Therapeutic area

Hepatobiliary disorders – page 18

356 clinical trials
141 recruiting
239 conditions
25 countries

Clinical trials in Hepatobiliary disorders

356 trials across Europe, recruiting first

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356 clinical trials

Chronic hepatitis B

Not recruiting

Registered drugNo placebo

Study on Stopping Tenofovir Alafenamide, Tenofovir Disoproxil, and Entecavir in Patients with Chronic Hepatitis B

Registered drugNo placebo

Belgium

Participants:18–64 years · 65+ years
Substances:Entecavir
Sponsor:Antwerp University Hospital

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Cholangiocarcinoma

Not recruiting

Registered drugNo placebo

Study on Pre-Surgery Treatment for Locally Advanced Cholangiocarcinoma Using Durvalumab, Tremelimumab, Cisplatin, and Gemcitabine

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Cisplatin
Sponsor:IRCCS Istituto Nazionale Tumori Fondazione Pascale

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Hepatocellular carcinoma

Not recruiting

Registered drugNo placebo

Study on Fecal Microbiota Transplant with Atezolizumab and Bevacizumab for Liver Cancer Patients Unresponsive to Previous Immunotherapy

Registered drugNo placebo

Austria

Participants:18–64 years · 65+ years
Substances:Atezolizumab
Sponsor:Medical University Of Vienna

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Alpha-1 antitrypsin deficiency

Not recruiting

InvestigationalNo placebo

Study on the Safety and Tolerability of WVE-006 for Patients with Alpha-1 Antitrypsin Deficiency (AATD) Pi*ZZ

InvestigationalNo placebo

Finland

Participants:18–64 years · 65+ years
Substances:Wve-006
Sponsor:Wave Life Sciences Ireland Limited

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Polycystic liver disease

Not recruiting

Registered drugNo placebo

Study on Leuprorelin Acetate for Slowing Disease Progression in Premenopausal Women with Severe Polycystic Liver Disease

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Leuprorelin Acetate
Sponsor:Universitair Medisch Centrum Groningen

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Bile acid synthesis disorder

Not recruiting

Registered drugNo placebo

Long-term Safety Study of Cholic Acid for Patients with Bile Acid Synthesis Defects

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Cholic Acid
Sponsor:Amsterdam UMC

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Hepatic cirrhosis

Not recruiting

Investigational

Study of Resmetirom in Patients with Well-compensated Non-alcoholic Steatohepatitis (NASH) Cirrhosis to Evaluate Effects on Liver Health

Investigational

Belgium

Participants:18–64 years · 65+ years
Substances:Resmetirom
Sponsor:Madrigal Pharmaceuticals Inc.

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Porphyria non-acute

Not recruiting

InvestigationalNo placebo

Study on the Safety and Tolerability of Oral Dersimelagon for Patients with Erythropoietic Protoporphyria or X-Linked Protoporphyria

InvestigationalNo placebo

Bulgaria

Participants:0–17 years · 18–64 years · 65+ years
Substances:Dersimelagon Phosphate
Sponsor:Tanabe Pharma America Inc.

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Chronic hepatitis B

Not recruiting

Registered drug

Study on the Safety and Effectiveness of Terbinafine for Patients with Chronic Hepatitis B

Registered drug

The Netherlands

Participants:18–64 years
Substances:Terbinafine
Sponsor:Amsterdam UMC

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Primary biliary cholangitis

Not recruiting

Registered drugNo placebo

Study on the Effects of Bezafibrate and Obeticholic Acid for Patients with Primary Biliary Cholangitis

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Bezafibrate
Sponsor:Intercept Pharmaceuticals Inc.

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Neuroendocrine carcinoma of the skin+9

Not recruiting

Registered drugNo placebo

Study on Reduced Dose Intensity of Pembrolizumab and Drug Combination for Patients with Advanced or Metastatic Cancer Responding to Standard Immunotherapy

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Atezolizumab
Sponsor:Unicancer

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Metabolic dysfunction-associated steatohepatitis+1

Not recruiting

Investigational

Study on Efinopegdutide for Adults with Compensated Cirrhosis Due to Metabolic Dysfunction-Associated Steatohepatitis

Investigational

France

Participants:18–64 years · 65+ years
Substances:Efinopegdutide
Sponsor:Merck Sharp & Dohme LLC

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Substances studied in this area

The therapies tested most often in Hepatobiliary disorders trials.

Durvalumab37 clinical trials Bevacizumab29 clinical trials Atezolizumab27 clinical trials Cisplatin26 clinical trials Lenvatinib22 clinical trials Tremelimumab22 clinical trials Gemcitabine20 clinical trials Infliximab15 clinical trials Mycophenolate Mofetil15 clinical trials

Hepatobiliary disorders – page 18

Conditions in this area

Clinical trials in Hepatobiliary disorders

356 clinical trials

Chronic hepatitis B

Study on Stopping Tenofovir Alafenamide, Tenofovir Disoproxil, and Entecavir in Patients with Chronic Hepatitis B

Cholangiocarcinoma

Study on Pre-Surgery Treatment for Locally Advanced Cholangiocarcinoma Using Durvalumab, Tremelimumab, Cisplatin, and Gemcitabine

Hepatocellular carcinoma

Study on Fecal Microbiota Transplant with Atezolizumab and Bevacizumab for Liver Cancer Patients Unresponsive to Previous Immunotherapy

Alpha-1 antitrypsin deficiency

Study on the Safety and Tolerability of WVE-006 for Patients with Alpha-1 Antitrypsin Deficiency (AATD) Pi*ZZ

Polycystic liver disease

Study on Leuprorelin Acetate for Slowing Disease Progression in Premenopausal Women with Severe Polycystic Liver Disease

Bile acid synthesis disorder

Long-term Safety Study of Cholic Acid for Patients with Bile Acid Synthesis Defects

Hepatic cirrhosis

Study of Resmetirom in Patients with Well-compensated Non-alcoholic Steatohepatitis (NASH) Cirrhosis to Evaluate Effects on Liver Health

Porphyria non-acute

Study on the Safety and Tolerability of Oral Dersimelagon for Patients with Erythropoietic Protoporphyria or X-Linked Protoporphyria

Chronic hepatitis B

Study on the Safety and Effectiveness of Terbinafine for Patients with Chronic Hepatitis B

Primary biliary cholangitis

Study on the Effects of Bezafibrate and Obeticholic Acid for Patients with Primary Biliary Cholangitis

Neuroendocrine carcinoma of the skin+9

Study on Reduced Dose Intensity of Pembrolizumab and Drug Combination for Patients with Advanced or Metastatic Cancer Responding to Standard Immunotherapy

Metabolic dysfunction-associated steatohepatitis+1

Study on Efinopegdutide for Adults with Compensated Cirrhosis Due to Metabolic Dysfunction-Associated Steatohepatitis

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Substances studied in this area

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