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Clinique Victor Hugo

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France Centre De Cancerologie De La Sarthe, 64 Rue De Degre, 72000 Le Mans, France

  • 28 trials recruiting
  • Squamous cell carcinoma of head and neck · Prostate cancer · Breast cancer
  • Adults and children

About Specializations

Clinique Victor Hugo in Le Mans, France specialises in clinical trials of conditions such as Squamous cell carcinoma of head and neck, Prostate cancer, Breast cancer, Hormone receptor positive HER2 negative breast cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Head and Neck Cancer

The medical center is at the forefront of research in head and neck cancer, focusing on innovative treatment combinations to enhance patient outcomes. The ongoing study investigates the efficacy of combining radiotherapy with cetuximab and xevinapant, a promising study drug, compared to the traditional combination with a placebo.

  • Radiotherapy and Cetuximab Combination
  • Xevinapant as a Study Drug
  • Locally Advanced Squamous Cell Carcinoma

This research aims to demonstrate significant improvements in progression-free survival (PFS), evaluated by an independent review committee, offering new hope for patients with locally advanced squamous cell carcinoma of the head and neck.

Prostate Cancer

Specializing in prostate cancer, the center is conducting pivotal research on treatment strategies for metastatic hormone-sensitive prostate cancer. The study explores the potential benefits of adding abemaciclib to the standard regimen of abiraterone and prednisone.

  • Abemaciclib and Abiraterone Combination
  • Hormonal Treatment Response
  • High-Risk Metastatic Cases

The primary objective is to assess improvements in radiographic progression-free survival (rPFS), providing critical insights into more effective treatment protocols for high-risk patients.

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Site location
Centre De Cancerologie De La Sarthe, 64 Rue De Degre72000 Le MansFrance
Recruiting now
28 trials
Conditions studied
49
Partner status
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Ongoing trials

Clinical trials currently enrolling participants at this site.

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87 clinical trials

Docetaxel and Apalutamide in Patients with Metastatic Hormone-Sensitive Prostate Cancer Who Did Not Have a Deep PSA Response After Initial Apalutamide Treatment

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Apalutamide

Belzutifan and Zanzalintinib in Adults with Advanced Renal Cell Carcinoma After PD-1/L1 and VEGF-TKI Therapy

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Belzutifan
  • Sponsor:Merck Sharp & Dohme LLC

Evaluating the use of capecitabine, oxaliplatin, fluorouracil, folinic acid, and irinotecan to personalize chemotherapy for patients with stage III colorectal cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Unicancer

A study of ficerafusp alfa and nivolumab in patients with head and neck cancer who did not respond to platinum-based chemotherapy.

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Nivolumab
  • Sponsor:Groupe Oncologie Radiotherapie Tete Cou

Study of Revumenib and Chemotherapy for Patients with Newly Diagnosed Acute Myeloid Leukemia with NPM1 Gene Mutation

Registered drug
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Cytarabine
  • Sponsor:Syndax Pharmaceuticals Inc.

Study of ivonescimab alone or with ligufalimab versus pembrolizumab for patients with recurrent or metastatic head and neck squamous cell cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Ivonescimab
  • Sponsor:Groupe Oncologie Radiotherapie Tete Cou

A Study of Amivantamab With Carboplatin and Pembrolizumab for Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Amivantamab
  • Sponsor:Janssen Cilag International

Study of ribociclib with or without chemotherapy for patients with hormone receptor positive, HER2 negative early breast cancer at intermediate risk

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:Unicancer

Breast cancer

Recruiting

A Study of BNT323 and BNT327 for Patients with Advanced Breast Cancer to Test Safety and Effectiveness

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:BNT327
  • Sponsor:BioNTech SE

Prostate cancer

Recruiting

A study of saruparib with radiotherapy and hormone therapy for men with high-risk prostate cancer who have a BRCA gene mutation

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone Acetate
  • Sponsor:AstraZeneca AB

Prostate cancer

Recruiting

Study of xaluritamig plus abiraterone for men with metastatic castration-resistant prostate cancer who have not received chemotherapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone Acetate
  • Sponsor:Amgen Inc.

Endometrial cancer+1

Recruiting

A study comparing BNT323 with chemotherapy in patients with HER2-expressing recurrent endometrial cancer who received previous treatment

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:DB-1303
  • Sponsor:BioNTech SE
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