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Centre Hospitalier Saint Nazaire

Research site

France 11 Boulevard Georges Charpak, Bp 414, 44606 St Nazaire, France

  • 12 trials recruiting
  • Squamous cell carcinoma of head and neck · Immune thrombocytopenia · Ischaemic stroke
  • Adults and children

About Specializations

Centre Hospitalier Saint Nazaire in St Nazaire, France specialises in clinical trials of conditions such as Squamous cell carcinoma of head and neck, Immune thrombocytopenia, Ischaemic stroke, Pneumonia, and other specialisations. This site conducts important research.

Main research areas of the site

Oncology and Hematologic Malignancies

At Centre Hospitalier Saint Nazaire, the medical oncology program includes studies in neoplasms, with a strong focus on breast cancer, head and neck squamous cell carcinoma, multiple myeloma, and follicular lymphoma. These trials are mainly designed to evaluate new treatment approaches, compare combination strategies, and improve disease control and survival.

  • Testing new treatment combinations for recurrent, metastatic, and locally advanced head and neck cancers
  • Evaluating maintenance and relapse strategies in multiple myeloma
  • Studying targeted and immune-based options for follicular lymphoma
  • Assessing personalized therapy choices in early and high-risk breast cancer

Overall, this research area centers on improving effectiveness, extending survival, and refining treatment selection for patients with complex cancers.

Blood Disorders and Immune Conditions

Clinical research also covers hemic and lymphatic diseases and immune system diseases, including immune thrombocytopenia, myelodysplastic syndromes, and related inflammatory or bleeding disorders. The purpose of these trials is to compare supportive and disease-directed treatments, while seeking safer and more effective ways to manage symptoms and long-term outcomes.

  • Improving treatment options for adults with persistent or chronic immune thrombocytopenia
  • Studying better timing of therapy in low-risk myelodysplastic syndrome
  • Exploring new immune-modulating strategies for blood-related disorders
  • Evaluating treatment effectiveness and response durability in hematology care

This portfolio reflects a broad interest in balancing efficacy, safety, and quality of life for patients with chronic hematologic conditions.

Cardiovascular and Cerebrovascular Research

Trials in cardiovascular diseases and nervous system diseases include conditions such as stroke, intracerebral hemorrhage, transient ischemic attack, myocardial infarction, and atherosclerosis. These studies aim to improve prevention and treatment strategies, reduce complications, and support better recovery after major vascular events.

  • Assessing approaches to reduce risk after intracerebral hemorrhage
  • Evaluating long-term prevention of recurrent vascular events
  • Studying treatments for stroke and other ischemic brain injuries
  • Improving care for patients with coronary syndrome and related heart disease

These projects focus on practical ways to lower recurrence, improve outcomes, and support recovery in patients with serious cardiovascular and neurological disease.

Infectious and Respiratory Disease Studies

The site contributes to research in bacterial infections and mycoses as well as respiratory tract diseases, with studies involving community-acquired pneumonia and bartonellosis. The main goal is to compare treatment choices and determine whether simpler or more targeted therapy can provide similar clinical benefit.

  • Comparing antibiotic strategies for older adults with community-acquired pneumonia
  • Investigating treatment options for bartonellosis and related lymph node infection
  • Supporting better antimicrobial use in routine hospital care
  • Exploring effectiveness while limiting unnecessary treatment exposure

These studies reflect a focus on improving everyday infectious disease care through more precise and effective treatment decisions.

Surgical, Supportive, and Symptom-Relief Research

Another area of activity involves anesthesia and analgesia, along with supportive care for conditions such as hemorrhoidal disease and postoperative discomfort. Trials in this field are designed to improve comfort, pain control, and recovery in the hospital setting.

  • Evaluating methods to reduce postoperative pain and discomfort
  • Studying symptom relief during critical care recovery
  • Improving patient comfort after procedures for hemorrhoids
  • Testing supportive approaches that may enhance recovery experience

At Centre Hospitalier Saint Nazaire, these studies emphasize patient-centered care by focusing on comfort, recovery quality, and practical symptom management.

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Site location
11 Boulevard Georges Charpak, Bp 41444606 St NazaireFrance
Recruiting now
12 trials
Conditions studied
19

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Clinical trials currently enrolling participants at this site.

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24 clinical trials

Study of personalized treatment using drug combination therapy for young women with early stage hormone receptor-positive breast cancer based on gene expression testing

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Anastrozole
  • Sponsor:Unicancer

A study of ficerafusp alfa and nivolumab in patients with head and neck cancer who did not respond to platinum-based chemotherapy.

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Ficerafusp alfa
  • Sponsor:Groupe Oncologie Radiotherapie Tete Cou

A study comparing odronextamab combined with chemotherapy versus rituximab combined with chemotherapy in adults with previously untreated follicular lymphoma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Cyclophosphamide
  • Sponsor:Regeneron Pharmaceuticals Inc.

Study of ivonescimab alone or with ligufalimab versus pembrolizumab for patients with recurrent or metastatic head and neck squamous cell cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Ivonescimab
  • Sponsor:Groupe Oncologie Radiotherapie Tete Cou

Study on the Effect of Continuous Intravenous Lidocaine and Sodium Chloride on Comfort in Postoperative Critical Care Patients

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:Centre Hospitalier Universitaire De Rennes

Study Comparing Elranatamab and Lenalidomide with Daratumumab and Lenalidomide for Maintenance Therapy in Newly Diagnosed Multiple Myeloma Patients

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Daratumumab
  • Sponsor:Centre Hospitalier Universitaire De Nantes

Study Comparing Continuous and Fixed Duration Therapy with Daratumumab, Lenalidomide, and Dexamethasone for Patients with Relapsed Multiple Myeloma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Daratumumab
  • Sponsor:Assistance Publique Hopitaux De Paris

Study on Colchicine and Ticagrelor for Preventing Ischemic Stroke in Patients with Atherosclerosis

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Colchicine
  • Sponsor:Assistance Publique Hopitaux De Paris

Study of avelumab and cetuximab combination treatment after TPEx chemotherapy for patients with recurrent or metastatic head and neck cancer receiving first-line therapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Avelumab
  • Sponsor:Groupe Oncologie Radiotherapie Tete Cou

Pneumonia

Recruiting

Study Comparing Amoxicillin and Amoxicillin/Clavulanic Acid for Treating Community-Acquired Pneumonia in Patients Aged 65 and Older

Registered drugNo placebo
Countries:FranceFrance
  • Participants:65+ years
  • Substances:Amoxicillin
  • Sponsor:Centre Hospitalier Universitaire De Nantes

Study Comparing Capsaicin Patch and Duloxetine for Patients with Chemotherapy-Induced Peripheral Neuropathy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Capsaicin
  • Sponsor:Institut De Cancerologie De L Ouest

Study on Avoiding Anticoagulation with Apixaban for Patients with Intracerebral Hemorrhage

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Apixaban
  • Sponsor:Centre Hospitalier Universitaire De Lille
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