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Centre Hospitalier Lyon Sud

Verified siteinfo

France 165 Chemin du Grand Revoyet, Pavillon Médical Bat 1A, Rhône, 69494 Cédex Pierre Benite, France

  • 254 trials recruiting
  • Plasma cell myeloma · Non-small cell lung cancer · Acute myeloid leukaemia
  • Adults and children

About Specializations

Centre Hospitalier Lyon Sud in Pierre Benite, France specialises in clinical trials of conditions such as Plasma cell myeloma, Non-small cell lung cancer, Acute myeloid leukaemia, Colitis ulcerative, and other specialisations. This site conducts important research.

Main research areas of the site

Cystic Fibrosis

The medical center is at the forefront of research in Cystic Fibrosis, focusing on the long-term safety and tolerability of innovative therapies. The center's work in this area aims to enhance the quality of life for patients by exploring new treatment combinations.

  • Long-term safety of elexacaftor/tezacaftor/ivacaftor
  • Improving patient outcomes

Through its research, the center contributes significantly to the understanding and management of Cystic Fibrosis, offering hope for improved therapeutic strategies.

Polycythaemia Vera (PV)

Specializing in Polycythaemia Vera, the center conducts pivotal trials comparing the efficacy of ruxolitinib with other therapies. This research is crucial in preventing severe complications and improving survival rates in high-risk patients.

  • Comparative efficacy of ruxolitinib
  • Prevention of major complications

The center's efforts in this field are instrumental in refining treatment protocols and enhancing patient care for those with Polycythaemia Vera.

Lung Cancer, NSCLC

In the realm of Non-Small Cell Lung Cancer (NSCLC), the center is pioneering studies on the efficacy of combination therapies for advanced stages. This research is vital for patients with specific genetic mutations who have progressed after targeted therapies.

  • Combination therapy efficacy
  • Targeted therapy progression

The center's work is pivotal in advancing treatment options and improving outcomes for patients with advanced NSCLC.

Ovarian Cancer

The center is a leader in exploring Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for ovarian cancer relapse. This innovative approach aims to improve survival rates and offers a promising option for patients with resectable relapses.

  • HIPEC efficacy in ovarian cancer
  • Survival rate improvement

Through its research, the center is advancing the treatment landscape for ovarian cancer, providing new hope for patients facing relapse.

Multiple Myeloma

Focusing on Multiple Myeloma, the center is evaluating the efficacy of elranatamab monotherapy in patients resistant to multiple treatment lines. This research is crucial for developing new therapeutic strategies for refractory cases.

  • Elranatamab monotherapy efficacy
  • Refractory multiple myeloma

The center's contributions are vital in expanding treatment options and improving outcomes for patients with Multiple Myeloma.

Sinuses and Salivary Gland Tumors

The center is advancing research in the treatment of sinuses and salivary gland tumors, comparing radiotherapy with chemoradiotherapy. This study aims to optimize treatment regimens and improve progression-free survival for patients.

  • Radiotherapy vs. chemoradiotherapy
  • Progression-free survival

Through its research, the center is enhancing therapeutic approaches and patient outcomes in the treatment of these complex tumors.

Myelofibrosis

In the field of Myelofibrosis, the center is evaluating the combination of pelabresib and ruxolitinib. This research is essential for improving treatment efficacy and offering new hope for patients with this challenging condition.

  • Pelabresib and ruxolitinib combination
  • Improving treatment efficacy

The center's work is crucial in advancing therapeutic options and enhancing the quality of life for patients with Myelofibrosis.

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Site location
165 Chemin du Grand Revoyet, Pavillon Médical Bat 1A, Rhône69494 Cédex Pierre BeniteFrance
Recruiting now
254 trials
Conditions studied
326
Partner status
Verified site

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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655 clinical trials

Obesity+1

Recruiting

A Phase III Study of Lenbelintide in Adults with Obesity or Overweight and Weight‑Related Comorbidity Without Type 2 Diabetes

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:AZD6234
  • Sponsor:AstraZeneca AB
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Golimumab
  • Sponsor:Janssen Cilag International

Randomized Phase III trial of elecoglipron plus dapagliflozin on kidney outcomes and mortality in adults with chronic kidney disease

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

Study of LY4268989 adipic acid in adults with moderately to severely active ulcerative colitis

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Eli Lilly & Co.

Long‑Term Safety and Efficacy of SPY001-001, SPY002 and SPY003 in Adults with Ulcerative Colitis

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:SPY002
  • Sponsor:Spyre Therapeutics Inc.

A Phase 3 Study of Efimosfermin Alfa to Assess Safety and Tolerability in Adults with F2‑F3 Stage Metabolic Dysfunction‑Associated Steatohepatitis (MASH)

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Glaxosmithkline Research & Development Limited

Safety and Efficacy of Efimosfermin Alfa in Participants with Biopsy‑Confirmed F2‑ or F3‑Stage Metabolic Dysfunction‑Associated Steatohepatitis (MASH)

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Glaxosmithkline Research & Development Limited

Phase 3 study of ZL-1310 versus topotecan hydrochloride in patients with relapsed small cell lung cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Topotecan Hydrochloride
  • Sponsor:Zai Lab (US) LLC

A study of loxo-435, enfortumab vedotin, and pembrolizumab in adults with advanced or metastatic bladder cancer

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Enfortumab Vedotin
  • Sponsor:Eli Lilly & Co.

Eczema nummular

Recruiting

A study to evaluate the effectiveness and safety of lebrikizumab in adults with nummular eczema who do not respond well to topical corticosteroids.

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Lebrikizumab
  • Sponsor:Almirall S.A.

A Phase III trial of BI 456906 weekly injections in adults with NASH and stage 2‑3 liver fibrosis

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:BI 456906
  • Sponsor:Boehringer Ingelheim International GmbH

Breast cancer

Recruiting

Study of BNT327 and a drug combination for patients with untreated metastatic or locally recurrent triple-negative breast cancer

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:BioNTech SE
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