TSC‑Related Epilepsy Research
At the Epilepsy Center Frankfurt Rhine-Main, investigators are focusing on Tuberous Sclerosis Complex–related seizures, exploring new options to improve long‑term control for both children and adults.
- Long‑term safety and tolerability evaluation
- Adjunctive therapy with Ganaxolone
- Inclusion of pediatric and adult populations
- Monitoring of seizure frequency and quality of life
The program underscores Goethe University Frankfurt’s commitment to advancing treatments for nervous system disorders.
Targeted Therapy for H3 K27M‑Mutant Diffuse Glioma
Researchers are evaluating a precision approach for patients with H3 K27M‑mutant diffuse glioma, aiming to enhance outcomes after standard radiotherapy.
- Molecularly driven drug assessment
- Post‑radiation maintenance strategy
- Exploration of survival benefit
- Integration of biomarker analysis
The study highlights the site’s expertise in neuro‑oncology within the broader neoplasm therapeutic area.
Vaccination Approach for Recurrent Glioblastoma and Astrocytoma
A novel immunotherapy trial is testing the CVGBM vaccine in patients who have undergone surgery for glioblastoma or astrocytoma, seeking to prevent tumor recurrence.
- Dose‑escalation safety assessment
- Evaluation of immune response activation
- Post‑surgical adjuvant treatment model
- Comprehensive adverse‑event monitoring
This effort reflects the center’s dedication to innovative cancer therapies within the neoplasms research portfolio.
