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Groupe Hospitalier Universitaire Paris Psychiatrie Et Neuroscience

Verified siteinfo

France 185 Rue Raymond Losserand, 75014 Paris, France

  • 85 trials recruiting
  • Non-small cell lung cancer · Non-small cell lung cancer metastatic · Ischaemic stroke
  • Adults and children

About Specializations

Groupe Hospitalier Universitaire Paris Psychiatrie Et Neuroscience in Paris, France specialises in clinical trials of conditions such as Non-small cell lung cancer, Non-small cell lung cancer metastatic, Ischaemic stroke, Non-small cell lung cancer stage IV, and other specialisations. This site conducts important research.

Main research areas of the site

Nervous System Diseases

The Institut de Neuromodulation is conducting studies that explore innovative therapies for acute ischemic stroke, aiming to improve functional recovery and quality of life.

  • Acute ischemic stroke
  • Aneurysmal subarachnoid hemorrhage
  • Traumatic brain injury
  • Intracerebral hemorrhage
  • Diffuse intrinsic pontine glioma

These efforts at Groupe Hospitalier Universitaire Paris Psychiatrie Et Neuroscience reflect a commitment to advancing neurocritical care.

Mental Disorders

Clinical research focuses on novel interventions for major depressive disorder and treatment‑resistant forms, seeking faster symptom relief.

  • Major Depressive Disorder
  • Treatment‑Resistant Depression
  • Generalized Anxiety Disorder
  • Ultra High Risk of Psychosis
  • Treatment‑Resistant Schizophrenia

The site’s multidisciplinary team integrates psychiatry and neuromodulation to enhance mental health outcomes.

Cardiovascular Diseases

Trials evaluate strategies to prevent secondary events after ischemic stroke and to optimize anticoagulation in patients with vascular pathology.

  • Ischemic stroke
  • Large vessel occlusion stroke
  • Aneurysmal subarachnoid hemorrhage
  • Anticoagulation after intracerebral hemorrhage
  • Endovascular coiling of unruptured aneurysms

Research at Groupe Hospitalier Universitaire Paris Psychiatrie Et Neuroscience aims to reduce mortality and disability from vascular disorders.

Immune System Diseases

Investigators are testing immunomodulatory approaches for myasthenia gravis and sickle cell disease, targeting disease progression and organ protection.

  • Myasthenia gravis
  • Sickle cell disease
  • Hospital‑acquired pneumonia
  • Sepsis in ICU
  • Immune‑mediated neuroinflammation in Alzheimer disease

The institute leverages its expertise in neuromodulation to modulate immune pathways for better patient outcomes.

Neoplasms

Oncologic studies address aggressive brain tumors such as diffuse intrinsic pontine glioma, testing targeted agents combined with radiotherapy.

  • Diffuse intrinsic pontine glioma
  • Other diffuse midline gliomas
  • Brain arteriovenous malformations
  • Glioma
  • High‑grade pediatric brain tumors

Through collaborations, the site strives to bring precision medicine to patients with rare central nervous system cancers.

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Site location
185 Rue Raymond Losserand75014 ParisFrance
Recruiting now
85 trials
Conditions studied
129
Partner status
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Ongoing trials

Clinical trials currently enrolling participants at this site.

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166 clinical trials

Obesity+2

Recruiting

Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease

Investigational
Countries:FranceFrance
  • Participants:18–64 years
  • Sponsor:Novo Nordisk A/S

Phase 3 study of ZL-1310 versus topotecan hydrochloride in patients with relapsed small cell lung cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Topotecan Hydrochloride
  • Sponsor:Zai Lab (US) LLC

Schizophrenia

Recruiting

Study of evenamide as add-on treatment for patients with treatment-resistant schizophrenia not adequately controlled by current antipsychotic medications

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Evenamide
  • Sponsor:Newron Pharmaceuticals S.p.A.

Study of laroprovstat (AZD0780) to reduce heart attack, stroke and vascular complications in patients with atherosclerotic cardiovascular disease or high risk of developing it

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Laroprovstat
  • Sponsor:AstraZeneca AB
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:AstraZeneca AB

A Study of Setidegrasib with Chemotherapy Drug Combination as First‑Line Treatment in Adults with KRAS G12D‑mutated Metastatic Pancreatic Cancer

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:ASP3082
  • Sponsor:Astellas Pharma Global Development Inc.

Adjuvant Datopotamab Deruxtecan with Drug Combination in Patients with High‑Risk Muscle‑Invasive Urothelial Carcinoma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Durvalumab
  • Sponsor:AstraZeneca AB

Neoplasm

Recruiting

Long‑term Safety of Adagrasib with Drug Combination in Adults with Solid Tumors

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Adagrasib
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

A Study of ABBV-706 to Assess Safety and Efficacy Compared with Standard Drug Combination in Adults with Relapsed or Refractory Small Cell Lung Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Topotecan
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Rinatabart Sesutecan plus bevacizumab vs standard care as maintenance for recurrent platinum‑sensitive ovarian cancer after second‑line chemotherapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Genmab A/S

Docetaxel and Apalutamide in Patients with Metastatic Hormone-Sensitive Prostate Cancer Who Did Not Have a Deep PSA Response After Initial Apalutamide Treatment

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Apalutamide

Pumitamig Versus Pembrolizumab in Patients With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company
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