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Assistance Publique Hopitaux De Paris

Research site

France 104 Boulevard Raymond Poincare, 92380 Garches, France

  • 20 trials recruiting
  • Sepsis · Ischaemic stroke · Myasthenia gravis
  • Adults and children

About Specializations

Assistance Publique Hopitaux De Paris in Garches, France specialises in clinical trials of conditions such as Sepsis, Ischaemic stroke, Myasthenia gravis, Haemophagocytic lymphohistiocytosis, and other specialisations. This site conducts important research.

Main research areas of the site

Immune System Diseases

The Service de Neurologie at Assistance Publique Hopitaux De Paris is conducting research focused on managing prolonged immune suppression in critically ill patients.

  • Evaluating interferon‑gamma therapy to reduce secondary infections in ICU patients
  • Assessing safety and immunological outcomes of standardized immunotherapy

This work aims to improve infection prevention strategies and enhance patient recovery in intensive care settings.

Nervous System Diseases

Clinical investigations at the neurology department target Spinal Muscular Atrophy, exploring novel treatments for motor function preservation.

  • Testing the efficacy of salanersen (BIIB115) in treatment‑naïve and previously treated SMA participants
  • Monitoring movement outcomes and safety across a wide age range

The goal is to provide new therapeutic options that can improve quality of life for individuals living with SMA.

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Site location
104 Boulevard Raymond Poincare92380 GarchesFrance
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Recruiting now
20 trials
Conditions studied
24

More sites in GarchesFrance

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Ongoing trials

Clinical trials currently enrolling participants at this site.

Condition
Type of trial
Recruitment status
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34 clinical trials

Craniocerebral injury

Recruiting

Phase 2a Study of Safety, Tolerability and Efficacy of Intranasal Cenegermin in Adults with Moderate to Severe Subacute Traumatic Brain Injury

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Cenegermin
  • Sponsor:Dompe' Farmaceutici S.p.A.

Myotonic dystrophy

Recruiting

A study to evaluate the efficacy and safety of DYNE-101 in patients with Myotonic Dystrophy Type 1

Registered drug
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years
  • Substances:Humanised Igg1 Kappa Fragment Antibody Targeting Tfr1 Conjugated To P125 Oligonucleotide
  • Sponsor:Dyne Therapeutics Inc.

Sepsis

Recruiting

Study of dexmedetomidine and a drug combination for treating patients on mechanical ventilation with septic shock.

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Dexmedetomidine
  • Sponsor:Hospices Civils De Lyon

Sepsis

Recruiting

Testing a Drug Combination for Personalized Sepsis Treatment in Children and Adults with Severe Blood Infection

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Anakinra
  • Sponsor:Assistance Publique Hopitaux De Paris

Pathogen resistance

Recruiting

Study of Oral Fecal Microbiota Transplantation in Patients Colonized with Multi-Drug Resistant Bacteria

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Placebo
  • Sponsor:Assistance Publique Hopitaux De Paris

Infection prophylaxis

Recruiting

Study on Preventing Infections in ICU Patients with Interferon Gamma and Sodium Chloride

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:Centre Hospitalier Et Universitaire De Limoges

Study on How Nusinersen is Processed in Adults and Children with Spinal Muscular Atrophy Using the ThecaFlex DRx System

Recruiting
Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Nusinersen
  • Sponsor:Biogen Idec Research Limited

Critical illness

Recruiting

Study on the Effects of Testosterone Gel on Physical Performance in Critically Ill Patients Requiring Long-Term Mechanical Ventilation

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Placebo
  • Sponsor:University Hospital Of Clermont-Ferrand

Tuberculosis

Recruiting

Study on the Effects of Tedizolid and Linezolid for Patients with Suspected Lung Tuberculosis

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Ethambutol
  • Sponsor:Assistance Publique Hopitaux De Paris

Respiratory distress

Recruiting

Study on the Effect of Rocuronium Bromide, Sugammadex, and Suxamethonium Chloride for Adults with Respiratory Distress Requiring Emergency Tracheal Intubation

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Rocuronium Bromide
  • Sponsor:Centre Hospitalier Universitaire De Bordeaux

Staphylococcal infection

Recruiting

Study Comparing Dalbavancin to Standard Antibiotics for Patients with Staphylococcus aureus Bloodstream Infections

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Amikacin Sulfate
  • Sponsor:Assistance Publique Hopitaux De Paris

Ischaemic stroke

Recruiting

Study on Colchicine and Ticagrelor for Preventing Ischemic Stroke in Patients with Atherosclerosis

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Colchicine
  • Sponsor:Assistance Publique Hopitaux De Paris
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