Rare diseases
Investigational molecules
Locations
293 conditions with trials, the busiest first
1 664 trials across Europe, recruiting first
Safety and Efficacy Study of FOXP3‑T4 and Aldesleukin in Patients with IPEX Syndrome
FranceMaintenance versus tapered TNF‑alpha inhibitor therapy (golimumab, etanercept, adalimumab) in children and adolescents with juvenile idiopathic arthritis
NorwayStudy of CC-97540 (CD19‑Targeted NEX‑T CAR T) versus drug combination in adults with active systemic sclerosis
BelgiumSafety and efficacy of stopping versus maintenance dose of filgotinib, tofacitinib and upadacitinib in adult ulcerative colitis patients in deep remission
FranceLong‑term Safety and Tolerability of Admilparant in Adults with Idiopathic or Progressive Pulmonary Fibrosis
AustriaEffect of High‑Dose Thiamine Hydrochloride on Fatigue in Rheumatoid Arthritis Patients: Randomized, Double‑Blind, Placebo‑Controlled Trial
DenmarkEvaluation of gaxilose (LacTEST 0.45 g) as a marker of intestinal barrier integrity in patients with celiac disease
SpainSafety and Efficacy of Dasatinib in Reducing HIV-1 Reservoir, Inflammation, and Immune Senescence in People with HIV on Long‑Term Antiretroviral Therapy
SpainOral corticosteroid tapering with ravulizumab, prednisone and prednisolone in adult patients with generalized myasthenia gravis
GermanyRituximab versus clinic‑biological monitoring for ANCA reactivation in patients with GPA or MPA (with prednisolone)
FranceEvaluating Gradual Interval Extension of Tezepelumab in Drug Combination for Patients with Severe Asthma
The NetherlandsEvaluation of zirconium-89 crefmirlimab berdoxam PET imaging for monitoring renal allograft rejection in kidney transplant recipients
The NetherlandsThe therapies tested most often in Immune system disorders trials.
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