Hospital Universitario De Cruces

At Hospital Universitario De Cruces, clinical research in neoplasms focuses on improving outcomes for people with early breast cancer, prostate cancer, colon cancer, pleural mesothelioma, acute myeloid leukemia, and neuroblastoma. These studies are designed to test new treatment strategies, reduce recurrence, and strengthen long-term disease control.

• Breast cancer recurrence prevention and long-term follow-up in early-stage disease
• Treatment approaches for high-risk and metastatic prostate cancer
• New options for resectable colon cancer, pleural mesothelioma, and AML
• Therapies for pediatric relapsed/refractory solid tumours

Much of this work aims to evaluate whether newer cancer therapies can improve survival, delay progression, and support better quality of life.

Research in nervous system diseases includes studies on Parkinson’s disease, Huntington’s disease, multiple sclerosis, and acute stroke. The goal is to assess treatments that may slow disability, improve recovery, and better manage long-term neurological decline.

• New therapies for movement symptoms in Parkinson’s disease
• Safety and effectiveness research in Huntington’s disease
• Long-term treatment evaluation in relapsing and progressive multiple sclerosis
• Stroke recovery studies aimed at improving reperfusion-related outcomes

This area reflects a strong interest in both chronic neurodegenerative conditions and urgent brain injury care.

The site also studies eye diseases, especially thyroid eye disease and uveitic macular edema. These trials are focused on evaluating treatments that may reduce inflammation, improve vision-related symptoms, and support eye function over time.

• Treatment research for moderate-to-severe thyroid eye disease
• Studies in uveitic macular edema to assess visual outcomes

These projects aim to improve care for patients with vision-threatening conditions linked to immune and inflammatory disease.

Clinical trials in immune system diseases and skin and connective tissue diseases include moderate to severe plaque psoriasis and chronic rhinosinusitis. The research is intended to test new therapies that may better control inflammation and improve daily symptoms.

• Studies in pediatric plaque psoriasis to evaluate safety and symptom control
• Research in chronic rhinosinusitis aimed at improving quality of life

These trials reflect a broader effort to refine treatment options for long-standing inflammatory disorders.

Another major research focus at Hospital Universitario De Cruces is on nutritional and metabolic diseases, congenital and hereditary disorders, and musculoskeletal diseases. Studies include gout with hyperuricemia, ornithine transcarbamylase deficiency, and osteogenesis imperfecta, with the aim of improving disease control and long-term safety of treatment.

• Therapies for gout to lower uric acid more effectively
• Long-term research in OTC deficiency and other inherited conditions
• Treatment evaluation in osteogenesis imperfecta to reduce fractures

These studies address conditions that often require ongoing management across childhood and adulthood.

Trials in female urogenital diseases and pregnancy complications include research on preeclampsia. The purpose is to test preventive strategies that may lower the risk of early delivery and improve maternal-fetal outcomes.

• Prevention-focused research in preeclampsia

This work supports safer pregnancy care through better risk reduction and earlier intervention.

The site contributes to pediatric studies in congenital and hereditary diseases and immune-related prevention, including research on herpes zoster prevention in immunocompromised children and adolescents. These trials are aimed at improving protection, safety, and immune response in vulnerable groups.

• Prevention of herpes zoster in immunocompromised pediatric patients
• Safety and immune response studies in younger age groups

The research supports better preventive care for children with complex medical needs.