Azienda Ospedaliera Specialistica dei Colli – Ospedale Monaldi

At Azienda Ospedaliera Specialistica dei Colli – Ospedale Monaldi, investigators are focusing on severe cardiac inflammation, particularly acute myocarditis, aiming to improve outcomes with innovative treatment strategies.

• Acute myocarditis management
• Pulsed corticosteroid therapy
• Reduction of primary composite endpoint
• Optimization of supportive care

The work seeks to lower mortality and complications in patients with fulminant cardiac inflammation, contributing valuable data for future cardiac care guidelines.

The cardiology department also supports oncology studies targeting HR+/HER2- breast cancer, evaluating new therapeutic combos after resistance to earlier regimens.

• CDK4/6 inhibitor resistance
• Sequencing of hormonal therapies
• Efficacy of palbociclib
• Safety of fulvestrant in metastatic disease

By testing palbociclib plus fulvestrant, researchers aim to expand effective options for women with locally advanced or metastatic disease who have progressed on prior treatments.