Hospital Universitario Basurto

The Hematología department at Hospital Universitario Basurto is active in studies of hematic and lymphatic diseases, with a strong focus on cancers and immune-related blood conditions. Research here includes acute myeloid leukemia, chronic myeloid leukemia, paroxysmal nocturnal hemoglobinuria, and peripheral T-cell lymphoma, reflecting an effort to improve treatment options and long-term disease control.

• Testing new therapies for blood cancers and rare hematologic disorders
• Evaluating treatment effectiveness in leukemia and lymphoma
• Studying immune-based approaches for blood-related diseases

These trials aim to expand options for patients with complex blood diseases while supporting safer and more effective care.

One of the most prominent research areas at this site is neoplasms, especially breast cancer. Trials cover early and advanced disease, including HER2-positive, HER2-negative, and triple-negative breast cancer, as well as locoregional recurrence and metastatic disease. The research is centered on improving outcomes with newer cancer therapies and refining treatment strategies for different tumor subtypes.

• Testing targeted and antibody-based treatments for breast cancer
• Evaluating therapies for high-risk, recurrent, and metastatic disease
• Studying ways to improve survival and reduce relapse

At Hospital Universitario Basurto, this oncology portfolio shows a strong commitment to personalized cancer care.

Clinical research in respiratory tract diseases includes a substantial number of studies in non-small cell lung cancer and small cell lung cancer. The trials address newly diagnosed, locally advanced, and metastatic disease, with attention to biomarker-driven subgroups such as KRASG12C and HER2 alterations. The overall goal is to improve response rates, disease control, and long-term outcomes in lung cancer.

• Testing new immunotherapy and targeted treatment options
• Improving care for advanced and resectable lung cancer
• Exploring biomarker-guided approaches to treatment selection

This area also includes studies designed to strengthen treatment effectiveness after surgery or chemoradiotherapy.

The site is also highly active in immune system diseases and phenomena and processes related to inflammation. Research includes rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, Sjögren’s syndrome, and giant cell arteritis. These studies are focused on reducing disease activity, easing symptoms, and improving daily functioning for people with chronic autoimmune conditions.

• Evaluating new immune-modulating therapies
• Measuring symptom relief and disease control
• Studying treatment options for difficult-to-manage inflammatory disorders

The research portfolio also includes related conditions affecting nerves and connective tissue, showing broad expertise in inflammatory disease care.

Research in skin and connective tissue diseases includes studies of atopic dermatitis, chronic inducible urticaria, nummular dermatitis, and allergic rhinoconjunctivitis. These trials are designed to test new treatment approaches, improve long-term symptom control, and support better quality of life for patients with persistent allergic and inflammatory skin conditions.

• Testing therapies for moderate-to-severe eczema and related skin diseases
• Evaluating options for chronic itching and urticaria
• Improving control of allergy-driven symptoms

The dermatology program adds important breadth to the clinical research profile of Hospital Universitario Basurto.

Studies in nervous system diseases and related immune processes include multiple sclerosis, generalized myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy. The main purpose of these trials is to assess new treatments that may help control symptoms, prevent relapses, and preserve neurological function over time.

• Evaluating therapies for autoimmune nerve and muscle disorders
• Assessing long-term disease control in chronic neurological illness
• Supporting research into improved functional outcomes

These investigations reflect a strong interest in immune-mediated neurological disease at the site.

The trial portfolio also spans cardiovascular diseases, nutritional and metabolic diseases, and kidney-related care. Research includes atherosclerotic cardiovascular disease, spontaneous coronary artery dissection, heart failure, type 2 diabetes, and end-stage kidney disease. These studies seek better ways to prevent complications, improve disease management, and evaluate the effectiveness of newer treatments.

• Testing therapies to reduce cardiovascular events and improve heart health
• Studying glucose control in diabetes
• Evaluating care approaches for kidney disease and dialysis-related needs

This area shows a broad interest in chronic disease management and prevention.

Another important field is male urogenital diseases and female urogenital diseases, especially bladder cancer, upper tract urothelial carcinoma, and prostate cancer. The studies are aimed at improving treatment effectiveness, supporting surgery-related decision-making, and exploring better options for patients with recurrent, high-risk, or advanced disease.

• Evaluating new treatments for bladder and urinary tract cancers
• Studying approaches for high-risk non-muscle invasive disease
• Assessing treatment strategies in advanced prostate cancer

The research activity here highlights a strong oncology focus beyond breast and lung cancer.

The site also conducts studies in several additional therapeutic areas, including digestive system diseases, eye diseases, musculoskeletal diseases, hormonal diseases, and virus diseases. Examples include idiopathic pulmonary fibrosis, progressive fibrosing interstitial lung disease, transthyretin amyloidosis, and HIV infections, showing a wide-ranging clinical research program that extends beyond its core hematology expertise.

• Testing treatments for rare and chronic multisystem diseases
• Improving long-term safety and symptom control
• Exploring new options across diverse medical specialties

Across these areas, Hospital Universitario Basurto supports research aimed at practical improvements in patient care.