinoma, offering hope for improved patient outcomes.

Breast Cancer

The center is leading research in Hormone Receptor-Positive, HER2-Negative Breast Cancer, focusing on the development of new treatment combinations to enhance progression-free survival. The research aims to provide more effective options for patients with advanced or metastatic disease.

  • Novel Drug Combinations
  • Targeted Therapy Innovations

These efforts are crucial in improving therapeutic outcomes and offering personalized treatment plans for breast cancer patients.

Bladder Cancer

The center's research in Muscle Invasive Bladder Cancer focuses on evaluating the efficacy of novel immunotherapy combinations. The studies aim to improve event-free survival and provide new treatment avenues for patients ineligible for standard chemotherapy.

  • Immunotherapy Advancements
  • Alternative Treatment Strategies

These research initiatives are vital in developing new therapeutic options for bladder cancer patients, particularly those with limited treatment choices.

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Site location
Via Gattamelata 6435128 PaduaItaly
Recruiting now
157 trials
Conditions studied
166
Partner status
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405 clinical trials

A study of loxo-435, enfortumab vedotin, and pembrolizumab in adults with advanced or metastatic bladder cancer

Registered drug
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Enfortumab Vedotin
  • Sponsor:Eli Lilly & Co.

Study of sotorasib, panitumumab and a drug combination for patients with metastatic colorectal cancer with KRAS p.G12C mutation.

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years
  • Substances:Bevacizumab
  • Sponsor:Amgen Inc.

Phase III Randomized Study of Rilvegostomig vs. Pembrolizumab with Platinum-based Chemotherapy in PD-L1 Expressing Metastatic Squamous NSCLC

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Astrazeneca AB

A study comparing XL092 versus everolimus in patients with previously treated advanced or metastatic neuroendocrine tumors

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Everolimus
  • Sponsor:Exelixis Inc.

A Study of Ivonescimab Combined with Fluorouracil, Folinic Acid, and Oxaliplatin Compared to Bevacizumab for Patients with Metastatic Colorectal Cancer

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Summit Therapeutics Inc.

Study of personalized treatment using drug combination therapy for young women with early stage hormone receptor-positive breast cancer based on gene expression testing

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years
  • Substances:Anastrozole
  • Sponsor:Unicancer

Study of Ifinatamab Deruxtecan and Chemotherapy for Patients with Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Docetaxel
  • Sponsor:Daiichi Sankyo Inc.

Breast cancer

Recruiting

Study on the Safety and Effectiveness of Trastuzumab Deruxtecan vs. Palbociclib-Based Drug Combination for Advanced HR-Positive, HER2-Low Breast Cancer Patients

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Abemaciclib
  • Sponsor:Medica Scientia Innovation Research S.L.

Breast cancer+1

Recruiting

Study on the Effectiveness of GP2 and Sargramostim for HER2 Positive Breast Cancer Patients with Residual Disease or High-Risk After Standard Therapy

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Sargramostim
  • Sponsor:Greenwich LifeSciences Inc.

Study of Dostarlimab After Chemoradiation for Adults with Advanced Unresected Head and Neck Cancer

Registered drug
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Dostarlimab
  • Sponsor:Glaxosmithkline Research & Development Limited

Study on Long-term Safety of Nivolumab and Drug Combination for Cancer Patients from Previous BMS Trials

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Study of Tucatinib, Trastuzumab, and mFOLFOX6 for Patients with HER2+ Metastatic Colorectal Cancer

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Seagen Inc.
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