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Centre Hospitalier Intercommunal Toulon / La Seine-Sur-Mer

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France 54 Rue Henri Sainte Claire Deville, Cs 91400, 83056 Toulon, France

  • 32 trials recruiting
  • Non-small cell lung cancer · Cardiac failure · Non-small cell lung cancer stage IV
  • Adults and children

About Specializations

Centre Hospitalier Intercommunal Toulon / La Seine-Sur-Mer in Toulon, France specialises in clinical trials of conditions such as Non-small cell lung cancer, Cardiac failure, Non-small cell lung cancer stage IV, Non-small cell lung cancer metastatic, and other specialisations. This site conducts important research.

Main research areas of the site

Oncology

The medical center is at the forefront of oncology research, focusing on innovative treatments for various types of cancer, including Non-Small Cell Lung Cancer (NSCLC) and breast carcinoma. The center's research aims to improve survival rates and quality of life for cancer patients through cutting-edge therapies.

  • Non-Small Cell Lung Cancer (NSCLC)
  • Breast Carcinoma
  • Prostate Cancer

By exploring novel combinations of immunotherapy and chemotherapy, the center is paving the way for more effective cancer treatments.

Cardiology

Specializing in cardiology, the center conducts research on heart failure and septic cardiomyopathy. The focus is on developing therapies that enhance cardiac function and reduce the risk of adverse cardiovascular events.

  • Heart Failure
  • Septic Cardiomyopathy

Through innovative clinical trials, the center is advancing the understanding of heart diseases and improving patient outcomes.

Gastroenterology

The center is renowned for its research in gastroenterology, particularly in the management of inflammatory bowel diseases such as Crohn's Disease and Ulcerative Colitis. The research focuses on optimizing treatment strategies to achieve better disease control.

  • Crohn's Disease
  • Ulcerative Colitis

By integrating patient education and telemonitoring, the center is enhancing the management of these chronic conditions.

Hematology

In the field of hematology, the center is dedicated to improving treatments for blood disorders, including Chronic Lymphocytic Leukemia (CLL). The research aims to develop therapies that target specific genetic mutations to improve patient outcomes.

  • Chronic Lymphocytic Leukemia (CLL)

Through rigorous clinical trials, the center is contributing to the development of personalized medicine approaches in hematology.

Neurology

The center's neurology research focuses on neonatal conditions such as hypoxic-ischaemic encephalopathy. The goal is to explore regenerative therapies that can improve neurological outcomes in affected infants.

  • Neonatal Hypoxic-Ischaemic Encephalopathy

By investigating the use of stem cell therapies, the center is at the cutting edge of neonatal neurological research.

Thrombosis and Hemostasis

Research in thrombosis and hemostasis at the center is focused on improving the management of conditions like venous thromboembolism and deep vein thrombosis. The center is exploring new anticoagulant therapies to enhance patient safety and efficacy.

  • Venous Thromboembolism
  • Deep Vein Thrombosis

Through comprehensive clinical trials, the center is advancing the treatment protocols for thrombotic disorders.

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Site location
54 Rue Henri Sainte Claire Deville, Cs 9140083056 ToulonFrance
Recruiting now
32 trials
Conditions studied
58
Partner status
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Ongoing trials

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71 clinical trials

Phase 3 study of ZL-1310 versus topotecan hydrochloride in patients with relapsed small cell lung cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Topotecan Hydrochloride
  • Sponsor:Zai Lab (US) LLC

Study of BNT327 with etoposide and carboplatin compared to atezolizumab with etoposide and carboplatin for patients with untreated extensive-stage small-cell lung cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Atezolizumab
  • Sponsor:BioNTech SE

Cardiac failure

Recruiting

Study of PF-07328948 tablets compared to placebo in adults with heart failure to evaluate effects on symptoms and physical function

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Pfizer Inc.

Study on the Safety and Effectiveness of BNT327 with Chemotherapy for Patients with Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:BNT327
  • Sponsor:BioNTech SE

Study of LY3537982, pembrolizumab, and a drug combination for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Eli Lilly & Co.

Effect of elecoglipron plus dapagliflozin on cardiovascular outcomes in adults with heart failure with preserved or mildly reduced ejection fraction (HFpEF/HFmrEF)

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

Sepsis

Recruiting

Study of dexmedetomidine and a drug combination for treating patients on mechanical ventilation with septic shock.

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Dexmedetomidine
  • Sponsor:Hospices Civils De Lyon

Cardiac failure+1

Recruiting

Study of Zenagamtide (NNC0487-0111) versus placebo in patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Novo Nordisk A/S

Crohn's disease

Recruiting

One-Year Effectiveness Study of Guselkumab in Adults with Crohn’s Disease

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Guselkumab
  • Sponsor:Groupe D'etude Therapeutique Des Affections Inflammatoires Du Tube Digestif

Neoplasm malignant+1

Recruiting

Anti‑PD1 Therapy with pembrolizumab and cemiplimab in first‑line advanced non‑small cell lung cancer patients with high PD‑L1 expression

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Cemiplimab
  • Sponsor:Unicancer

A study of coramitug compared to placebo for people with heart failure caused by transthyretin amyloid cardiomyopathy

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Novo Nordisk A/S

Study of ivonescimab alone or with ligufalimab versus pembrolizumab for patients with recurrent or metastatic head and neck squamous cell cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Ivonescimab
  • Sponsor:Groupe Oncologie Radiotherapie Tete Cou
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