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Centru De Evaluare Si Tratament A Toxicodependentelor Pentru Tineri Sf. Stelian

Research site

Romania Strada Ing Cristian Pascal 25-27 Sector 6, 060222 Bucharest, Romania

  • 7 trials recruiting
  • Major depression · Schizophrenia · Bipolar I disorder
  • Adult patients

About Specializations

Centru De Evaluare Si Tratament A Toxicodependentelor Pentru Tineri Sf. Stelian in Bucharest, Romania specialises in clinical trials of conditions such as Major depression, Schizophrenia, Bipolar I disorder, Dementia Alzheimer's type, and other specialisations. This site conducts important research.

Main research areas of the site

Behavioral Disciplines and Activities

The Centru De Evaluare Si Tratament A Toxicodependentelor Pentru Tineri Sf. Stelian conducts research that examines how targeted behavioral strategies can improve outcomes for patients with serious psychiatric conditions such as schizophrenia, bipolar I disorder, and major depressive disorder.

  • Adjunctive treatments for schizophrenia
  • Management of mania and mixed features in bipolar disorder
  • Strategies to reduce agitation in Alzheimer’s dementia
  • Relapse prevention for depression with anhedonia
  • Long‑term safety assessments of novel psychotropic agents

With 13 active studies and a team of seven investigators, the site offers a comprehensive platform for evaluating new therapies and behavioral interventions in a real‑world clinical setting.

Mental Disorders

Research at this Bucharest hospital focuses on the core mental disorders that affect young adults, including schizophrenia, bipolar I disorder, and major depressive disorder. The goal is to test innovative drugs and combination regimens that may provide faster relief and better long‑term stability.

  • Efficacy of new antipsychotics for treatment‑resistant schizophrenia
  • Acute and maintenance therapy for bipolar mania
  • Adjunctive antidepressant strategies for moderate‑to‑severe anhedonia
  • Treatment of psychosis associated with Alzheimer’s disease
  • Safety monitoring of long‑term adjunctive therapies

The program integrates clinical expertise with rigorous trial design, aiming to expand therapeutic options for patients struggling with severe mental illness.

Psychological Phenomena

Studies under the Psychological Phenomena umbrella explore specific symptom clusters such as anhedonia and agitation, seeking to understand how these experiences impact overall disease burden and treatment response.

  • Assessing relapse risk linked to anhedonia in depression
  • Measuring agitation levels in Alzheimer’s dementia
  • Evaluating behavioral and psychological symptoms of schizophrenia
  • Investigating mood stabilization in bipolar patients with mixed features
  • Long‑term tolerability of novel agents addressing psychological symptoms

By linking symptom‑focused outcomes with broader clinical endpoints, the site contributes valuable insights that may guide personalized treatment strategies.

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Site location
Strada Ing Cristian Pascal 25-27 Sector 6060222 BucharestRomania
Recruiting now
7 trials
Conditions studied
9

More sites in BucharestRomania

Recruiting now

Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
Quick filters

14 clinical trials

Schizophrenia

Recruiting

A Study Testing Brexpiprazole Given Once Weekly to Treat Sudden Worsening of Symptoms in Patients with Schizophrenia

Registered drug
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Brexpiprazole
  • Sponsor:Otsuka Pharmaceutical Co. Ltd.

Bipolar I disorder+1

Recruiting

Long-term safety study of trospium chloride and xanomeline tartrate combination (KarXT) for treatment of manic episodes in adults with Bipolar I Disorder

InvestigationalNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Trospium Chloride
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Bipolar I disorder+1

Recruiting

Study of trospium chloride and xanomeline tartrate (KarXT) for treating manic episodes in adults with bipolar I disorder

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years
  • Substances:Trospium Chloride
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Safety and Tolerability Study of NBI-1065845 as Additional Treatment for Adults with Major Depressive Disorder

InvestigationalNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:9-(4-CYCLOHEXYLOXYPHENYL)-7-METHYL-3,4-DIHYDROPYRAZINO[2,1-C][1,2,4]THIADIAZINE 2,2-DIOXIDE
  • Sponsor:Neurocrine Biosciences Inc.

Assessment of NBI-1065845 as an Additional Treatment for Adults with Major Depressive Disorder

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:9-(4-CYCLOHEXYLOXYPHENYL)-7-METHYL-3,4-DIHYDROPYRAZINO[2,1-C][1,2,4]THIADIAZINE 2,2-DIOXIDE
  • Sponsor:Neurocrine Biosciences Inc.

Study on ITI-1284 for Treating Agitation in Alzheimer's Patients

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:ITI-1284
  • Sponsor:Intra-Cellular Therapies Inc.

Psychotic disorder+2

Recruiting

Study on ITI-1284 for Treating Psychosis in Alzheimer's Patients

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:ITI-1284
  • Sponsor:Intra-Cellular Therapies Inc.

Major depression

Not yet recruiting

Long‑Term Safety, Tolerability and Efficacy of Azetukalner in Patients with Major Depressive Disorder

InvestigationalNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Major depression

Not yet recruiting

A study of azetukalner compared to placebo for adults with moderate-to-severe major depressive disorder

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Bipolar disorder

Not recruiting

Study on Lumateperone for Treating Manic Episodes in Bipolar I Disorder Patients

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Lumateperone
  • Sponsor:Intra-Cellular Therapies Inc.

Major depression+1

Not recruiting

Study on Aticaprant and Antidepressant for Preventing Relapse in Adults with Major Depressive Disorder and Anhedonia

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years
  • Substances:Aticaprant
  • Sponsor:Janssen Cilag International

Schizophrenia

Not recruiting

Study on Valbenazine for Patients with Schizophrenia Not Responding Well to Antipsychotic Treatment

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Valbenazine Ditosylate
  • Sponsor:Neurocrine Biosciences Inc.
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