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Flevoziekenhuis Stichting

Research site

The Netherlands Hospitaalweg 1, 1315 RA Almere, The Netherlands

  • 18 trials recruiting
  • Chronic lymphocytic leukaemia · Multiple sclerosis · B-cell small lymphocytic lymphoma
  • Adults and children

About Specializations

Flevoziekenhuis Stichting in Almere, The Netherlands specialises in clinical trials of conditions such as Chronic lymphocytic leukaemia, Multiple sclerosis, B-cell small lymphocytic lymphoma, Diffuse large B-cell lymphoma, and other specialisations. This site conducts important research.

Main research areas of the site

Oncology and Hematology

At Flevoziekenhuis Stichting, clinical trials in oncology and hematology focus on major cancers and blood cancers, including breast cancer, colon cancer, rectal cancer, esophageal adenocarcinoma, gastric cancer, non-small cell lung cancer, and several forms of lymphoma, multiple myeloma, and chronic lymphocytic leukemia. These studies are designed to test new treatment strategies, compare existing options, and improve survival and disease control.

  • Testing newer immunotherapy and targeted treatment combinations
  • Evaluating treatment effectiveness in advanced or relapsed cancers
  • Studying ways to improve outcomes after surgery or standard therapy

Research in this area also includes approaches aimed at better managing advanced cancer and reducing recurrence after treatment.

Women’s Health, Reproductive Medicine, and Obstetrics

The site’s Obstetrics & Gynecology department supports studies in female urogenital diseases, pregnancy complications, and reproductive health. Key topics include placenta previa, preterm birth, polycystic ovary syndrome, uterine fibroids, vulvar high-grade squamous intraepithelial lesion, and contraception. These trials aim to improve prevention, symptom control, and long-term women’s health.

  • Assessing ways to prevent preterm birth and pregnancy-related complications
  • Evaluating treatments for uterine fibroids and vulvar precancerous disease
  • Studying contraceptive options and fertility-related care

Several studies also look at improving quality of life for women living with chronic gynecologic conditions.

Respiratory, Infectious, and Critical Care Research

Clinical research at this hospital includes respiratory tract diseases, bacterial infections, and virus diseases, with studies in pneumonia, influenza, respiratory tract infection, and Staphylococcus aureus bacteremia. The main goal is to improve outcomes for hospitalized patients by testing better treatment strategies and reducing complications from serious infections.

  • Evaluating therapies for hospitalized patients with acute respiratory infections
  • Studying ways to lower infection-related complications and cardiovascular risk
  • Comparing treatment durations and supportive care approaches for bacterial infection

This area reflects a strong interest in practical, patient-centered care for common but potentially severe infections.

Cardiovascular and Kidney Disease

Trials in cardiovascular diseases and kidney-related care include patients with myocardial infarction, ischemic stroke, transient ischemic attack, and advanced chronic kidney disease. Researchers are exploring whether existing treatments can better prevent major heart, brain, and kidney complications while also supporting day-to-day well-being.

  • Testing strategies to reduce major cardiovascular events
  • Studying therapies for patients with severe kidney impairment
  • Evaluating quality of life alongside clinical outcomes

The work in this field combines prevention, long-term risk reduction, and improved care for older or medically complex patients.

Neurology, Ophthalmology, and Endocrine Disorders

Research in nervous system diseases, eye diseases, and hormonal disorders includes multiple sclerosis, myopia, and hypothyroidism. These studies are focused on making treatment more personalized, easing persistent symptoms, and maintaining disease control over time.

  • Personalizing treatment for multiple sclerosis
  • Comparing approaches to slow progression of myopia
  • Exploring better relief for ongoing symptoms in hypothyroidism

The research aims to improve both effectiveness and tolerability in chronic conditions that can affect quality of life.

Digestive System and Surgical Research

Studies in digestive system diseases and procedure-related care address perianal abscess, rectal cancer, and stomach cancer with peritoneal spread. The purpose is to improve surgical outcomes, reduce complications, and refine treatment choices for patients needing complex gastrointestinal care.

  • Testing whether added medical treatment can reduce complications after drainage of perianal abscess
  • Evaluating organ-preserving approaches in early rectal cancer
  • Comparing treatment strategies for advanced gastric cancer

These trials support more effective and less invasive care across several gastrointestinal conditions.

Skin, Allergy, and Public Health Research

The site also conducts studies in skin and connective tissue diseases and environment and public health, including atopic eczema and broader efforts to improve treatment use in real-world care. These trials often focus on balancing symptom control, safety, and long-term practicality for patients.

  • Assessing treatment approaches for atopic eczema
  • Looking at safer or more convenient long-term care strategies
  • Supporting better treatment planning in routine clinical practice

Research in this area helps bridge the gap between controlled treatment settings and everyday patient care.

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Site location
Hospitaalweg 11315 RA AlmereThe Netherlands
Recruiting now
18 trials
Conditions studied
43

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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43 clinical trials

Effect of elecoglipron plus dapagliflozin on cardiovascular outcomes in adults with heart failure with preserved or mildly reduced ejection fraction (HFpEF/HFmrEF)

Registered drug
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

A study comparing BGB-11417 and zanubrutinib with venetoclax and acalabrutinib for patients with previously untreated chronic lymphocytic leukemia

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Acalabrutinib
  • Sponsor:BeOne Medicines I GmbH

Study of pembrolizumab, capecitabine, or olaparib in patients with early-stage triple negative breast cancer and remaining disease after initial treatment

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

Study of sonrotoclax plus obinutuzumab or rituximab compared to venetoclax plus rituximab in patients with relapsed or refractory chronic lymphocytic leukemia

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Obinutuzumab
  • Sponsor:BeOne Medicines AG

Study on Letrozole and Gonadotropins for Women with Polycystic Ovary Syndrome (PCOS) to Improve Live Birth Rates

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years
  • Substances:Follitropin Alfa
  • Sponsor:Amsterdam UMC Stichting

Rectal cancer

Recruiting

Study Comparing Surgery and Chemoradiotherapy with Capecitabine for Early Rectal Cancer Patients

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Amsterdam UMC Stichting

Study on Statins for Frail Older Patients with Recent Ischemic Stroke or TIA: Fluvastatin, Simvastatin, Pravastatin Sodium, Atorvastatin, and Rosuvastatin Combination

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:65+ years
  • Substances:Atorvastatin
  • Sponsor:Amsterdam UMC Stichting

Hypothyroidism

Recruiting

Study on Levothyroxine and Liothyronine for Patients with Autoimmune Hypothyroidism and Persistent Tiredness

Registered drug
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

Study Comparing Ulipristal Acetate and Surgery for Women with Symptomatic Uterine Fibroids

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years
  • Substances:Ulipristal Acetate
  • Sponsor:Amsterdam UMC Stichting

Study on Stopping or Continuing Clopidogrel, Carbasalate Calcium, and Dipyridamole for Young Patients After Stroke Without a Known Cause

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years
  • Substances:Acetylsalicylic Acid
  • Sponsor:Radboud universitair medisch centrum Stichting

Study on Adding Trastuzumab and Pertuzumab to Treatment for Patients with Resectable HER2 Positive Esophageal Cancer

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Pertuzumab
  • Sponsor:Amsterdam UMC Stichting

Colon cancer

Recruiting

Study on Pre-Surgery Immunotherapy with Relatlimab, Anti-IL-8 mAb, and Ipilimumab for Early-Stage Colon Cancer Patients

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Celecoxib
  • Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
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