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Centre Hospitalier Departemental Vendee

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France Boulevard Stephane Moreau, 85925 La Roche sur Yon, France

  • 87 trials recruiting
  • Plasma cell myeloma · Breast cancer · Non-small cell lung cancer
  • Adults and children

About Specializations

Centre Hospitalier Departemental Vendee in La Roche sur Yon, France specialises in clinical trials of conditions such as Plasma cell myeloma, Breast cancer, Non-small cell lung cancer, Colitis ulcerative, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Medicine

The center is at the forefront of cardiovascular medicine, focusing on innovative treatments for acute myocardial infarction. The AMUNDSEN-real trial exemplifies our commitment to advancing therapeutic strategies, particularly in the use of evolocumab to achieve significant LDL-C reduction.

  • Acute Myocardial Infarction
  • LDL-C Management
  • Innovative Lipid-Lowering Therapies

Our research contributes to the development of personalized treatment plans that enhance patient outcomes in real-world settings.

Respiratory Medicine

Our center excels in respiratory medicine, with a particular emphasis on Chronic Pulmonary Aspergillosis. Through trials like CPAAARI, we explore the efficacy of combined antifungal therapies, enhancing treatment protocols for non-immunocompromised patients.

  • Chronic Pulmonary Aspergillosis
  • Antifungal Therapy
  • Respiratory Infections

Our work aims to refine therapeutic approaches, improving both clinical and radiological outcomes for patients.

Oncology

In the field of oncology, our center is pioneering research in multiple myeloma and other hematological malignancies. The IFM2020-05-BENEFIT study highlights our efforts in evaluating novel drug combinations to improve Minimal Residual Disease rates.

  • Multiple Myeloma
  • Hematological Malignancies
  • Novel Drug Combinations

Our research is instrumental in developing targeted therapies that offer hope for better management of these complex conditions.

Endocrinology

Our center is advancing the field of endocrinology through studies like the post-thyroidectomy hypocalcemia trial, which investigates the role of cholecalciferol supplementation in preventing complications after thyroid surgery.

  • Thyroid Disorders
  • Postoperative Care
  • Vitamin D Supplementation

We aim to enhance surgical outcomes and patient comfort through innovative preoperative strategies.

Rheumatology

In rheumatology, our center is exploring advanced treatment options for rheumatoid arthritis. Trials like the combination of methotrexate with targeted therapies are pivotal in improving patient response and quality of life.

  • Rheumatoid Arthritis
  • Targeted Therapies
  • Combination Treatments

Our research is dedicated to finding more effective and personalized treatment regimens for chronic inflammatory conditions.

Nephrology

Our center is a leader in nephrology, focusing on innovative treatments for renal cell carcinoma and other kidney-related conditions. Studies comparing tivozanib combinations are crucial in enhancing therapeutic efficacy.

  • Renal Cell Carcinoma
  • Kidney Health
  • Targeted Cancer Therapies

We strive to improve survival rates and quality of life for patients with advanced kidney diseases.

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Site location
Boulevard Stephane Moreau85925 La Roche sur YonFrance
Recruiting now
87 trials
Conditions studied
149
Partner status
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Ongoing trials

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208 clinical trials

Crohn's disease

Recruiting

Study of RO7790121 (afimkibart) for Treatment and Long-term Management in Adults with Moderate to Severe Crohn's Disease

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:RO7790121
  • Sponsor:F. Hoffmann-La Roche AG
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:Astrazeneca AB

Study on the Effects of Baxdrostat and Dapagliflozin in Adults with Chronic Kidney Disease and High Blood Pressure

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:Astrazeneca AB

Study on Eltrekibart and Mirikizumab for Adults with Moderate to Severe Ulcerative Colitis

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Mirikizumab
  • Sponsor:Eli Lilly & Co.

Study on Selatogrel for Preventing Heart Attack in Patients with Recent Heart Attack History

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Selatogrel
  • Sponsor:Viatris Innovation GmbH

Asthma

Recruiting

Study of Beclometasone Dipropionate in Patients with Asthma to Evaluate Disease Characteristics and Control

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Beclometasone Dipropionate
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Safety and Tolerability of Alisertib Sodium and Paclitaxel in Patients with Small Cell Lung Cancer (Phase 2 Study)

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Alisertib Sodium
  • Sponsor:Puma Biotechnology Inc.

Crohn's disease

Recruiting

One-Year Effectiveness Study of Guselkumab in Adults with Crohn’s Disease

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Guselkumab
  • Sponsor:Groupe D'etude Therapeutique Des Affections Inflammatoires Du Tube Digestif

Comparing sotorasib and pembrolizumab with chemotherapy for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Amgen Inc.

Efficacy and Safety of Subcutaneous Belimumab in Adults with Connective Tissue Disease-Associated Interstitial Lung Disease

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Belimumab
  • Sponsor:Glaxosmithkline Research & Development Limited

A study testing how well AZD4144 works and how safe it is for adults with acute kidney injury caused by sepsis

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Astrazeneca AB

A study of coramitug compared to placebo for people with heart failure caused by transthyretin amyloid cardiomyopathy

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Novo Nordisk A/S
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