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Azienda Ospedaliera Nazionale Ss Antonio E Biagio E C Arrigo Alessandria

Verified siteinfo

Italy Via Venezia 16, 15121 Alexandria, Italy

  • 57 trials recruiting
  • Diffuse large B-cell lymphoma · Chronic lymphocytic leukaemia · Follicular lymphoma
  • Adults and children

About Specializations

Azienda Ospedaliera Nazionale Ss Antonio E Biagio E C Arrigo Alessandria in Alexandria, Italy specialises in clinical trials of conditions such as Diffuse large B-cell lymphoma, Chronic lymphocytic leukaemia, Follicular lymphoma, Myelofibrosis, and other specialisations. This site conducts important research.

Main research areas of the site

Cardiovascular Diseases

At Azienda Ospedaliera Nazionale Ss Antonio E Biagio E C Arrigo Alessandria, cardiovascular research focuses on preventing major heart and stroke events in people with acute coronary syndrome. These studies are designed to test whether new treatment approaches can improve protection beyond standard care.

  • Reducing the risk of cardiovascular death, heart attack, and ischemic stroke
  • Evaluating a new therapy added to usual treatment after a cardiac event

This work reflects a strong interest in better long-term outcomes for patients with serious heart disease.

Neoplasms and Hemic/Lymphatic Diseases

Much of the clinical trial activity at this site centers on lymphomas and other blood cancers, including diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and multiple myeloma. The research aims to improve treatment effectiveness, support patients who are less fit for standard therapy, and explore better ways to control relapsed or newly diagnosed disease.

  • Testing new immunotherapy and antibody-based treatments for lymphoma
  • Studying response-adapted care for patients with newly diagnosed or hard-to-treat blood cancers
  • Evaluating treatment options for relapsed or refractory multiple myeloma

These studies highlight the site’s active role in advancing care across aggressive and indolent hematologic malignancies.

Digestive System Diseases and Inflammatory Conditions

Clinical research here also includes ulcerative colitis, with trials focused on improving clinical remission for people living with chronic intestinal inflammation. The goal is to assess whether new treatments can better control symptoms and support longer-lasting disease management.

  • Evaluating a new therapy for ulcerative colitis
  • Comparing its ability to achieve and maintain clinical remission

These studies add an important gastroenterology dimension to the site’s broader research portfolio.

Nutritional and Metabolic Diseases

In the area of gout with hyperuricemia, the site is involved in research aimed at lowering uric acid levels more effectively. This work is intended to compare a new treatment approach with established care and improve symptom control for patients affected by metabolic complications.

  • Comparing treatments for better uric acid reduction
  • Supporting improved management of gout and related metabolic risk

Such studies help refine everyday treatment strategies for a common and painful chronic condition.

Pathological Conditions, Signs and Symptoms

This research area includes studies on reversing the effects of factor Xa inhibitors in patients who need urgent surgery and face a major bleeding risk. The objective is to evaluate whether a targeted treatment can help control bleeding more effectively than usual care in emergency settings.

  • Assessing rapid reversal of anticoagulation-related bleeding risk
  • Supporting safer urgent procedures for patients on blood thinners

These trials address a practical hospital need and may improve emergency management for high-risk patients.

Musculoskeletal Diseases

The site also contributes to research in musculoskeletal disease, particularly by studying conditions such as gout that affect joints and mobility. The aim is to improve symptom relief and long-term disease control through better treatment options.

  • Improving care for joint-related complications linked to gout
  • Comparing treatments that may reduce inflammation and discomfort

This work supports more effective management of painful conditions that can interfere with daily activity.

Health Care and Public Health

Some of the research at this hospital addresses broader health care needs, including safer treatment pathways and better support for patients with complex conditions. These studies focus on practical improvements that can strengthen care delivery in real-world clinical settings.

  • Improving safety in urgent and high-risk hospital care
  • Testing new approaches that may enhance treatment effectiveness across specialties

By combining specialty research with applied health care questions, the site contributes to both individual patient care and broader clinical practice.

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Site location
Via Venezia 1615121 AlexandriaItaly
Recruiting now
57 trials
Conditions studied
100
Partner status
Verified site

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Clinical trials currently enrolling participants at this site.

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132 clinical trials

Randomized Phase III trial of elecoglipron plus dapagliflozin on kidney outcomes and mortality in adults with chronic kidney disease

Registered drug
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Baxdrostat
  • Sponsor:AstraZeneca AB

Study of belumosudil versus drug combination in patients aged 12 years and older with chronic graft‑versus‑host disease refractory after prior therapy

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Bortezomib
  • Sponsor:Sanofi-Aventis Recherche & Developpement

A Phase 3 Study of Sapablursen Compared with Placebo in Adults with Polycythemia Vera

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Sapablursen
  • Sponsor:Deciphera Pharmaceuticals Inc.

Phase 1/2 Study Evaluating Safety and Activity of GSK5926371 in Adults with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

InvestigationalNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Sponsor:Glaxosmithkline Research & Development Limited

Efficacy and safety of lunsekimig in adults with inadequately controlled eosinophilic COPD: a randomized, double‑blind, placebo‑controlled trial

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Lunsekimig
  • Sponsor:Sanofi-Aventis Recherche & Developpement

JNJ-79635322 versus Teclistamab in Patients with Relapsed or Refractory Multiple Myeloma After at Least 3 Prior Treatments

InvestigationalNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Teclistamab
  • Sponsor:Janssen Cilag International

Neoplasm

Recruiting

Volrustomig in Patients with Unresectable Pleural Mesothelioma and Esophageal Squamous Cell Carcinoma

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years
  • Substances:Cisplatin
  • Sponsor:AstraZeneca AB

A study of PM54 and pembrolizumab in adults with advanced cancer

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:Pharma Mar S.A.

Study of glofitamab, obinutuzumab and tocilizumab in patients with mantle cell lymphoma relapsed or refractory after CAR‑T therapy

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Glofitamab
  • Sponsor:Fondazione Italiana Linfomi Ets

A study to compare glofitamab against a drug combination for patients with relapsed or refractory mantle cell lymphoma

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Glofitamab
  • Sponsor:F. Hoffmann-La Roche AG

A study to evaluate the effectiveness of R2R01 in preventing acute kidney injury in patients at high risk following heart surgery.

Registered drug
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:R2R01
  • Sponsor:River 2 Renal Corp.
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