Hematologic Malignancies

Research at Hospital General Universitario Gregorio Maranon focuses on blood‑related cancers, aiming to improve survival and reduce treatment‑related toxicity.

  • Acute myeloid leukemia
  • Chronic myeloid leukemia
  • Acute lymphoblastic leukemia
  • Multiple myeloma
  • Mantle cell lymphoma
  • Diffuse large B‑cell lymphoma
  • Myelodysplastic syndromes
  • Chronic lymphocytic leukemia

Additional info: trials test novel targeted agents, cellular therapies and maintenance strategies to achieve deeper remissions.

Solid Tumor Oncology

Investigations target a broad range of solid tumors, evaluating new targeted drugs and combination regimens to extend progression‑free survival.

  • Breast cancer
  • Non‑small cell lung cancer
  • Colorectal cancer
  • Melanoma
  • Gastric cancer
  • Pancreatic ductal adenocarcinoma
  • Renal cell carcinoma
  • Hepatocellular carcinoma
  • Sarcoma

Additional info: many studies incorporate biomarker‑driven enrollment such as KRAS, EGFR, HER2, and PD‑L1 status.

Immunology and Autoimmune Diseases

Trials address immune‑mediated conditions, testing innovative biologics and small molecules to control disease activity.

  • Systemic lupus erythematosus
  • Immune thrombocytopenia
  • Atopic dermatitis
  • Psoriasis
  • Multiple sclerosis
  • Rheumatoid arthritis
  • Inflammatory bowel disease
  • Chronic graft‑versus‑host disease

Additional info: objectives include improving quality of life and reducing flare frequency.

Cardiovascular and Metabolic Research

Research explores therapies for heart disease and metabolic disorders, seeking to lower event rates and improve organ function.

  • Acute myocardial infarction
  • Heart failure with reduced ejection fraction
  • Atherosclerotic cardiovascular disease
  • Type 2 diabetes
  • Metabolic dysfunction‑associated steatohepatitis
  • Hypertension

Additional info: studies often evaluate anti‑inflammatory or metabolic pathways such as IL‑6 inhibition.

Liver and Gastrointestinal Disorders

Clinical work includes chronic liver conditions and digestive‑tract cancers, aiming to halt disease progression and alleviate symptoms.

  • Non‑alcoholic steatohepatitis
  • Primary biliary cholangitis
  • Cholestatic pruritus
  • Hepatitis B
  • Colorectal cancer
  • Gastric adenocarcinoma
  • Biliary tract cancer

Additional info: endpoints frequently involve liver fibrosis regression and patient‑reported itch scores.

Infectious Diseases and Transplant Complications

Studies address severe infections and post‑transplant complications, testing antivirals, antibiotics, and immune‑modulating protocols.

  • COVID‑19
  • Acute graft‑versus‑host disease
  • Cytomegalovirus infection
  • Clostridioides difficile infection
  • Invasive fungal infections
  • Transplant rejection

Additional info: safety and infection‑control outcomes are primary measures.