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ASST Ospedale Maggiore di Crema

Italy Largo Ugo Dossena, 2, 26013 Crema, Italy

  • Oesophageal adenocarcinoma · Non-small cell lung cancer · Metastatic malignant melanoma
  • Adult patients

About Specializations

ASST Ospedale Maggiore di Crema in Crema, Italy specialises in clinical trials of conditions such as Oesophageal adenocarcinoma, Non-small cell lung cancer, Metastatic malignant melanoma, and other specialisations. This site conducts important research.

Main research areas of the site

Digestive System Oncology

The ASST Ospedale Maggiore di Crema is conducting research focused on advanced HER2‑negative and PD‑L1 positive gastroesophageal adenocarcinoma, aiming to improve outcomes through a switch‑maintenance strategy that combines chemotherapy and immunotherapy.

  • Evaluation of paclitaxel as part of maintenance therapy
  • Role of ramucirumab in anti‑angiogenic treatment
  • Use of tislelizumab to enhance immune response
  • Impact of HER2‑negative status on therapeutic choices
  • Significance of PD‑L1 positive biomarkers

Findings aim to extend progression‑free survival for patients with this digestive system cancer.

Melanoma Immunotherapy

In the field of skin cancer, the site is evaluating a novel antibody, ABP 206, against the established checkpoint inhibitor nivolumab for patients with unresectable or metastatic melanoma who have not received prior systemic therapy.

  • Comparison of ABP 206 with standard immunotherapy
  • Assessment of response in first‑line treatment setting
  • Investigation of immune checkpoint inhibition mechanisms
  • Monitoring of safety and tolerability profiles
  • Exploration of biomarkers predictive of benefit

The study seeks to determine whether the new agent can provide a more effective treatment option for patients with advanced melanoma.

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Site location
Largo Ugo Dossena, 226013 CremaItaly
Recruiting now
no trials
Conditions studied
3

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Ongoing trials

Clinical trials registered at this site – none is enrolling right now.

Condition
Type of trial
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Quick filters

3 clinical trials

Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Fondazione GONO G.I.
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Universita' Vita-salute S. Raffaele
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Nivolumab
  • Sponsor:Amgen Inc.
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