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Charite Research Organisation GmbH

Verified siteinfo

Germany Chariteplatz 1, Mitte, 10117 Berlin, Germany

  • 30 trials recruiting
  • Malignant melanoma · Colitis ulcerative · Dermatitis atopic
  • Adults and children

About Specializations

Charite Research Organisation GmbH in Berlin, Germany specialises in clinical trials of conditions such as Malignant melanoma, Colitis ulcerative, Dermatitis atopic, Hidradenitis, and other specialisations. This site conducts important research.

Main research areas of the site

Oncology

Charité Research Organisation advances cancer care by testing innovative therapies for a wide range of solid tumors and hematologic malignancies.

  • Advanced melanoma
  • Non‑small cell lung cancer
  • Colorectal cancer
  • Breast cancer (HER2‑positive and HER2‑low)
  • High‑grade serous ovarian cancer
  • Renal cell carcinoma
  • Lymphoma (diffuse large B‑cell, Hodgkin’s, peripheral T‑cell)

The trials aim to evaluate efficacy and safety of targeted agents and immunotherapies, helping to improve treatment outcomes for patients across Berlin and beyond.

Immunology & Autoimmune Disorders

Research at Charité focuses on immune‑mediated diseases, exploring new biologics that modulate the immune response.

  • Atopic dermatitis
  • Plaque psoriasis
  • Ulcerative colitis
  • Crohn’s disease
  • Systemic lupus erythematosus
  • Chronic inflammatory demyelinating polyneuropathy

These studies assess whether novel agents can reduce disease activity and improve quality of life for individuals living with chronic inflammation.

Metabolic & Endocrine Disorders

The site conducts trials targeting metabolic health, including obesity and diabetes management.

  • Type 2 Diabetes Mellitus
  • Obesity
  • Metabolic syndrome
  • Nutritional deficiencies

Objectives include testing agents that promote weight loss, improve glycemic control, and address associated cardiovascular risk factors.

Cardiovascular and Respiratory Diseases

Charité’s program evaluates therapies for cardiopulmonary conditions, aiming to alleviate symptoms and slow disease progression.

  • Chronic obstructive pulmonary disease (COPD)
  • Mild to moderate asthma
  • Hypertension
  • Heart failure

The research measures functional improvement, reduction in exacerbations, and overall patient well‑being.

Infectious Diseases

Studies at Charité address serious bacterial infections and sepsis, testing new antimicrobial strategies.

  • Clostridioides difficile infection
  • Sepsis
  • Septic shock

Trials focus on safety and efficacy of novel antibiotics or adjunctive therapies to improve survival and recovery rates.

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Site location
Chariteplatz 1, Mitte10117 BerlinGermany
Recruiting now
30 trials
Conditions studied
80
Partner status
Verified site

More sites in BerlinGermany

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

94 clinical trials

Study on the Effectiveness and Safety of Deucravacitinib for Adults with Active Sjogren's Syndrome

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Deucravacitinib
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Breast cancer+1

Recruiting

Evaluation of zongertinib, fulvestrant and goserelin acetate in patients with HR‑positive HER2‑negative advanced breast cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Fulvestrant
  • Sponsor:Medica Scientia Innovation Research S.L.

Safety and Efficacy of BMS-986528 with Tocilizumab in Patients with Refractory Rheumatoid Arthritis: A Phase 1/2a Open‑Label Study

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:Tocilizumab
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Efficacy and safety of votoplam in adults with Huntington’s disease: a randomized, double‑blind, placebo‑controlled Phase 3 trial

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Votoplam
  • Sponsor:Novartis Pharma AG

Bladder cancer

Recruiting

Study of Enfortumab Vedotin and Pembrolizumab for Bladder Preservation in Patients with Muscle‑Invasive Bladder Cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Enfortumab Vedotin
  • Sponsor:Astellas Pharma Global Development Inc.

A study of LY4268989 and mirikizumab in adults with moderately to severely active ulcerative colitis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Mirikizumab
  • Sponsor:Eli Lilly & Co.

A Study of Felzartamab for Kidney Transplant Patients with Late Isolated Microvascular Inflammation

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Felzartamab
  • Sponsor:Biogen Idec Research Limited

Vusolimogene Oderparepvec with Nivolumab for Advanced Melanoma Patients Whose Cancer Progressed After Previous Immunotherapy Treatments

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Dacarbazine Citrate
  • Sponsor:Replimune Group Inc.

Study on the Effects of Mexiletine for Treating Myotonic Dystrophy Types 1 and 2 in Patients

Investigational
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Mexiletine Hydrochloride
  • Sponsor:Lupin Atlantis Holdings SA

Study on the Effectiveness and Safety of Myrrh, Coffee Charcoal, and Chamomile Extract for Patients with Diarrhea-Dominant or Mixed-Type Irritable Bowel Syndrome

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Coffee Charcoal
  • Sponsor:REPHA GmbH Biologische Arzneimittel

Long-Term Safety and Efficacy Study of Mexiletine Hydrochloride for Patients with Myotonic Dystrophy Type 1 and Type 2

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Mexiletine Hydrochloride
  • Sponsor:Lupin Atlantis Holdings SA

Hereditary ataxia+1

Recruiting

Study on the Safety of VO659 for Patients with Spinocerebellar Ataxia Types 1, 3, and Huntington's Disease

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:VO659
  • Sponsor:Vico Therapeutics B.V.
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