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Hopital Tenon

Research site

France 4 Rue De La Chine, 75970 Paris, France

  • 52 trials recruiting
  • Non-small cell lung cancer · Breast cancer · Squamous cell carcinoma of head and neck
  • Adults and children

About Specializations

Hopital Tenon in Paris, France specialises in clinical trials of conditions such as Non-small cell lung cancer, Breast cancer, Squamous cell carcinoma of head and neck, Non-small cell lung cancer stage IV, and other specialisations. This site conducts important research.

Main research areas of the site

Oncology

The medical center is at the forefront of oncology research, focusing on innovative treatments for various types of cancer. The center's work in non-small cell lung cancer (NSCLC) is particularly noteworthy, with trials exploring the efficacy of pembrolizumab and lorlatinib in advanced stages. Additionally, the center is pioneering studies in breast cancer, investigating the impact of trastuzumab and pertuzumab in HER2-positive cases.

  • Non-Small Cell Lung Cancer (NSCLC)
  • Breast Cancer
  • Prostate Cancer

Through these studies, the center contributes significantly to the development of targeted therapies and personalized medicine approaches, enhancing treatment outcomes and patient quality of life.

Immunology

In the realm of immunology, the center is advancing the understanding and treatment of autoimmune and inflammatory diseases. Research on ANCA vasculitis and eosinophilic granulomatosis with polyangiitis is leading to new insights into disease mechanisms and potential therapeutic interventions.

  • ANCA Vasculitis
  • Eosinophilic Granulomatosis with Polyangiitis
  • Chronic Inducible Urticaria

The center's work in this field is crucial for developing novel treatments that can modulate the immune system more effectively, offering hope for patients with chronic and debilitating conditions.

Nephrology

The center is a leader in nephrology research, particularly in the study of IgA nephropathy and lupus nephritis. Trials involving sibeprenlimab and ravulizumab are exploring new avenues for managing these complex kidney diseases.

  • IgA Nephropathy
  • Lupus Nephritis
  • End-Stage Renal Disease

By focusing on these areas, the center is contributing to the development of therapies that aim to preserve kidney function and improve patient outcomes in chronic kidney diseases.

Infectious Diseases

Research in infectious diseases at the center is making significant strides, particularly in the treatment of HIV and co-infections. Studies on broadly neutralizing antibodies and novel antiretroviral therapies are paving the way for improved management of HIV.

  • HIV
  • HIV-HBV Co-infection
  • Familial Mediterranean Fever

The center's efforts in this domain are vital for advancing therapeutic strategies that enhance viral suppression and improve the quality of life for individuals living with chronic infections.

Respiratory Medicine

In respiratory medicine, the center is conducting groundbreaking research on conditions such as idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease (COPD). Trials are evaluating the efficacy of novel therapeutic approaches to manage and treat these challenging respiratory conditions.

  • Idiopathic Pulmonary Fibrosis
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Non-Small Cell Lung Cancer (NSCLC)

Through these initiatives, the center is contributing to the development of therapies that aim to improve lung function and patient quality of life in chronic respiratory diseases.

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Site location
4 Rue De La Chine75970 ParisFrance
Recruiting now
52 trials
Conditions studied
103

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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136 clinical trials

Phase 3 Study of Enpatoran in Patients with Active Cutaneous Lupus Erythematosus (with or without Systemic Disease)

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Merck Healthcare KGaA

Effectiveness and Safety of Pegcetacoplan in Patients with C3 Glomerulopathy or Primary Immune Complex Membranoproliferative Glomerulonephritis

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Pegcetacoplan
  • Sponsor:Swedish Orphan Biovitrum AB (publ)

Comparing sotorasib and pembrolizumab with chemotherapy for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Amgen Inc.

A study of ficerafusp alfa and nivolumab in patients with head and neck cancer who did not respond to platinum-based chemotherapy.

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Ficerafusp alfa
  • Sponsor:Groupe Oncologie Radiotherapie Tete Cou

Evaluation of Lymphocyte-Sparing Radiotherapy and All-Trans Retinoic Acid in Lateralized Oropharyngeal, Laryngeal, and Hypopharyngeal Squamous Cell Carcinoma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Cetuximab
  • Sponsor:Centre Leon Berard

Study comparing datopotamab deruxtecan with or without durvalumab to chemotherapy with pembrolizumab for patients with triple-negative breast cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:AstraZeneca AB

Study of ivonescimab alone or with ligufalimab versus pembrolizumab for patients with recurrent or metastatic head and neck squamous cell cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Ivonescimab
  • Sponsor:Groupe Oncologie Radiotherapie Tete Cou

A Study Comparing PF-08046054 to Docetaxel in Adults with Previously Treated PD-L1 Positive Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Docetaxel
  • Sponsor:Pfizer Inc.

Study of ribociclib with or without chemotherapy for patients with hormone receptor positive, HER2 negative early breast cancer at intermediate risk

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:Unicancer

Prostate cancer

Recruiting

A study of saruparib with radiotherapy and hormone therapy for men with high-risk prostate cancer who have a BRCA gene mutation

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone Acetate
  • Sponsor:AstraZeneca AB

Study of lidocaine to reduce opioid use in patients with sickle cell disease experiencing severe pain crisis

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:Centre Hospitalier Universitaire De Nantes

Study of trastuzumab deruxtecan with pembrolizumab versus platinum chemotherapy with pembrolizumab for patients with untreated HER2-positive non-small cell lung cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Daiichi Sankyo Inc.
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