Rare diseases
Investigational molecules
Locations
V Uvalu 84/1, Motol, 150 00 Prague, Czechia
Fakultni nemocnice Motol a Homolka in Prague, Czechia specialises in clinical trials of conditions such as Hidradenitis, Non-small cell lung cancer, Bladder transitional cell carcinoma, Breast cancer, and other specialisations. This site conducts important research.
Clinical research at Fakultni nemocnice Motol a Homolka focuses on inflammatory conditions that affect joints, skin, and connective tissues, with a strong emphasis on psoriatic arthritis. The trials are designed to assess whether new treatment options can better control disease activity and improve patient outcomes.
This research reflects a collaborative clinical environment in Praha, where specialists in rheumatology are working to expand treatment choices for people with active inflammatory disease.
The site is conducting studies centered on psoriatic arthritis, a condition that links musculoskeletal inflammation with skin and connective tissue involvement. The main goal is to determine how well emerging therapies can reduce disease signs and support better long-term management.
With experienced investigators at Oddělení revmatologie dětí a dospělých, the research program brings together both adult and pediatric rheumatology expertise.
These trials explore treatment strategies for diseases within the musculoskeletal and connective tissue fields, aiming to improve symptom control and overall response in people living with chronic inflammatory arthritis.
The research activity at this health care institution in Czechia highlights a strong clinical focus on practical treatment improvement rather than basic laboratory work.
Clinical trials at the site are concentrated in rheumatology, especially conditions where inflammation affects both joints and skin. The studies aim to clarify which therapies may offer better relief for patients with active psoriatic arthritis.
With a substantial investigator base, Fakultni nemocnice Motol a Homolka supports ongoing clinical evaluation of new approaches in a specialized rheumatology setting.
Clinical trials currently enrolling participants at this site.
Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease
CzechiaLong‑Term Safety and Efficacy of SPY001-001, SPY002 and SPY003 in Adults with Ulcerative Colitis
CzechiaLong-term Safety and Efficacy of Remibrutinib in Adults with Moderate to Severe Hidradenitis Suppurativa
CzechiaA study of loxo-435, enfortumab vedotin, and pembrolizumab in adults with advanced or metastatic bladder cancer
CzechiaStudy of sotorasib, panitumumab and a drug combination for patients with metastatic colorectal cancer with KRAS p.G12C mutation.
CzechiaStudy of BNT327 and a drug combination for patients with untreated metastatic or locally recurrent triple-negative breast cancer
CzechiaA Study of Long-acting Antibodies SPY001-001 and SPY002 Alone and Combined for Adults with Moderate to Severe Ulcerative Colitis
CzechiaA study of navenibart for long-term safety in patients with hereditary angioedema
CzechiaA Study of Visugromab Compared to Placebo in Patients with Cancer-Related Cachexia to Test How Well It Works and How Safe It Is
CzechiaA Study of Ivonescimab Combined with Fluorouracil, Folinic Acid, and Oxaliplatin Compared to Bevacizumab for Patients with Metastatic Colorectal Cancer
CzechiaStudy of NGM120 in patients with colorectal cancer and cancer cachexia: Evaluating effects on body weight
CzechiaStudy of nadofaragene firadenovec alone or with gemcitabine, docetaxel or pembrolizumab in adults with non-muscle invasive bladder cancer who did not respond to BCG therapy
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