Rare diseases
Investigational molecules
Locations
Cronenburg 2, 1081 GN Amsterdam, The Netherlands
Brain Research Center Amsterdam B.V. in Amsterdam, The Netherlands specialises in clinical trials of conditions such as Dementia Alzheimer's type, Parkinson's disease, Cardiovascular disorder, Cerebral amyloid angiopathy, and other specialisations. This site conducts important research.
At Brain Research Center Amsterdam B.V., a major share of the clinical research focuses on Nervous System Diseases, especially Alzheimer’s disease and related cognitive disorders. These studies are designed to test new therapies, track disease-related biomarkers, and better understand how to slow memory and thinking decline.
The research includes efforts to improve treatment effectiveness and identify measurable signs of brain change that may support earlier and more precise care.
The site also runs trials in Parkinson’s disease, reflecting its strong focus on neurology and movement-related disorders. These studies aim to evaluate whether new treatments can help slow symptom worsening and support daily functioning in people living with early-stage disease.
This work helps explore whether emerging therapies can improve long-term disease control and quality of life.
Alongside brain-focused studies, the center participates in trials on cardiovascular diseases, including heart failure, hypertension, and broader cardiovascular disease risk. These trials are intended to assess whether new treatment approaches can reduce serious heart-related events and improve prevention.
The research supports better strategies for patients with overlapping metabolic and heart conditions.
Clinical trials at this Amsterdam site also cover Psychiatry and Psychology, with a focus on major depressive disorder and cognitive symptoms linked to brain disease. These studies are aimed at evaluating new options that may improve mood, thinking, and everyday functioning.
This area adds an important mental health dimension to the center’s broader neurological research portfolio.
More sites in AmsterdamThe Netherlands
Clinical trials currently enrolling participants at this site.
Efficacy and safety of oral semaglutide for weight loss in adults with overweight or obesity
The NetherlandsStudy of vicadrostat and empagliflozin combination in patients with type 2 diabetes, high blood pressure and cardiovascular disease
The NetherlandsStudy of VHB937 to evaluate its effects on cognition and function in people with early Alzheimer's Disease over 72 weeks
The NetherlandsThe NetherlandsA study comparing prasinezumab with placebo for people with early-stage Parkinson's disease
The NetherlandsStudy of KarXT (trospium chloride and xanomeline tartrate) and KarX-EC (xanomeline tartrate) for cognitive impairment in mild to moderate Alzheimer's disease
The NetherlandsStudy of xanomeline tartrate and trospium chloride combination for cognitive impairment in people with mild to moderate Alzheimer's disease
The NetherlandsSafety and Tolerability Study of NBI-1065845 as Additional Treatment for Adults with Major Depressive Disorder
The NetherlandsStudy of MK-2214 to slow disease progression in people with early Alzheimer's disease
The NetherlandsStudy on Efavirenz for Patients with Early Alzheimer's Disease
The NetherlandsPhase 3 Randomized, Double‑Blind Study of Telitacicept versus Placebo for Efficacy and Safety in Adults with Active Primary Sjögren’s Disease
The NetherlandsA study to test if BHV-8000 is effective and safe for adults with early Parkinson's disease
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