A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis
- Substances:–
Spain- Participants:18–64 years
- Sponsor:Zenas Biopharma (USA) LLC
Rare diseases
Investigational molecules
Locations
Calle Del Doctor Esquerdo 46, 28007 Madrid, Spain
Hospital General Universitario Gregorio Maranon in Madrid, Spain specialises in clinical trials of conditions such as Non-small cell lung cancer, Colorectal cancer metastatic, Breast cancer, Colorectal cancer, and other specialisations. This site conducts important research.
Research at Hospital General Universitario Gregorio Maranon focuses on blood‑related cancers, aiming to improve survival and reduce treatment‑related toxicity.
Additional info: trials test novel targeted agents, cellular therapies and maintenance strategies to achieve deeper remissions.
Investigations target a broad range of solid tumors, evaluating new targeted drugs and combination regimens to extend progression‑free survival.
Additional info: many studies incorporate biomarker‑driven enrollment such as KRAS, EGFR, HER2, and PD‑L1 status.
Trials address immune‑mediated conditions, testing innovative biologics and small molecules to control disease activity.
Additional info: objectives include improving quality of life and reducing flare frequency.
Research explores therapies for heart disease and metabolic disorders, seeking to lower event rates and improve organ function.
Additional info: studies often evaluate anti‑inflammatory or metabolic pathways such as IL‑6 inhibition.
Clinical work includes chronic liver conditions and digestive‑tract cancers, aiming to halt disease progression and alleviate symptoms.
Additional info: endpoints frequently involve liver fibrosis regression and patient‑reported itch scores.
Studies address severe infections and post‑transplant complications, testing antivirals, antibiotics, and immune‑modulating protocols.
Additional info: safety and infection‑control outcomes are primary measures.
Clinical trials currently enrolling participants at this site.
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