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Centro Hospitalar De Lisboa Ocidental E.P.E.

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Portugal Estrada Forte Do Alto Duque, 1449-005 Lisbon, Portugal

  • 28 trials recruiting
  • Sjogren's syndrome · Chronic inflammatory demyelinating polyradiculoneuropathy · Crohn's disease
  • Adults and children

About Specializations

Centro Hospitalar De Lisboa Ocidental E.P.E. in Lisbon, Portugal specialises in clinical trials of conditions such as Sjogren's syndrome, Chronic inflammatory demyelinating polyradiculoneuropathy, Crohn's disease, Dementia Alzheimer's type, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases

The department is conducting research focused on cardiovascular diseases, addressing conditions such as heart failure with preserved ejection fraction and atrial fibrillation. Trials aim to assess new anticoagulant strategies and anti‑inflammatory therapies to reduce stroke risk and improve heart failure outcomes.

  • Heart failure with preserved ejection fraction and systemic inflammation
  • Anticoagulation therapy for atrial fibrillation to prevent stroke
  • Inflammation‑targeted treatment to lower cardiovascular mortality

At Centro Hospitalar De Lisboa Ocidental, five investigators are leading these studies, contributing to advances in cardiovascular care in Lisbon.

Eye Diseases

The ophthalmology department is engaged in studies on eye diseases, specifically retinopathy of prematurity. The trial evaluates long‑term safety and visual function of a novel treatment for this condition.

  • Retinopathy of prematurity long‑term outcomes
  • Visual function assessment in premature infants
  • Safety monitoring of new ocular therapy

These investigations are carried out at Centro Hospitalar De Lisboa Ocidental, with a team of five clinicians aiming to improve pediatric eye health across Portugal.

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Site location
Estrada Forte Do Alto Duque1449-005 LisbonPortugal
Recruiting now
28 trials
Conditions studied
66
Partner status
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Ongoing trials

Clinical trials currently enrolling participants at this site.

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76 clinical trials

Study on Seltorexant for Adults and Elderly with Major Depressive Disorder and Insomnia Symptoms

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Seltorexant
  • Sponsor:Janssen Cilag International

Study on the Safety of BHV-7000 for Adults with Hard-to-Treat Focal Onset Epilepsy

InvestigationalNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:BHV-7000
  • Sponsor:Biohaven Therapeutics Ltd.

Study on Long-Term Safety of Ianalumab for Patients with Systemic Lupus Erythematosus

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Emtricitabine
  • Sponsor:Novartis Pharma AG

Zenagamtide versus semaglutide: a study of blood sugar and weight reduction in adults with type 2 diabetes inadequately controlled on metformin and/or SGLT2 inhibitor

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Semaglutide
  • Sponsor:Novo Nordisk A/S

A study to evaluate the effectiveness and safety of remibrutinib in patients with secondary progressive multiple sclerosis

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Remibrutinib
  • Sponsor:Novartis Pharma AG

A study of RO7268489 added to ocrelizumab compared to placebo in adults with progressive multiple sclerosis

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years
  • Substances:Ocrelizumab
  • Sponsor:F. Hoffmann-La Roche AG

Study of sacituzumab tirumotecan, pembrolizumab and chemotherapy combination for early-stage triple-negative breast cancer or hormone receptor-low positive/HER2-negative breast cancer

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Merck Sharp & Dohme LLC

Study of mRNA-4157 and Pembrolizumab for Patients with Metastatic Melanoma

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:MRNA-4157
  • Sponsor:Merck Sharp & Dohme LLC

Study on the Effects of Faricimab for Caucasian Patients with Polypoidal Choroidal Vasculopathy

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Faricimab
  • Sponsor:Association For Innovation And Biomedical Research On Light And Image

Study on Long-term Safety and Efficacy of Riliprubart for Patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

InvestigationalNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Riliprubart
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Study on the Effectiveness and Safety of Efgartigimod PH20 SC for Adults with Systemic Sclerosis

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Efgartigimod Alfa
  • Sponsor:Argenx

Psychotic disorder+1

Recruiting

Study of trospium chloride and xanomeline tartrate (KarXT) in patients with psychosis associated with Alzheimer's disease

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Trospium Chloride
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company
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