Geomedical Kft.

The department conducts studies aimed at improving outcomes for patients with heart failure, reducing risk in atherosclerotic cardiovascular disease, and managing hypertension. Research includes therapies that target lipoprotein(a) and strategies to prevent major adverse cardiovascular events.

• Heart failure with preserved or mildly reduced ejection fraction
• Atherosclerotic cardiovascular disease prevention
• Hypertension and cardiovascular risk management
• Lipoprotein(a) reduction therapies
• Major adverse cardiovascular events (MACE) prevention

Geomedical Kft. collaborates with leading cardiology units in Budapest to advance treatment options for these conditions.

Clinical investigations focus on inflammatory bowel conditions such as Crohn's disease and ulcerative colitis, evaluating both induction and maintenance approaches to achieve remission and improve quality of life.

• Induction therapy for moderate to severe Crohn's disease
• Maintenance strategies for ulcerative colitis
• Novel oral agents for inflammatory bowel disease
• Biologic alternatives for refractory IBD
• Patient‑reported outcome measures in IBD

The site’s gastroenterology team leverages its expertise to test new therapeutic options for these chronic gastrointestinal disorders.

Trials address immune‑mediated skin disorders, including atopic dermatitis, chronic spontaneous urticaria, and chronic pruritus of unknown origin, seeking effective and safe treatments for patients who have limited options.

• Targeted therapy for atopic dermatitis
• Management of chronic spontaneous urticaria
• Treatment of chronic pruritus of unknown origin
• Immune modulation in skin disease
• Safety of topical JAK inhibitors in youth

Geomedical Kft.’s immunology research integrates dermatology and systemic approaches to broaden therapeutic choices.

The site evaluates combination therapies for diabetic sensorimotor polyneuropathy, aiming to reduce neuropathic pain and improve functional outcomes for patients with diabetes‑related nerve damage.

• Combination therapy for diabetic neuropathy
• Pain reduction strategies in DSPN
• Functional outcomes in peripheral neuropathy
• Quality of life assessments in neuropathic patients
• Safety of multi‑modal treatment approaches

The neurologic research program collaborates with endocrinology specialists to address the complex needs of this population.

Studies explore integrated interventions for type 2 diabetes, obesity, and related metabolic risk factors, including the use of adjunctive agents with established glucose‑lowering medications.

• Adjunctive therapy with empagliflozin
• Weight management in heart failure patients
• Blood pressure control in diabetic populations
• Metabolic risk reduction strategies
• Integrated cardiovascular‑metabolic interventions

Geomedical Kft. leverages its metabolic clinic to test therapies that address both glycemic control and cardiovascular health.

Research includes trials for patients with moderate atopic dermatitis and severe itch, evaluating topical and systemic agents that aim to provide rapid symptom relief and long‑term disease control.

• Topical JAK inhibitor trials in adolescents
• Systemic therapy for severe eczema
• Itch reduction outcomes
• Safety of biologics in pediatric skin disease
• Long‑term efficacy of new dermal agents

The dermatology division at Geomedical Kft. focuses on translating novel mechanisms into practical treatments for patients.

Investigations into fundamental immune system phenomena support the development of cytokine‑targeted therapies and biomarker‑driven approaches across multiple disease categories.

• Cytokine blockade studies
• Biomarker identification in inflammatory disorders
• Immune response profiling
• Mechanistic studies of novel immunomodulators
• Translational immunology approaches

This foundational work underpins many of the site’s therapeutic programs and fosters collaborations with academic partners.