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Hospital Universitari Dexeus Grupo Quironsalud

Research site

Spain Calle De Sabino Arana 5-19, 08028 Barcelona, Spain

  • 50 trials recruiting
  • Non-small cell lung cancer · Breast cancer · Non-small cell lung cancer metastatic
  • Adults and children

About Specializations

Hospital Universitari Dexeus Grupo Quironsalud in Barcelona, Spain specialises in clinical trials of conditions such as Non-small cell lung cancer, Breast cancer, Non-small cell lung cancer metastatic, Triple negative breast cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Medical Oncology at Hospital Universitari Dexeus Grupo Quironsalud

Clinical research here is strongly focused on neoplasms, with a broad mix of studies in breast cancer, non-small cell lung cancer, melanoma, and other advanced solid tumors. Many trials aim to test new treatment options, compare them with current standards, and improve outcomes for people with difficult-to-treat cancers.

  • Studies in breast cancer include hormone receptor-positive, HER2-negative disease, HER2-positive disease, and triple-negative breast cancer, often evaluating whether newer therapies can improve survival and disease control.
  • A major research focus is non-small cell lung cancer, including EGFR-, KRAS-, RET-, MET-, and HER2-driven subtypes, with trials designed to refine targeted treatment and immunotherapy strategies.
  • There is also active work in melanoma, classical Hodgkin lymphoma, and broader solid tumors, exploring more effective ways to treat advanced or resectable disease.

Across the site’s portfolio, investigators are also studying supportive and specialized care in areas such as female reproductive health, pregnancy complications, and infertility, showing a wider interest in improving both cancer care and related patient outcomes.

Research in lung cancer and thoracic oncology

This site has a particularly large number of trials in advanced non-small cell lung cancer and related thoracic cancers. The research is centered on testing targeted therapies, immunotherapy combinations, and perioperative approaches to improve response rates, survival, and long-term disease control.

  • Trials in EGFR-mutated, KRAS G12C-mutated, RET fusion-positive, HER2-altered, and MET-driven lung cancer are evaluating precision medicine approaches for specific tumor profiles.
  • Several studies focus on resectable or early-stage lung cancer, aiming to strengthen treatment before or after surgery and reduce the risk of recurrence.
  • Other projects examine small cell lung cancer and metastatic disease, with the goal of improving outcomes when standard options are limited.

At Hospital Universitari Dexeus Grupo Quironsalud, this area reflects a major effort to match each patient’s tumor biology with more precise and effective treatment strategies.

Breast cancer and hormone-driven tumors

Another major research stream involves breast neoplasms, especially advanced and early-stage disease with hormone receptor-positive, HER2-negative, HER2-positive, and triple-negative subtypes. The trials are designed to improve treatment effectiveness, reduce recurrence, and explore better options after standard therapies.

  • Studies in HER2-positive breast cancer are assessing new treatment sequences and combinations to strengthen response in both early and metastatic disease.
  • Research in HR-positive/HER2-negative breast cancer is focused on overcoming resistance and improving progression-free survival in advanced cases.
  • Trials in triple-negative breast cancer aim to expand options for one of the most challenging breast cancer subtypes.

These studies also include work on symptom management and quality of life, such as reducing vasomotor symptoms linked to endocrine therapy.

Melanoma, hematologic cancers, and other advanced malignancies

The research portfolio also includes studies in melanoma, advanced classical Hodgkin lymphoma, and a range of advanced solid tumors. These trials are typically aimed at improving immune-based treatment approaches, expanding options for patients with recurrent disease, and identifying more effective combinations than current standards.

  • In melanoma, the focus is on perioperative and adjuvant strategies that may lower the chance of relapse after surgery.
  • In Hodgkin lymphoma, research is evaluating new frontline treatment approaches to improve disease control.
  • Broader solid tumor studies are exploring new therapies for patients whose cancers have progressed or no longer respond to available treatments.

These efforts show the site’s interest in both disease-specific innovation and more general cancer treatment development.

Women’s health, pregnancy, and reproductive medicine

Beyond oncology, the site is also involved in clinical trials related to female urogenital diseases, pregnancy complications, and infertility. These studies address common but important conditions that affect reproductive health, comfort, and pregnancy outcomes.

  • Research in infertility is examining ways to support assisted reproductive care and improve embryo-related outcomes.
  • Trials in preeclampsia are focused on prevention and maternal-fetal safety during pregnancy.
  • Studies in genitourinary syndrome of menopause are evaluating better symptom relief and quality of life for women after menopause.

These projects broaden the clinical research profile of Hospital Universitari Dexeus Grupo Quironsalud beyond cancer care, while still emphasizing practical improvements for patients.

Supportive care and specialized therapies

Some studies at this site focus on supportive and highly specialized medical care, including conditions linked to hormonal disease, immune system disorders, and respiratory tract disease. The purpose of these trials is often to improve symptom control, safety, and everyday functioning alongside disease treatment.

  • Studies in menopause-related symptoms and heartburn or reflux aim to improve comfort and tolerability in everyday care.
  • Research in achondroplasia and bronchopulmonary dysplasia reflects interest in rare or specialized conditions affecting growth and early-life health.
  • Other work explores cellular therapies and regenerative approaches for selected patient groups.

This mix of research highlights a site that combines advanced oncology trials with broader clinical questions relevant to women’s health, pediatrics, and supportive treatment.

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Site location
Calle De Sabino Arana 5-1908028 BarcelonaSpain
Recruiting now
50 trials
Conditions studied
83

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
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Quick filters

129 clinical trials

A study to evaluate the safety and effectiveness of HLX43 in patients with advanced non-small cell lung cancer

InvestigationalNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:HLX43
  • Sponsor:Shanghai Henlius Biotech Inc.

Breast cancer

Recruiting

Study on the Safety and Effectiveness of Trastuzumab Deruxtecan vs. Palbociclib-Based Drug Combination for Advanced HR-Positive, HER2-Low Breast Cancer Patients

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Abemaciclib
  • Sponsor:Medica Scientia Innovation Research S.L.

A Study of Setidegrasib with Chemotherapy Drug Combination as First‑Line Treatment in Adults with KRAS G12D‑mutated Metastatic Pancreatic Cancer

Investigational
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:ASP3082
  • Sponsor:Astellas Pharma Global Development Inc.

Study of LY3537982, pembrolizumab, and a drug combination for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drug
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Eli Lilly & Co.

Neoplasm

Recruiting

Long‑term Safety of Adagrasib with Drug Combination in Adults with Solid Tumors

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Adagrasib
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Azenosertib versus drug combination in platinum‑resistant high‑grade serous ovarian, fallopian tube or primary peritoneal cancer

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Azenosertib
  • Sponsor:K-Group Beta Inc.

Safety and Tolerability of Alisertib Sodium and Paclitaxel in Patients with Small Cell Lung Cancer (Phase 2 Study)

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Alisertib Sodium
  • Sponsor:Puma Biotechnology Inc.

EIK1001, Pembrolizumab, and Chemotherapy for Stage 4 Non-Small Cell Lung Cancer in Patients with Stage 4 Non-Small Cell Lung Cancer

Registered drug
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:Eikon Therapeutics Inc.

Phase 3 Study of LY4170156 (Sofetabart Mipitecan) with drug combination in platinum‑resistant and platinum‑sensitive ovarian cancer patients

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Eli Lilly & Co.

Breast cancer+1

Recruiting

Zanidatamab, tucatinib, capecitabine or eribulin mesylate in HER2-positive advanced breast cancer in adults

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Medica Scientia Innovation Research S.L.

Breast cancer+1

Recruiting

Maintenance Therapy Study of Inavolisib with Pertuzumab and Trastuzumab in Patients with HER2‑Positive, PIK3CA‑Mutated Locally Advanced or Metastatic Breast Cancer

Registered drug
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:F. Hoffmann-La Roche AG

A study of palazestrant and ribociclib compared to letrozole and ribociclib for patients with advanced ER+ HER2- breast cancer

Registered drug
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Letrozole
  • Sponsor:Olema Pharmaceuticals Inc.
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