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Fraunhofer Institute for Translational Medicine and Pharmacology ITMP

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Germany Theodor-Stern-Kai 7, Sachsenhausen, 60596 Frankfurt, Germany

  • 1 trial recruiting
  • Psoriatic arthropathy · Systemic lupus erythematosus · Systemic scleroderma
  • Adults and children

About Specializations

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP in Frankfurt, Germany specialises in clinical trials of conditions such as Psoriatic arthropathy, Systemic lupus erythematosus, Systemic scleroderma, Autoimmune myositis, and other specialisations. This site conducts important research.

Main research areas of the site

Musculoskeletal Diseases

At Fraunhofer Institute for Translational Medicine and Pharmacology ITMP in Frankfurt, clinical research in musculoskeletal diseases focuses on inflammatory conditions such as rheumatoid arthritis and psoriatic arthritis. The trials are designed to test new treatment options and measure whether they can better reduce disease activity and improve symptoms.

  • Rheumatoid arthritis studies evaluating whether investigational therapies can improve joint inflammation and overall disease control
  • Psoriatic arthritis research assessing symptom relief and treatment effectiveness compared with placebo
  • Trials aimed at improving outcomes for people with chronic autoimmune joint disease

This area reflects a strong interest in immune-mediated inflammation and in finding better ways to manage long-term joint disease.

Skin and Connective Tissue Diseases

Research in skin and connective tissue diseases at this site includes studies in systemic sclerosis, a condition that can affect the skin and internal organs. The work is centered on evaluating whether new therapies can slow disease progression and improve organ-related outcomes.

  • Systemic sclerosis trials exploring effects on lung function and broader disease symptoms
  • Studies focused on treatment effectiveness for complex connective tissue disease
  • Research intended to support better control of disease-related complications

The Fraunhofer-Institut für Translationale Medizin und Pharmakologie contributes to efforts that connect laboratory insight with practical advances for patients living with rare and difficult-to-treat disorders.

Immune System Processes

The site also conducts trials in immune system processes, with a particular emphasis on autoimmune diseases such as systemic lupus erythematosus. These studies aim to assess whether new medicines can improve signs and symptoms while also supporting longer-term safety.

  • Systemic lupus erythematosus research evaluating symptom control and disease activity
  • Trials testing whether emerging therapies can offer better immune modulation
  • Long-term studies examining ongoing safety in adults with active autoimmune disease

Across these studies, the focus is on autoimmune inflammation and on advancing treatment options for patients with persistent immune-driven disease.

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Site location
Theodor-Stern-Kai 7, Sachsenhausen60596 FrankfurtGermany
Recruiting now
1 trial
Conditions studied
7
Partner status
Verified site

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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Type of trial
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Quick filters

12 clinical trials

Study on the Effect of Guselkumab for Treating Enthesitis in Patients with Psoriatic Arthritis Who Have Not Used Biologic DMARDs

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Guselkumab
  • Sponsor:Universitaetsklinikum Erlangen AöR

Psoriatic arthropathy

Not yet recruiting

A study to evaluate the long-term safety and effectiveness of sonelokimab in patients with psoriatic arthritis

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Sonelokimab
  • Sponsor:MoonLake Immunotherapeutics AG

Autoimmune myositis

Not yet recruiting

A study to evaluate the safety and effectiveness of CABA-201, fludarabine, and cyclophosphamide in patients with active inflammatory myopathy

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years
  • Substances:CABA-201
  • Sponsor:Cabaletta Bio Inc.

Immune-mediated myositis

Not yet recruiting

Study on the Effects of Rapcabtagene Autoleucel and Drug Combination for Patients with Severe Refractory Inflammatory Muscle Diseases

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Cyclophosphamide
  • Sponsor:Novartis Pharma AG

Systemic lupus erythematosus+1

Not yet recruiting

Study on the Effects of Rapcabtagene Autoleucel in Patients with Systemic Lupus Erythematosus and Active, Refractory Lupus Nephritis

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Azathioprine
  • Sponsor:Novartis Pharma AG

Systemic scleroderma

Not yet recruiting

Study comparing rapcabtagene autoleucel and rituximab in patients with severe refractory diffuse cutaneous systemic sclerosis

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Cyclophosphamide
  • Sponsor:Novartis Pharma AG

Psoriatic arthropathy

Not recruiting

Study of sonelokimab and risankizumab in adults with psoriatic arthritis who did not respond well to previous TNF inhibitor treatment

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Risankizumab
  • Sponsor:MoonLake Immunotherapeutics AG

Systemic scleroderma

Not recruiting

Study on BI 685509 for Adults with Systemic Sclerosis to Assess Effects on Lung Function and Symptoms

Investigational
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:BI 685509
  • Sponsor:Boehringer Ingelheim Espana S.A.

Psoriatic arthropathy

Not recruiting

Study on Izokibep for Improving Symptoms in Patients with Active Psoriatic Arthritis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Izokibep
  • Sponsor:Acelyrin Inc.

Rheumatoid arthritis

Not recruiting

Study of lutikizumab and ravagalimab in adults with moderate to severe rheumatoid arthritis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Lutikizumab
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Study on the Effectiveness and Safety of Cenerimod for Adults with Moderate to Severe Systemic Lupus Erythematosus

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Cenerimod
  • Sponsor:Viatris Innovation GmbH

Psoriatic arthropathy

Not recruiting

Study on the Effectiveness and Safety of Bimekizumab and Risankizumab in Adults with Active Psoriatic Arthritis

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bimekizumab
  • Sponsor:UCB Biopharma
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