Centre Hospitalier Intercommunal De Poissy Saint Germain

The Centre Hospitalier Intercommunal De Poissy Saint Germain is conducting research aimed at reducing pregnancy‑related risks. A study evaluates whether routine use of aspirin early in gestation can lower the incidence of preterm preeclampsia among first‑time mothers who conceived through assisted reproductive technology.

• Prevention of preeclampsia
• Impact of early‑pregnancy interventions
• Outcomes after assisted reproductive technology

This work supports improved maternal health and may inform guidelines for obstetric care in France.

Investigators are assessing the long‑term safety of the oral agent tolebrutinib in adults living with multiple sclerosis, including both relapsing and progressive forms. The trial monitors tolerability and potential adverse effects over an extended period.

• Long‑term safety assessment
• Treatment of relapsing multiple sclerosis
• Management of progressive multiple sclerosis
• Real‑world effectiveness

Findings could expand therapeutic options for patients with chronic neuro‑inflammatory disease and guide clinicians across Europe.

The research programme also addresses broader clinical concerns by tracking adverse events and symptom patterns in participants from both obstetric and neurology studies, ensuring comprehensive safety surveillance.

• Monitoring of clinical signs
• Reporting of adverse events
• Integration of safety data across specialties
• Patient‑reported outcome measures

This cross‑disciplinary approach enhances the centre’s capacity to protect participants and generate robust evidence for health policy.