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Barmherzige Brueder gemeinnuetzige Krankenhaus GmbH

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Germany Pruefeninger Strasse 86, Westenviertel, 93049 Regensburg, Germany

  • 27 trials recruiting
  • Chronic lymphocytic leukaemia · Oesophageal adenocarcinoma · Plasma cell myeloma
  • Adults and children

About Specializations

Barmherzige Brueder gemeinnuetzige Krankenhaus GmbH in Regensburg, Germany specialises in clinical trials of conditions such as Chronic lymphocytic leukaemia, Oesophageal adenocarcinoma, Plasma cell myeloma, Acute myeloid leukaemia, and other specialisations. This site conducts important research.

Main research areas of the site

Hemic and Lymphatic Diseases

The Clinic for Oncology and Hematology at Barmherzige Brueder gemeinnuetzige Krankenhaus GmbH in Regensburg is active in hematologic cancer research, with studies focused on diseases such as acute myeloid leukemia, chronic lymphocytic leukemia, multiple myeloma, and several forms of lymphoma. These trials are mainly designed to improve treatment effectiveness, deepen remission, and refine long-term disease control.

  • Research in acute leukemia includes new treatment combinations for acute myeloid leukemia and acute lymphoblastic leukemia.
  • Studies in chronic leukemias and lymphoid cancers examine better ways to manage CLL, SLL, mantle cell lymphoma, and follicular lymphoma.
  • Myeloma trials evaluate approaches intended to strengthen response depth and sustain disease control in multiple myeloma.

Overall, this site contributes to advancing blood cancer care by testing therapies that may improve survival, response quality, and treatment tolerability.

Neoplasms

Another major focus at the Regensburg site is solid tumor research, especially cancers of the stomach, gastroesophageal junction, colon, rectum, esophagus, lung, and ovary. The studies aim to test new treatment strategies, improve survival, and support better outcomes before and after surgery.

  • Gastroesophageal and gastric cancers are being studied through trials of combined systemic and perioperative treatment approaches.
  • Colorectal and rectal cancer studies explore ways to improve disease-free survival and preserve organ function.
  • Lung cancer, pleural mesothelioma, and other advanced solid tumors are included in trials evaluating newer immunotherapy-based strategies.

These studies reflect a broad effort to improve both curative and advanced cancer care through more effective and personalized treatment options.

Digestive System Diseases

The site also conducts research in digestive system diseases, with a strong emphasis on cancers and inflammatory conditions affecting the colon, rectum, stomach, and esophagus, as well as ulcerative colitis. The main purpose is to evaluate better therapies, improve recovery after treatment, and support more precise care decisions.

  • Colorectal cancer trials examine preoperative, postoperative, and organ-preserving treatment strategies.
  • Upper gastrointestinal cancer studies assess approaches for gastric and esophagogastric adenocarcinoma.
  • Inflammatory bowel disease research includes work in ulcerative colitis to improve symptom control and remission.

These efforts show a clear interest in both cancer care and chronic digestive disease management.

Respiratory Tract Diseases

Within respiratory tract disease research, the site is involved in studies of non-small cell lung cancer, pleural mesothelioma, and interstitial lung disease linked to autoimmune conditions. The trials are designed to test improved treatments, measure disease control, and better understand outcomes in difficult-to-treat lung-related illnesses.

  • Stage III unresectable NSCLC studies evaluate new combinations intended to delay progression.
  • Pleural mesothelioma trials focus on extending survival and improving response in advanced disease.
  • Interstitial lung disease research looks at reducing lung involvement and improving respiratory health.

This area highlights the center’s involvement in both thoracic oncology and non-malignant lung disease research.

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

In addition to cancer-focused work, the Barmherzige Brueder gemeinnuetzige Krankenhaus GmbH participates in research on congenital and neonatal conditions, including fetal heart development disorders. These studies aim to improve early diagnosis and support better outcomes for unborn babies with structural abnormalities.

  • Fetal cardiac development research addresses underdeveloped structures on the left side of the heart.
  • Trial objectives center on improving prenatal care and evaluating whether treatment during pregnancy can support growth and development.
  • This work adds a maternal-fetal medicine dimension to the site’s broader clinical research portfolio.

Although smaller in scope, this area shows the site’s interest in conditions that begin before birth and may benefit from earlier intervention.

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Site location
Pruefeninger Strasse 86, Westenviertel93049 RegensburgGermany
Recruiting now
27 trials
Conditions studied
50
Partner status
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Ongoing trials

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52 clinical trials

Adjuvant Therapy with RO7435846 (divarasib) versus Pembrolizumab or Nivolumab or Observation in Patients After Surgery for Stage II‑III KRAS G12C NSCLC

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Divarasib
  • Sponsor:F. Hoffmann-La Roche AG

Study of AZD0486 plus rituximab versus standard chemotherapy drug combination in previously untreated follicular lymphoma patients

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Cyclophosphamide
  • Sponsor:AstraZeneca AB

Accelerating improvement with teclistamab plus standard drug combination in newly diagnosed transplant‑eligible multiple myeloma patients

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bortezomib
  • Sponsor:Universitaetsklinikum Heidelberg AöR

Long-Term Safety Study of Asciminib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Bosutinib
  • Sponsor:Novartis Pharma AG

Neoplasm

Recruiting

Volrustomig in Patients with Unresectable Pleural Mesothelioma and Esophageal Squamous Cell Carcinoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:Cisplatin
  • Sponsor:AstraZeneca AB
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Ascorbic Acid
  • Sponsor:Norgine Limited

Testing icotrokinra compared to placebo for adults and adolescents with moderately to severely active ulcerative colitis

Investigational
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Icotrokinra
  • Sponsor:Janssen Cilag International

Study of zanidatamab with drug combination for patients with HER2 and PD-L1 positive advanced gastroesophageal cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Fluorouracil
  • Sponsor:Frankfurter Institut Fuer Klinische Krebsforschung IKF GmbH

A Study of BMS-986504 with Drug Combination Compared to Placebo with Drug Combination in Patients with Advanced Non-Small Cell Lung Cancer Starting First Treatment

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Study of ivosidenib maintenance treatment in patients with IDH1-mutated cholangiocarcinoma after standard chemotherapy

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Ivosidenib
  • Sponsor:Frankfurter Institut Fuer Klinische Krebsforschung IKF GmbH

Study on Venetoclax, Obinutuzumab, and Pirtobrutinib for Patients with Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Obinutuzumab
  • Sponsor:University Of Cologne

Pancreatectomy

Recruiting

Study on Hydrocortisone for Patients Undergoing Pancreatic Surgery

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Hydrocortisone
  • Sponsor:Universitaetsklinikum Schleswig-Holstein AöR
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