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Hopital Prive Jean Mermoz

Research site

France 55 Avenue Jean Mermoz, 69008 Lyon, France

  • 49 trials recruiting
  • Colorectal cancer metastatic · Hormone receptor positive HER2 negative breast cancer · Breast cancer metastatic
  • Adult patients

About Specializations

Hopital Prive Jean Mermoz in Lyon, France specialises in clinical trials of conditions such as Colorectal cancer metastatic, Hormone receptor positive HER2 negative breast cancer, Breast cancer metastatic, Breast cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Non-Small Cell Lung Cancer (NSCLC)

The medical center is at the forefront of research in Non-Small Cell Lung Cancer, focusing on innovative maintenance therapies post-chemotherapy. The center's work aims to enhance the efficacy of treatments like pembrolizumab, offering new hope for patients with advanced stages of this disease.

  • Maintenance therapies
  • Immunotherapy advancements
  • Personalized treatment approaches

Through rigorous clinical trials, the center is contributing to the development of personalized medicine strategies that could significantly improve patient outcomes.

Breast Cancer

Specializing in ER-positive and HER2-negative breast cancer, the center is pioneering studies on the efficacy of combination therapies involving durvalumab, olaparib, and fulvestrant. These efforts are crucial in advancing treatment options for patients with specific genetic profiles.

  • Combination therapy efficacy
  • Genetic profiling in treatment
  • Progression-free survival improvements

The center's research is instrumental in tailoring therapies to individual genetic markers, potentially transforming the standard of care for breast cancer patients.

Pancreatic Fistula Prevention

In the realm of pancreatic surgery, the center is exploring the use of intrapapillary botulinum toxin injections to prevent postoperative pancreatic fistulas. This innovative approach could lead to significant reductions in surgical complications.

  • Postoperative complication reduction
  • Innovative surgical techniques
  • Botulinum toxin applications

By focusing on preventive measures, the center aims to enhance recovery and quality of life for patients undergoing pancreatic surgery.

Anal Squamous Cell Carcinoma

The center is conducting pivotal research on locally advanced anal squamous cell carcinoma, comparing induction chemotherapy followed by chemoradiotherapy to standard treatments. This work is vital in improving survival rates and treatment efficacy.

  • Induction chemotherapy strategies
  • Comparative treatment efficacy
  • Survival rate enhancement

Through these studies, the center is contributing to the optimization of treatment protocols for anal cancer, potentially setting new standards in oncological care.

Biliary Cancer

Focusing on advanced biliary cancer, the center is evaluating maintenance treatments targeting actionable genetic mutations. This research is crucial for developing more effective, personalized treatment plans for patients with this challenging cancer type.

  • Targeted maintenance therapies
  • Genetic mutation targeting
  • Personalized treatment development

The center's efforts are paving the way for more precise and effective interventions in biliary cancer, potentially improving patient survival and quality of life.

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Site location
55 Avenue Jean Mermoz69008 LyonFrance
Recruiting now
49 trials
Conditions studied
63

More sites in LyonFrance

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
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Quick filters

95 clinical trials

Phase 3 Study of atebimetinib with gemcitabine and paclitaxel versus gemcitabine and paclitaxel in patients with metastatic pancreatic cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Paclitaxel

Study of sotorasib, panitumumab and a drug combination for patients with metastatic colorectal cancer with KRAS p.G12C mutation.

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Bevacizumab
  • Sponsor:Amgen Inc.

Randomized Study of INCB161734 Plus Standard Chemotherapy Drug Combination in Untreated KRAS G12D Metastatic Pancreatic Ductal Adenocarcinoma Patients

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Incyte Corp.

Evaluating the use of capecitabine, oxaliplatin, fluorouracil, folinic acid, and irinotecan to personalize chemotherapy for patients with stage III colorectal cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Unicancer

Study of ribociclib with or without chemotherapy for patients with hormone receptor positive, HER2 negative early breast cancer at intermediate risk

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:Unicancer

A Study of Puxitatug Samrotecan Compared to Chemotherapy for Patients with Advanced Endometrial Cancer After Previous Platinum and Immunotherapy Treatment

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:AZD8205
  • Sponsor:AstraZeneca AB

Breast cancer+2

Recruiting

A Study Comparing RLY-2608 and Fulvestrant with Capivasertib and Fulvestrant for Patients with PIK3CA-Mutant Hormone Receptor Positive, HER2-Negative Advanced Breast Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Capivasertib
  • Sponsor:Relay Therapeutics Inc.

A study comparing trifluridine, tipiracil, and fruquintinib versus trifluridine and tipiracil alone for patients with metastatic stomach or esophageal cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Fruquintinib
  • Sponsor:Fondation Franc.Cancerologie Digestive

Testing sacituzumab govitecan and trastuzumab deruxtecan in alternating pattern for patients with HER2-low triple-negative breast cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Sacituzumab Govitecan
  • Sponsor:Unicancer

Study of bevacizumab and trifluridine combination given bi-weekly to reduce severe neutropenia in patients with metastatic colorectal cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Association Gercor

Study of FOLFOX or FOLFIRI chemotherapy with fruquintinib or bevacizumab as second-line treatment for patients with metastatic colorectal cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Fondation Franc.Cancerologie Digestive

Treatment with trastuzumab deruxtecan, capecitabine and bevacizumab for patients with HER2-positive metastatic colorectal cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Fondazione GONO G.I.
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