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Istituti Clinici Scientifici Maugeri In Forma Abbreviata Istituti Clinici Scientifici Maugeri O Anche Ics Maugeri O Maugeri S.p.A. Sb

Research site

Italy Via Generale Nicola Bellomo 73/75, 70124 Bari, Italy

  • Cardiac failure · Asthma
  • Adults and children

About Specializations

Istituti Clinici Scientifici Maugeri In Forma Abbreviata Istituti Clinici Scientifici Maugeri O Anche Ics Maugeri O Maugeri S.p.A. Sb in Bari, Italy specialises in clinical trials of conditions such as Cardiac failure, Asthma, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases

The Istituti Clinici Scientifici Maugeri cardiology department in Bari is conducting research focused on heart failure, especially forms with preserved or mildly reduced ejection fraction, and the impact of renal dysfunction and systemic inflammation on outcomes.

  • Evaluation of a dual SGLT2‑inhibitor and mineralocorticoid‑receptor antagonist therapy (balcinrenone/dapagliflozin) versus dapagliflozin alone.
  • Assessment of a monthly anti‑inflammatory monoclonal antibody (ziltivekimab) added to standard care.
  • Investigation of heart failure with mildly reduced ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF).
  • Study of patients with chronic heart failure and concurrent kidney impairment.

The trials aim to reduce cardiovascular death and heart‑failure events by testing whether the new combination drug or the anti‑inflammatory antibody can improve outcomes compared with existing therapy, offering potential advances for patients with complex heart‑failure phenotypes.

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Site location
Via Generale Nicola Bellomo 73/7570124 BariItaly
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Recruiting now
no trials
Conditions studied
2

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Ongoing trials

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3 clinical trials

Cardiac failure

Not recruiting

A study comparing ziltivekimab to placebo in patients with heart failure with mildly reduced or preserved ejection fraction and inflammation

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Ziltivekimab
  • Sponsor:Novo Nordisk A/S

Asthma

Not recruiting

Study on the Effectiveness and Safety of Budesonide, Glycopyrronium, and Formoterol Inhaler for Adults and Adolescents with Severe Asthma Not Well Controlled

Registered drug
Countries:ItalyItaly
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:AstraZeneca AB

Cardiac failure

Not recruiting

Study on Balcinrenone and Dapagliflozin for Patients with Heart Failure and Kidney Problems

Registered drug
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Balcinrenone
  • Sponsor:AstraZeneca AB
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