Hospital Universitario San Juan De Alicante

At Hospital Universitario San Juan De Alicante, a major share of the clinical research portfolio focuses on Neoplasms, especially breast cancer. Trials are exploring new treatment options for early, advanced, HER2-positive, HER2-low, and hormone receptor-positive disease, with the aim of improving survival, delaying progression, and refining treatment choices for patients with difficult-to-treat cancers.

• Advanced triple negative breast cancer and early breast cancer
• HER2-positive, HER2-low, and HR-positive / HER2-negative breast cancer
• Brain metastases and metastatic breast cancer
• Testing newer targeted and immunotherapy-based approaches

This work reflects a strong interest in evaluating therapies that may be more effective than current standard options for breast cancer.

The site’s Allergology department is actively involved in research on immune system diseases and respiratory tract diseases, with a clear focus on allergic rhinitis, rhinoconjunctivitis, and asthma. These studies are designed to assess allergen immunotherapy and other treatments that may better control symptoms and improve day-to-day quality of life.

• Allergic rhinoconjunctivitis with or without controlled asthma
• Moderate-to-severe allergic rhinitis and pollen-related symptoms
• House dust mite and grass allergy treatment
• Evaluating symptom relief and improved allergy control

Research at this hospital is helping advance more personalized care for people living with persistent allergy-related conditions.

Another important area of research covers cardiovascular diseases and nutritional and metabolic diseases. Trials at the site are studying conditions such as myocardial infarction, spontaneous coronary artery dissection, familial hypercholesterolemia, and type 2 diabetes, with the goal of improving prevention, recovery, and long-term disease control.

• Heart attack and coronary artery complications
• High cholesterol in children and inherited lipid disorders
• Diabetes management in patients with renal impairment
• Assessing better prevention and treatment strategies

These studies support more effective care for patients with chronic cardiometabolic conditions and acute cardiovascular events.

The research portfolio also includes hemic and lymphatic diseases and complex immune-related disorders. At Hospital Universitario San Juan De Alicante, trials are investigating haemophilia A and chronic inflammatory rheumatic diseases, while also looking at ways to reduce cardiovascular risk in people with inflammatory conditions.

• Haemophilia A with factor VIII inhibitors
• Rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, and lupus
• Cardiovascular prevention in inflammatory disease
• Improving bleeding control and long-term risk management

The overall aim is to test better approaches for managing both disease activity and related complications in these patients.

The site is also involved in studies on pathological conditions, signs and symptoms such as septic shock. This research is focused on improving emergency and intensive care treatment, with the goal of supporting survival and reducing the need for prolonged organ support in severely ill patients.

• Septic shock and early resuscitation care
• Testing tailored treatment strategies in critical illness
• Improving short-term outcomes in intensive care
• Evaluating more effective supportive care approaches

These trials contribute to better decision-making in critical care medicine for patients with life-threatening infection-related complications.

Beyond disease-specific treatment studies, the site participates in research on analytical, diagnostic and therapeutic techniques and equipment as well as broader physiological processes. This includes efforts to improve how patients are identified, monitored, and matched to the most appropriate therapy across several specialties.

• Using diagnostic tools to refine cardiovascular risk assessment
• Monitoring treatment response in diabetes and allergy care
• Supporting more precise patient selection for therapy
• Strengthening evidence for everyday clinical decision-making

The research environment at this Spanish hospital combines treatment-focused trials with studies that aim to improve diagnosis and patient stratification.