Hospital Universitario Infanta Sofía

At Hospital Universitario Infanta Sofía, the Hematología team is involved in studies focused on hemic and lymphatic diseases and neoplasms, with a strong emphasis on improving outcomes for people with acute myeloid leukemia, newly-diagnosed multiple myeloma, and metastatic castration-resistant prostate cancer. These trials are designed to test new treatment approaches and compare them with current standards of care.

• New treatment strategies for acute myeloid leukemia and other blood cancers
• Research in newly-diagnosed multiple myeloma aimed at deepening response to therapy
• Studies in advanced solid tumors such as metastatic castration-resistant prostate cancer

The site also contributes to research in breast cancer, endometrial cancer, ovarian cancer, and bladder cancer, reflecting a broad oncology portfolio.

Clinical trials at this site address cardiovascular diseases and blood-clotting disorders, including acute heart failure, acute pulmonary embolism, deep vein thrombosis, hypertension, and atherosclerotic cardiovascular disease. The main goal is to evaluate therapies that may improve symptom control, reduce complications, and lower long-term cardiovascular risk.

• Studies testing better care for acute pulmonary embolism and thrombolysis of symptomatic proximal vein thrombosis
• Research in heart failure focused on improving decongestion and recovery
• Trials in hypertension and high cardiovascular risk aimed at preventing major events

Work in this area includes efforts to improve treatment effectiveness for patients with established vascular disease and to support safer, more personalized cardiovascular care.

The site is active in immune system diseases and nervous system diseases, with studies in systemic lupus erythematosus, ANCA-associated vasculitis, and generalized myasthenia gravis. These trials aim to assess new therapies that may better control disease activity, reduce flare-ups, and improve daily functioning.

• Research in systemic lupus erythematosus to improve disease control and safety
• Studies in generalized myasthenia gravis focused on muscle strength and symptom relief
• Trials in ANCA-associated vasculitis evaluating treatment safety and effectiveness

This therapeutic area highlights a strong interest in chronic inflammatory conditions where more precise and better-tolerated treatments are needed.

Research at Hospital Universitario Infanta Sofía also covers skin and connective tissue diseases, respiratory tract diseases, and eye diseases. Trials include atopic dermatitis, allergic rhinoconjunctivitis, and non-infectious uveitis, with the purpose of improving symptom control and testing targeted immunotherapy approaches.

• Studies in atopic dermatitis evaluating better control of skin inflammation and itching
• Allergy research in allergic rhinoconjunctivitis and pollen sensitization
• Eye disease trials in non-infectious uveitis to improve inflammatory control

These projects reflect a broader effort to refine treatment for common allergic and inflammatory conditions that affect quality of life.

The clinical trial portfolio also includes nutritional and metabolic diseases and musculoskeletal diseases, along with selected nervous system diseases. Key areas include hypercholesterolemia, overweight or obesity and knee osteoarthritis, early Parkinson’s disease, and myotonic dystrophy type 1, with studies aimed at improving disease management and patient outcomes.

• Trials in hypercholesterolemia and cardiovascular risk reduction
• Research in overweight or obesity and knee osteoarthritis focused on weight control and pain relief
• Studies in early Parkinson’s disease and myotonic dystrophy type 1 exploring symptom improvement

This mix of research shows a broad interest in chronic conditions where better long-term treatment options are still needed.