Hamburg University

The Hamburg University Department of Chemistry conducts studies that evaluate new injection devices and visual assessment methods for facial aesthetic conditions such as glabellar lines and forehead wrinkles, focusing on safety and precise measurement.

• Safety and tolerability of novel botulinum toxin formulations
• Evaluation of diffusion characteristics in facial muscles
• Development of live visual assessment tools for treatment outcomes
• Standardized skin and sweating tests for diagnostic accuracy

This work aims to improve diagnostic precision and equipment performance for non‑invasive cosmetic therapies.

Clinical trials at the site assess innovative therapeutic agents, including IPN10200 and NT 201, for treating moderate to severe facial lines and platysma prominence, with the goal of expanding non‑surgical options.

• Single‑dose botulinum toxin treatments for glabellar and forehead lines
• Combination therapy using FTP‑002/FTP‑501
• Comparative efficacy of IPN10200 versus placebo
• Long‑term safety evaluation of NT 201

Results are intended to provide safe and effective alternatives for patients seeking facial rejuvenation.

Research explores the diffusion characteristics of botulinum toxin preparations and related skin responses, measuring factors such as anhidrotic halo size and sweating activity to understand underlying physical processes.

• Measurement of anhidrotic halo dimensions after toxin injection
• Analysis of protein‑complex effects on toxin spread
• Assessment of muscle contraction dynamics during treatment
• Quantification of standardized sweating activity in test areas

Insights from these studies guide formulation improvements and help predict clinical performance.