Rare diseases
Investigational molecules
Locations
12 Avenue Paul Vaillant Couturier, 94804 Villejuif, France
Hospital Paul Brousse in Villejuif, France specialises in clinical trials of conditions such as Hepatocellular carcinoma, Primary biliary cholangitis, Pancreatic carcinoma, Pancreatic carcinoma metastatic, and other specialisations. This site conducts important research.
The department advances innovative therapeutic technologies by testing novel antibody combinations, targeted delivery systems, and emerging biologics to improve patient outcomes.
Hospital Paul Brousse in Villejuif, France, supports 11 clinical trials led by 28 investigators, fostering cutting‑edge research in therapeutic innovation.
Researchers focus on liver‑related conditions, addressing diseases such as Primary Biliary Cholangitis and Alpha‑1 Antitrypsin Deficiency to alleviate symptoms and limit progression.
The site’s multidisciplinary team conducts trials that integrate gastroenterology expertise with advanced diagnostic tools.
The oncology program evaluates therapies for liver malignancies, including Hepatocellular Carcinoma and Advanced Biliary Tract Cancers, aiming to extend survival and improve quality of life.
Collaborative studies at Hospital Paul Brousse bring together surgical, radiologic, and medical oncology expertise.
Clinical investigations target rare metabolic liver disorders such as Urea Cycle Disorders and Crigler‑Najjar Syndrome, exploring cell‑based and gene‑silencing approaches.
These studies integrate metabolic genetics with hepatology to address unmet therapeutic needs.
The psychiatry division investigates treatments for Behavioral Addictions such as gambling, sexual, and food compulsions, evaluating medications that reduce craving intensity.
The trials aim to expand therapeutic options for patients struggling with compulsive behaviors.
A broad portfolio of multicentre investigations supports cross‑disciplinary studies, from safety profiling to biomarker discovery, enhancing overall clinical knowledge.
Hospital Paul Brousse leverages its extensive investigator network to conduct diverse and impactful research.
Clinical trials currently enrolling participants at this site.
Study of Elafibranor for Adults with Primary Biliary Cholangitis
FranceStudy on the Long-term Safety and Efficacy of Pembrolizumab and Lenvatinib for Patients with Advanced Tumors
FranceA Phase 2/3 Randomized Double‑Blind Study of Inebilizumab for Safety and Tolerability in Patients with Autoimmune Hepatitis
FranceComparing Daraxonrasib Alone or Combined with Gemcitabine and Paclitaxel Albumin‑Bound vs Standard Chemotherapy in Patients with Metastatic Pancreatic Adenocarcinoma
FranceA Phase 3 Study of Efimosfermin Alfa to Assess Safety and Tolerability in Adults with F2‑F3 Stage Metabolic Dysfunction‑Associated Steatohepatitis (MASH)
FranceSafety and Efficacy of Efimosfermin Alfa in Participants with Biopsy‑Confirmed F2‑ or F3‑Stage Metabolic Dysfunction‑Associated Steatohepatitis (MASH)
FranceA study of daraxonrasib (RMC-6236) compared to observation in patients with resected pancreatic cancer following chemotherapy
FranceA study to evaluate the effectiveness and safety of vamifeport in adults with hereditary hemochromatosis
FranceA study to evaluate the safety and effectiveness of darizmetinib hydrochloride in patients who have had liver surgery due to colon cancer metastases
FranceFranceStudy of Seladelpar Treatment in Patients with Primary Biliary Cholangitis and Compensated Cirrhosis
FranceStudy on Chemotherapy for Patients with Resected Pancreatic Cancer Using FOLFIRINOX and Drug Combination
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