Therapeutic area

Nervous system disorders – page 72

1 397 clinical trials
586 recruiting
459 conditions
29 countries

Clinical trials in Nervous system disorders

1 397 trials across Europe, recruiting first

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1 397 clinical trials

Multiple sclerosis+1

Not recruiting

Phase 1 study of remibrutinib exposure in cerebrospinal fluid after oral dosing in healthy participants

Investigational

Phase 1 study of remibrutinib exposure in cerebrospinal fluid after oral dosing in healthy participants

Investigational

The Netherlands

Participants:18–64 years · Healthy volunteers
Substances:Remibrutinib
Sponsor:Novartis Pharma AG

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Prophylaxis against motion sickness+1

Not recruiting

Bioavailability of 50 mg dimenhydrinate granules taken with or without water versus reference formulations for nausea and vomiting in healthy volunteers

Registered drugNo placebo

Bioavailability of 50 mg dimenhydrinate granules taken with or without water versus reference formulations for nausea and vomiting in healthy volunteers

Registered drugNo placebo

Bulgaria

Participants:18–64 years · Healthy volunteers
Substances:Dimenhydrinate
Sponsor:CCDRD Cooperative Clinical Drug Research and Development AG

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Post-traumatic epilepsy+1

Not recruiting

Pharmacokinetic Study of Oral Marimastat (PKL-021) and Heparin Sodium in Healthy Adult Subjects

Registered drugNo placebo

Pharmacokinetic Study of Oral Marimastat (PKL-021) and Heparin Sodium in Healthy Adult Subjects

Registered drugNo placebo

Czechia

Participants:18–64 years · Healthy volunteers
Substances:Heparin Sodium
Sponsor:Pikralida Sp. z o.o.

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A study to compare how the body absorbs perampanel in healthy adult men and women during fasting conditions

Not recruiting

Registered drugNo placebo

A study to compare how the body absorbs perampanel in healthy adult men and women during fasting conditions

Registered drugNo placebo

Czechia

Participants:18–64 years · Healthy volunteers
Substances:Perampanel
Sponsor:Laboratorios Cinfa S.A.

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Angelman's syndrome

Not recruiting

A Study Testing the Safety and How Well GTX-102 Works in Adults and Children with Angelman Syndrome

InvestigationalNo placebo

A Study Testing the Safety and How Well GTX-102 Works in Adults and Children with Angelman Syndrome

InvestigationalNo placebo

France

Participants:0–17 years · 18–64 years
Substances:Apazunersen
Sponsor:Ultragenyx Pharmaceutical Inc.

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Dementia Alzheimer's type

Not recruiting

Study of Trontinemab Compared to Placebo for Patients with Early Symptomatic Alzheimer's Disease

Registered drug

Study of Trontinemab Compared to Placebo for Patients with Early Symptomatic Alzheimer's Disease

Registered drug

Denmark

Participants:18–64 years · 65+ years
Substances:Florbetaben (18F)
Sponsor:F. Hoffmann-La Roche AG

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Dementia Alzheimer's type

Not recruiting

A study testing trontinemab compared to placebo in patients with early Alzheimer's disease including mild cognitive impairment and mild dementia

Registered drug

A study testing trontinemab compared to placebo in patients with early Alzheimer's disease including mild cognitive impairment and mild dementia

Registered drug

Denmark

Participants:18–64 years · 65+ years
Substances:Florbetaben (18F)
Sponsor:F. Hoffmann-La Roche AG

Contact Research Centre

Multiple sclerosis

Not recruiting

A Study Comparing Two Forms of Ocrelizumab Given Under the Skin in Patients with Multiple Sclerosis

Registered drugNo placebo

A Study Comparing Two Forms of Ocrelizumab Given Under the Skin in Patients with Multiple Sclerosis

Registered drugNo placebo

France

Participants:18–64 years
Substances:Ocrelizumab
Sponsor:F. Hoffmann-La Roche AG

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Dementia Alzheimer's type

Not recruiting

A study testing MK-1167 added to current treatment in patients with mild to moderate Alzheimer's disease dementia

Investigational

A study testing MK-1167 added to current treatment in patients with mild to moderate Alzheimer's disease dementia

Investigational

Italy

Participants:18–64 years · 65+ years
Substances:MK-1167
Sponsor:Merck Sharp & Dohme LLC

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Muscle spasticity

Not recruiting

Comparing Abobotulinumtoxin A and Onabotulinumtoxin A for Adults with Upper Limb Spasticity

Registered drugNo placebo

Comparing Abobotulinumtoxin A and Onabotulinumtoxin A for Adults with Upper Limb Spasticity

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Botulinum Toxin Type A
Sponsor:Ipsen Pharma

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Migraine

Not recruiting

Study of Erenumab Compared to Placebo for Children and Adolescents with Episodic Migraine to Reduce Monthly Migraine Days

Investigational

Study of Erenumab Compared to Placebo for Children and Adolescents with Episodic Migraine to Reduce Monthly Migraine Days

Investigational

Belgium

Participants:0–17 years
Substances:Erenumab
Sponsor:Amgen Inc.

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Migraine

Not recruiting

A Study of Erenumab Compared to Placebo for Children and Teenagers With Chronic Migraine to Test How Well It Works and How Safe It Is

Investigational

A Study of Erenumab Compared to Placebo for Children and Teenagers With Chronic Migraine to Test How Well It Works and How Safe It Is

Investigational

Belgium

Participants:0–17 years
Substances:Erenumab
Sponsor:Amgen Inc.

Contact Research Centre

Substances studied in this area

The therapies tested most often in Nervous system disorders trials.

Sodium Chloride71 clinical trials Temozolomide38 clinical trials Ocrelizumab33 clinical trials Rituximab27 clinical trials Cyclophosphamide24 clinical trials Paracetamol24 clinical trials Methylprednisolone15 clinical trials Prednisolone15 clinical trials Carboplatin14 clinical trials

Nervous system disorders – page 72

Conditions in this area

Clinical trials in Nervous system disorders

1 397 clinical trials

Multiple sclerosis+1

Phase 1 study of remibrutinib exposure in cerebrospinal fluid after oral dosing in healthy participants

Prophylaxis against motion sickness+1

Bioavailability of 50 mg dimenhydrinate granules taken with or without water versus reference formulations for nausea and vomiting in healthy volunteers

Post-traumatic epilepsy+1

Pharmacokinetic Study of Oral Marimastat (PKL-021) and Heparin Sodium in Healthy Adult Subjects

A study to compare how the body absorbs perampanel in healthy adult men and women during fasting conditions

A study to compare how the body absorbs perampanel in healthy adult men and women during fasting conditions

Angelman's syndrome

A Study Testing the Safety and How Well GTX-102 Works in Adults and Children with Angelman Syndrome

Dementia Alzheimer's type

Study of Trontinemab Compared to Placebo for Patients with Early Symptomatic Alzheimer's Disease

Dementia Alzheimer's type

A study testing trontinemab compared to placebo in patients with early Alzheimer's disease including mild cognitive impairment and mild dementia

Multiple sclerosis

A Study Comparing Two Forms of Ocrelizumab Given Under the Skin in Patients with Multiple Sclerosis

Dementia Alzheimer's type

A study testing MK-1167 added to current treatment in patients with mild to moderate Alzheimer's disease dementia

Muscle spasticity

Comparing Abobotulinumtoxin A and Onabotulinumtoxin A for Adults with Upper Limb Spasticity

Migraine

Study of Erenumab Compared to Placebo for Children and Adolescents with Episodic Migraine to Reduce Monthly Migraine Days

Migraine

A Study of Erenumab Compared to Placebo for Children and Teenagers With Chronic Migraine to Test How Well It Works and How Safe It Is

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Substances studied in this area

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