Rare diseases
Investigational molecules
Locations
Dokter Stolteweg 90, 8025 AZ Zwolle, The Netherlands
Brain Research Center Zwolle B.V. in Zwolle, The Netherlands specialises in clinical trials of conditions such as Dementia Alzheimer's type, Parkinson's disease, Cardiovascular disorder, Dementia, and other specialisations. This site conducts important research.
At Brain Research Center Zwolle B.V., the strongest focus is on nervous system diseases, especially Alzheimer’s disease and related forms of cognitive decline. The trials are designed to test new treatment options, assess symptom improvement, and better understand how therapies may affect memory and daily functioning in people with early and mild to moderate disease.
Several studies also look at biomarkers and brain changes, helping researchers evaluate whether treatments are affecting the underlying disease process.
The site is also active in neurology research for Parkinson’s disease, including early-stage disease. These trials aim to evaluate whether investigational treatments can slow progression, preserve motor function, and support long-term disease control.
This work reflects a broader effort in nervous system diseases to find therapies that may change the course of chronic neurodegenerative illness.
Research at this laboratory and testing facility also includes cardiovascular diseases and nutritional and metabolic diseases. Current trials focus on reducing the risk of heart failure and cardiovascular death, while also studying conditions linked to type 2 diabetes, hypertension, and established cardiovascular disease.
These studies aim to improve treatment effectiveness for people with overlapping metabolic and heart-related conditions.
The Zwolle site contributes to research on how brain diseases can be tracked and treated more precisely, including studies in mental disorders and broader nervous system diseases. A number of trials examine biomarkers, imaging findings, and clinical progression to support earlier diagnosis and more targeted care.
This research helps connect clinical symptoms with biological changes, offering a clearer picture of how different therapies may work in practice.
More sites in ZwolleThe Netherlands
Clinical trials currently enrolling participants at this site.
Efficacy and safety of oral semaglutide for weight loss in adults with overweight or obesity
The NetherlandsStudy of vicadrostat and empagliflozin combination in patients with type 2 diabetes, high blood pressure and cardiovascular disease
The NetherlandsStudy of VHB937 to evaluate its effects on cognition and function in people with early Alzheimer's Disease over 72 weeks
The NetherlandsThe NetherlandsN1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD
The NetherlandsA study comparing prasinezumab with placebo for people with early-stage Parkinson's disease
The NetherlandsStudy of KarXT (trospium chloride and xanomeline tartrate) and KarX-EC (xanomeline tartrate) for cognitive impairment in mild to moderate Alzheimer's disease
The NetherlandsStudy of xanomeline tartrate and trospium chloride combination for cognitive impairment in people with mild to moderate Alzheimer's disease
The NetherlandsStudy of MK-2214 to slow disease progression in people with early Alzheimer's disease
The NetherlandsA Phase II Randomized, Double‑Blind Study of RO7568282 for Safety and Efficacy in Early‑Stage Parkinson’s Disease Patients
The NetherlandsStudy on the Safety and Effectiveness of PRI-002 for Patients with Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease
The NetherlandsStudy on Donanemab, Florbetapir, and Flortaucipir for Patients with Early Alzheimer's Disease
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